16S rRNA gene sequence-based identification of bacteria in automatically incubated blood culture materials from tropical sub-Saharan Africa (Publications)
BACKGROUND: The quality of microbiological diagnostic procedures depends on pre-analytic conditions. We compared the results of 16S rRNA gene PCR and sequencing from automatically incubated blood cult
Rapid discrimination of <em>Haemophilus influenzae</em>, <em>H. parainfluenzae</em>, and<em> H. haemolyticus</em> by fluorescence<em> in situ</em>... (Publications)
BACKGROUND: Due to considerable differences in pathogenicity, Haemophilus influenzae, H. parainfluenzae and H. haemolyticus have to be reliably discriminated in routine diagnostics. Retrospective anal
Rapid identification of <em>Acinetobacter</em> spp. by fluorescence <em>in situ</em> hybridization (FISH) from colony and blood culture material (Publications)
Multi-drug-resistant strains of the Acinetobacter baumannii complex cause nosocomial infections. Rapid identification of Acinetobacter spp. is desirable in order to facilitate therapeutic or hygiene d
Identification of lymphogranuloma venereum-associated <em>Chlamydia trachomatis</em> serovars by fluorescence <em>in situ</em> hybridisation--a... (Publications)
We describe a proof-of-principle evaluation of a fluorescence in situ hybridisation (FISH) procedure to identify Chlamydia trachomatis serovars L1-L3, the causative agents of lymphogranuloma venereum,
Regional differences and trends in breast cancer surgical procedures and their relation to socioeconomic disparities and screening patterns (Publications)
BackgroundImportant regional disparities in patterns of care in breast cancer have recently been described. In Switzerland,nationwide data on hospitalisations have been collected since 1998. They have
A multiplex qPCR approach for detection of <em>pfhrp2 </em>and <em>pfhrp3</em> gene deletions in multiple strain infections of <em>Plasmodium... (Publications)
The rapid and accurate diagnosis of Plasmodium falciparum malaria infection is an essential factor in malaria control. Currently, malaria diagnosis in the field depends heavily on using rapid diagnost
Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in <em>Plasmodium falciparum</em> (Publications)
Malaria eradication is critically dependent on new therapeutics that target resistant Plasmodium parasites and block transmission of the disease. Here, we report that pantothenamide bioisosteres were
The genetic background modulates the evolution of fluoroquinolone-resistance in <em>Mycobacterium tuberculosis</em> (Publications)
Fluoroquinolones (FQ) form the backbone in experimental treatment regimens against drug-susceptible tuberculosis. However, little is known on whether the genetic variation present in natural populatio