Repellents and new "spaces of concern" in global health (Publications)
Today, malaria prevention hinges upon two domestic interventions: insecticide-treated bed nets and indoor residual spraying. As mosquitoes grow resistant to these tools, however, novel approaches to vector [...] vector control have become a priority area of malaria research and development. Spatial repellency, a volumetric mode of action that seeks to reduce disease transmission by creating an atmosphere inimical [...] of a non-insecticidal paradigm of vector control for how we understand the...
Creating an "enabling environment" for taking insecticide treated nets to national scale: the Tanzanian experience (Publications)
of its population at high risk of malaria by 2005. The country is, therefore, determined to ensure that sustainable malaria control using insecticide-treated nets is carried out on a national scale. CASE [...] INTRODUCTION: Malaria is the largest cause of health services attendance, hospital admissions and child deaths in Tanzania. At the Abuja Summit in April 2000 Tanzania committed itself to protect 60% of [...] been involved for two decades in the research process for developing...
New Vector Control Interventions (Page)
https://www.swisstph.ch/de/about/eph/vector-biology/new-vector-control-interventions
odour-based 'push-pull' malaria vector control strategy in reducing human-vector contact. Sci Rep . 2023;13:11197. DOI: 10.1038/s41598-023-38463-5 Georgiades M et al. Hearing of malaria mosquitoes is modulated [...] Access (ViALLIN MUsAcc) Long-lasting insecticidal nets (LLINs), or bed nets, are the mainstay of malaria control. However, more than 50% of people living in endemic areas are currently unprotected because [...] expected lifespan. The aim of this project is to develop a digital tool...
Differential expression of var gene groups is associated with morbidity caused by <em>Plasmodium falciparum </em>infection in Tanzanian children (Publications)
uncomplicated, and asymptomatic malaria. Transcripts of var group A and B genes were more abundant in patients with severe malaria than in patients with uncomplicated malaria. In general, the transcript [...] abundances of var group A and B genes were higher for children with clinical malaria than for children with asymptomatic infections. The var group C and var1-like transcript abundances were similar between
Melissa Penny speaks about the beauty of disease modelling (Blog)
https://www.swisstph.ch/de/impact-stories/the-beauty-of-disease-modelling/blog-id/25
disease modelling for over 15 years. She joins us today to discuss the first malaria vaccine, disease modelling and the future of malaria eradication.
The use of the polymerase chain reaction for more sensitive detection of <em>Plasmodium falciparum</em> (Publications)
positive for P. vivax and P. malariae an underlying P. falciparum infection remained undetected by microscopy. The introduction of PCR has opened up new possibilities in malaria diagnosis and research. [...] The prevalence of Plasmodium falciparum in children and adults living in a malaria-endemic area in Papua New Guinea was determined by microscopy and by polymerase chain reaction (PCR). The sensitivity
Distribution of survival times of deliberate <em>Plasmodium falciparum</em> infections in tertiary syphilis patients (Publications)
has important implications for mathematical modelling of malaria, which has for the past century exclusively assumed that the duration of malaria infections has an exponential distribution. It is desirable [...] influences the length of monitoring needed in an intervention programme for eliminating or reducing malaria
Clara Champagne (People)
https://www.swisstph.ch/de/staff/profile/people/clara-champagne
making on malaria interventions. Her recent work includes P. vivax modelling with applications in Central America and South-East Asia, the use of a model with human movement to represent malaria dynamics [...] health worker geographical placement. She has also participated in the modelling work supporting malaria control programmes within the HBHI initiative. Complete publication list available on Google Scholar
Claudia Daubenberger Appointed Professor at the University of Basel (News)
https://www.swisstph.ch/de/news/news-detail-1/news/claudia-daubenberger-appointed-professor-at-the-university-of-basel
the Faculty of Science and the Faculty of Medicine. Daubenberger’s research focuses on evaluating malaria vaccine development approaches in sub-Saharan Africa and on understanding the immunology of host-pathogen [...] populations. “Claudia Daubenberger’s research has deepened our understanding of immune responses against malaria and other infectious diseases of poverty, which provides a foundation to develop markers for protection [...] will further intensify research at the interface of...
MOSASWA Modelling Support (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/mosaswa-modelling-support
Indoor Residual Spraying (IRS) by Tchau Tchau Malaria (Goodbye Malaria, TTM) in Southern Mozambique as part of the MOSASWA (Mozambique, South Africa and Eswatini) initiative. The evaluation included three [...] The Global Fund to Fight AIDS, Tuberculosis and Malaria (The Global Fund) has commissioned Swiss TPH to evaluate the impact of the Lubombo Spatial Development Initiative 2 (LSDI2) implementation of Indoor [...] Group to create a connected model with data collated from the region that will...