Gesucht nach malaria.

1. Residual malaria infections in pre-elimination scenarios: how does detectability relate to prevalence? (Publications)

   Residual malaria infections in pre-elimination scenarios: how does detectability relate to prevalence?

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2. Identification and characterization of heme-interacting proteins in the malaria parasite, <em>Plasmodium falciparum</em> (Publications)

   Identification and characterization of heme-interacting proteins in the malaria parasite, <em>Plasmodium falciparum</em>

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3. Personal protection against malaria, excluding drugs (Publications)

   Personal protection against malaria, excluding drugs

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4. Exploratory case series of febrile adult patients in a holoendemic area of Tanzania: Assessment of potential risk indicators for clinical malaria (Publications)

   Exploratory case series of febrile adult patients in a holoendemic area of Tanzania: Assessment of potential risk indicators for clinical malaria

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5. Evaluation of the in vitro antimalarial and malaria prophylactic activity of eight Ficus species (Publications)

   Evaluation of the in vitro antimalarial and malaria prophylactic activity of eight Ficus species

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6. Cantilever sensor array-based diagnostic device to monitor the humoral immune response against malaria vaccine candidates (Publications)

   Cantilever sensor array-based diagnostic device to monitor the humoral immune response against malaria vaccine candidates

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7. Lessons from malaria control activities in urban West Africa using a research - action - capacity approach (Publications)

   Lessons from malaria control activities in urban West Africa using a research - action - capacity approach

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8. Emulator-based Bayesian optimization for efficient multi-objective calibration of an individual-based model of malaria (Publications)

   Emulator-based Bayesian optimization for efficient multi-objective calibration of an individual-based model of malaria

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   framework employing Gaussian process or machine learning emulator functions to calibrate a complex malaria transmission simulator. We demonstrate our approach by optimizing over a high-dimensional parameter [...] a portfolio of multiple fitting objectives built from datasets capturing the natural history of malaria transmission and disease progression. Our approach quickly outperforms previous calibrations, yielding

9. The 3-phosphoinositide-dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites (Publications)

   The 3-phosphoinositide-dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites

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   t protein kinase A (PKA) signalling is essential for the proliferation of Plasmodium falciparum malaria blood stage parasites. The mechanisms regulating the activity of the catalytic subunit PfPKAc, however [...] function has not been investigated in gametocytes, the sexual blood stage forms that are essential for malaria transmission. By studying a conditional PfPKAc knockdown (cKD) mutant, we confirm the essential role

10. Characterising co-infections with <em>Plasmodium </em>spp., <em>Mansonella perstans</em> or <em>Loa loa </em>in asymptomatic children, adults and... (Publications)

    Characterising co-infections with <em>Plasmodium </em>spp., <em>Mansonella perstans</em> or <em>Loa loa </em>in asymptomatic children, adults and elderly people living on Bioko Island using nucleic acids extracted from malaria rapid diagnostic tests

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    Equatorial Guinea are lacking. We aimed to demonstrate that blood retained on malaria rapid diagnostic tests, commonly deployed for malaria surveys, could be used as a source of nucleic acids for molecular based [...] with malaria in an asymptomatic population. METHODOLOGY: M. perstans, L. loa and Plasmodium spp. parasites were monitored by qPCR in a cross-sectional study using DNA extracted from a subset malaria rapid [...] rapid diagnostic tests (mRDTs) collected during the annual malaria...