Forschung zu Armutskrankheiten (Page)
https://www.swisstph.ch/de/ueber-uns/unterstuetzen-sie-uns/forschung-zu-armutskrankheiten
Grundversorgung und Erfolgen bei der Bekämpfung von Infektionskrankheiten wie Cholera, Pocken und Malaria. Infolgedessen hat sich die Gesundheit vieler, aber längst nicht aller Menschen verbessert. Im globalen [...] globalen Süden, wo die grosse Mehrheit der Weltbevölkerung lebt, ist die Sterblichkeitsrate durch Malaria, Tuberkulose und andere armutsbedingte Infektionskrankheiten bis heute erschreckend hoch. Die Erforschung
Massive Open Online Course on Insecticide Resistance Management (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/massive-open-online-course-on-insecticide-resistance-management
the authoritative resource for Insecticide Resistance Management (IRM) in the mosquito vectors of malaria. However, IRM is an applied science, and there is a need to translate theory into practice. Whilst [...] to anyone, but will be specifically designed for, and promoted to, those involved with practical malaria vector control. <!-- [if gte mso 9]> <
Antimalarial agents derived from metal-amodiaquine complexes with activity in multiple stages of the plasmodium life cycle (Publications)
Quinolines are excellent ligands for metal coordination and are deployed as drugs for malaria treatment. There is a growing body of evidence indicating that metal complexes can be conjugated with antimalarial [...] findings indicate that metal coordination is a potential chemical tool for drug design and discovery in malaria.
Massive Open Online Course on Insecticide Resistance Management (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/massive-open-online-course-on-insecticide-resistance-management
the authoritative resource for Insecticide Resistance Management (IRM) in the mosquito vectors of malaria. However, IRM is an applied science, and there is a need to translate theory into practice. Whilst [...] to anyone, but will be specifically designed for, and promoted to, those involved with practical malaria vector control. <!-- [if gte mso 9]> <
Synthesis and structure-activity relationships of new 2-phenoxybenzamides with antiplasmodial activity (Publications)
The 2-phenoxybenzamide 1 from theMedicines for Malaria Venture Malaria Box Project has shown promising multi-stage activity against different strains of P. falciparum. It was successfully synthesized via
Cytotoxic T lymphocyte (CTL) low-responsiveness to the <em>Plasmodium falciparum</em> circumsporozoite protein in naturally-exposed endemic... (Publications)
epitope(s) within the circumsporozoite (CS) protein of malaria sporozoites have been shown to play an important role in protective immunity against malaria, at least in murine models. Their role in sporozoite
Molecular surveillance of the antifolateresistant mutation I164L in imported African isolates of <em>Plasmodium falciparum</em> in Europe: sentinel... (Publications)
BACKGROUND: Malaria parasites that carry the DHFR-mutation I164L are not only highly resistant to sulfadoxine-pyrimethamine but also to the new antimalarial drug chlorproguanil-dapsone. The spread of this [...] network for the surveillance of travel-associated diseases and seems to cover approximately 12% of all malaria cases imported into Europe. Within this network we screened 277 imported African isolates of P.
In vitro antiprotozoal activities and cytotoxicity of some selected Cameroonian medicinal plants (Publications)
Eight extracts from seven selected Cameroonian medicinal plants, traditionally used to treat malaria and other protozoal diseases, were tested in vitro for their antiprotozoal activities against Plasm [...] Leishmania donovani, Trypanosoma cruzi and Trypanosoma brucei rhodesiense, protozoa responsible for malaria, visceral leishmaniasis, Chagas disease and African trypanosomiasis, respectively. The most active
Field-caught permethrin-resistant <em>Anopheles gambiae</em> overexpress CYP6P3, a P450 that metabolises pyrethroids (Publications)
Resistance to pyrethroid insecticides in the malaria vector Anopheles gambiae is receiving increasing attention because it threatens the sustainability of malaria vector control programs in sub-Saharan Africa
Epidemiology of multiple <em>Plasmodium falciparum</em> infections. 6. Multiple <em>Plasmodium falciparum</em> infections in Tanzanian infants (Publications)
clinical malaria, in contrast to the situation in older children (> 2 years). The findings help in the understanding of infection dynamics, premunition, and development of semi-immunity in malaria.