Malaria: a major health problem within an oil palm plantation around Popondetta, Papua New Guinea (Publications)
023 malaria cases were diagnosed at the aid posts and malaria accounted for 30-40% of all clinical cases. Of the malaria cases, 13-20% were HOP employees. On average, an employee sick with malaria was [...] BACKGROUND: For companies operating in malaria endemic countries, malaria represents a substantial risk to workers and their dependants, and can lead to significantly reduced worker productivity. This [...] 2006. Sleeping outside of the house did not increase the risk of a malaria infection,...
What should vaccine developers ask? Simulation of the effectiveness of malaria vaccines (Publications)
effects of malaria vaccines on malaria transmission, morbidity and mortality. The models are fitted and simulations obtained via volunteer computing. We consider a range of endemic malaria settings with [...] BACKGROUND: A number of different malaria vaccine candidates are currently in pre-clinical or clinical development. Even though they vary greatly in their characteristics, it is unlikely that any of them [...] them will provide long-lasting sterilizing immunity against the malaria parasite....
Epidemiology and clinical features of vivax malaria imported to Europe: sentinel surveillance data from TropNetEurop (Publications)
Plasmodium vivax is the second most common species among malaria patients diagnosed in Europe, but epidemiological and clinical data on imported P. vivax malaria are limited. The TropNetEurop surveillance network [...] network has monitored the importation of vivax malaria into Europe since 1999. OBJECTIVES: To present epidemiological and clinical data on imported P. vivax malaria collected at European level. MATERIAL AND [...] AND METHODS: Data of primary cases of P. vivax malaria reported...
Mapping malaria risk among children in Côte d'Ivoire using Bayesian geo-statistical models (Publications)
estimated 767,000 disability-adjusted life years are due to malaria, placing the country at position number 14 with regard to the global burden of malaria. Risk maps are important to guide control interventions [...] ons, and hence, the aim of this study was to predict the geographical distribution of malaria infection risk in children aged
A review of malaria vaccine clinical projects based on the WHO rainbow table (Publications)
As the malaria community considers the potential role of a first-generation malaria vaccine in malaria control efforts, it is an apposite time to carefully document terminated and ongoing malaria vaccine [...] Phase 3 testing of the most advanced malaria vaccine, RTS,S/AS01, indicates that malaria vaccine R&D is moving into a new phase. Field trials of several research malaria vaccines have also confirmed that [...] applied to increase the chances of success for second-generation malaria...
Cost-effectiveness of intermittent preventive treatment of malaria in infants (IPTi) for averting anaemia in Gabon: a comparison between intention to... (Publications)
BACKGROUND: In Gabon, the impact of intermittent preventive treatment of malaria in infants (IPTi) was not statistically significant on malaria reduction, but the impact on moderate anaemia was, with some differences
Varying efficacy of intermittent preventive treatment for malaria in infants in two similar trials: public health implications (Publications)
in the risk of clinical malaria between the second and the third dose; during the same period, there was no significant effect in Manhica. Similarly, protection against malaria episodes was maintained [...] explanation for the difference in IPTi efficacy on clinical malaria. Combination of IPTi and ITNs may be the most cost-effective tool for malaria control currently available, and needs to be explored in current [...] (IPTi) with sulphadoxine-pyrimethamine (SP) in infants resulted in different...
The effects of untreated bednets on malaria infection and morbidity on the Kenyan coast (Publications)
protected against both malaria infection and clinical disease compared with children not sleeping under bednets. The study was conducted in Kilifi District, Kenya, during the malaria season (June-August, [...] P = 0.47). When these same children were followed-up during the malaria season, there was evidence of a lower rate of clinical malaria among those that used untreated nets in good condition (adjusted [...] or = 10 years. Data collected from a cross-sectional survey showed evidence of...
