Discovery and optimisation studies of antimalarial phenotypic hits (Publications)
There is an urgent need for the development of new antimalarial compounds. As a result of a phenotypic screen, several compounds with potent activity against the parasite Plasmodium falciparum were id
Outcomes mapping study for childhood vaccination communication: too few concepts were measured in too many ways (Publications)
OBJECTIVES: The objectives of this paper are: 1) to comprehensively catalogue outcomes measured in trials of childhood vaccination communication interventions; and 2) to analyse patterns and trends in
Progress with <em>Plasmodium falciparum </em>sporozoite (PfSPZ)-based malaria vaccines (Publications)
Sanaria Inc. has developed methods to manufacture, purify and cryopreserve aseptic Plasmodium falciparum (Pf) sporozoites (SPZ), and is using this platform technology to develop an injectable PfSPZ-ba
Ability of physicians to diagnose influenza and usefulness of a rapid influenza antigen test in febrile returning travelers: a randomized controlled... (Publications)
BACKGROUND: Fever is a frequent cause of medical consultation among returning travelers. The objectives of this study were to assess whether physicians were able to identify patients with influenza an
The effect of malaria control on <em>Plasmodium falciparum</em> in Africa between 2000 and 2015 (Publications)
Since the year 2000, a concerted campaign against malaria has led to unprecedented levels of intervention coverage across sub-Saharan Africa. Understanding the effect of this control effort is vital t
Blood or urine IP-10 cannot discriminate between active tuberculosis and respiratory diseases different from tuberculosis in children (Publications)
OBJECTIVES: Interferon-? inducible protein 10 (IP-10), either in blood or in urine, has been proposed as a tuberculosis (TB) biomarker for adults. This study aims to evaluate the potential of IP-10 di
RFX transcription factors are essential for hearing in mice (Publications)
Sensorineural hearing loss is a common and currently irreversible disorder, because mammalian hair cells (HCs) do not regenerate and current stem cell and gene delivery protocols result only in immatu