Estimating the extent, patterns and consequences of heterogeneity in malaria dynamics (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/estimating-the-extent-patterns-and-consequences-of-heterogeneity-in-malaria-dynamics
Background The uneven distribution of malaria is apparent on a small scale, within a single study site or even cluster of houses. Transmission varies with mosquito densities related to breeding sites, [...] relatively high transmission, have been identified. Heterogeneity has implications for many areas of malaria epidemiology, not least the design of intervention strategies. Whilst the existence of heterogeneity [...] heterogeneity, and inform the design of control strategies and the...
NETCELL Phase 5 - Core support to the National Malaria Control Programme in Tanzania (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/netcell-phase-5-core-support-to-the-national-malaria-control-programme-in-tanzania
Since its inception in 2002 the NETCELL Project has played a key role in supporting the National Malaria Control Programme (NMCP) of the Tanzanian Ministry of Health and Social Welfare, by managing the [...] Insecticide Treated Net (NATNETS) Programme. Over 200 million dollars of international donor funding for malaria prevention have been leveraged for the MoHSW in the past decade, and the NATNETS programme has been [...] focus on technical advice and strategic support; 2) an extension of...
Global Malaria Technical & Training Support Package, Phase 4 (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/global-malaria-technical-training-support-package-phase-4
control, case management (malaria treatment) and cross-sectoral action against malaria, and through the training of malaria affected countries’ scientists and national malaria control managers. GlobMal [...] strategic direction towards the ambitious 2030 malaria goals to reduce malaria mortality by 40% by 2020 (compared with 2015) and to increase the number of malaria-free countries by additional 10 and 35 countries [...] contribute to global malaria control and elimination by shaping global and...
PATH - MVI Malaria Vaccine Modeling: Service Agreement (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/path-mvi-malaria-vaccine-modeling-service-agreement
Swiss TPH is carrying out simulations of the public health impact of the RTS,S malaria vaccine, with the support of PATH-MVI. The work involves simulation of the impact of adding vaccines in the context [...] countries in sub-Saharan Africa, taking into account contextual factors such as the distributions of malaria transmission intensities. Vaccine profiles are based on field data from Phase III trials of RTS,S
Assessing the variability in experimental hut trials evaluating insecticide-treated nets against malaria vectors (Publications)
Experimental hut trials (EHTs) are used to evaluate indoor vector control interventions against malaria vectors in a controlled setting. The level of variability present in the assay will influence whether
Species composition and insecticide resistance in malaria vectors in Ellibou, southern Côte d’Ivoire and first finding of <em>Anopheles... (Publications)
status of the target vector population is important to guide malaria vector control. The aim of this study was to characterize the malaria vector population in terms of species composition, insecticide [...] an early warning sign, as An. arabiensis shows a different biology than the currently documented malaria vectors. Because the local An. gambiae population was still susceptible to malathion, upregulation
The troubled puberty of malaria parasites (Publications)
Sexual differentiation of malaria parasites is essential for transmission, yet the underlying mechanisms are poorly understood. Russell et al. elegantly combined a loss-of-function screen with single-cell