A var gene upstream element controls protein synthesis at the level of translation initiation in <em>Plasmodium falciparum</em> (Publications)
Clonally variant protein expression in the malaria parasite Plasmodium falciparum generates phenotypic variability and allows isogenic populations to adapt to environmental changes encountered during
Late onset of the serological response against the 18 kDa small heat shock protein of <em>Mycobacterium ulcerans</em> in children (Publications)
A previous survey for clinical cases of Buruli ulcer (BU) in the Mape Basin of Cameroon suggested that, compared to older age groups, very young children may be less exposed to Mycobacterium ulcerans.
The challenge to avoid anti-malarial medicine stock-outs in an area of funding partners: the case of Tanzania (Publications)
BACKGROUND: Between 2007 and 2013, the Tanzanian public sector received 93.1 million doses of first-line anti-malarial artemisinin-based combination therapy (ACT) in the form of artemether-lumefantrin
Effective autodissemination of pyriproxyfen to breeding sites by the exophilic malaria vector <em>Anopheles arabiensis</em> in semi-field settings in... (Publications)
BACKGROUND: Malaria vector control strategies that target adult female mosquitoes are challenged by the emergence of insecticide resistance and behavioural resilience. Conventional larviciding is rest
The epidemiology of malaria and anaemia in the Bonikro mining area, central Côte d'Ivoire (Publications)
BACKGROUND: The epidemiology of malaria and anaemia is characterized by small-scale spatial and temporal heterogeneity, which might be influenced by human activities, such as mining and related distur
Modelling heterogeneity in malaria transmission using large sparse spatio-temporal entomological data (Publications)
Background: Malaria transmission is measured using entomological inoculation rate (EIR), number of infective mosquito bites/person/unit time. Understanding heterogeneity of malaria transmission has be
Field comparison of circulating antibody assays <em>versus</em> circulating antigen assays for the detection of <em>Schistosomiasis japonica</em> in... (Publications)
BACKGROUND: Schistosomiasis remains a serious public health problem in affected countries, and routine, highly sensitive and cost-effective diagnostic methods are lacking. We evaluated two immunodiagn
Experimental infection of the pig with <em>Mycobacterium ulcerans</em>: a novel model for studying the pathogenesis of Buruli ulcer disease (Publications)
BACKGROUND: Buruli ulcer (BU) is a slowly progressing, necrotising disease of the skin caused by infection with Mycobacterium ulcerans. Non-ulcerative manifestations are nodules, plaques and oedema, w
<em>Plasmodium falciparum </em>infection and clinical indicators in relation to net coverage in central Côte d'Ivoire (Publications)
BACKGROUND: Sleeping under a net, particularly a long-lasting insecticidal net (LLIN), is associated with reduced malaria morbidity and mortality, but requires high coverage and adherence. In this stu