Skin and soft tissue infections in intercontinental travellers and the import of multi-resistant <em>Staphylococcus aureus</em> to Europe (Publications)
Staphylococcus aureus is emerging globally. Treatment of infections is complicated by increasing antibiotic resistance. We collected clinical data and swabs of returnees with skin and soft tissue infe
Inhibitors of plasmodial serine hydroxymethyltransferase (SHMT): cocrystal structures of pyrazolopyrans with potent blood- and liver-stage activities (Publications)
Several of the enzymes related to the folate cycle are well-known for their role as clinically validated antimalarial targets. Nevertheless for serine hydroxymethyltransferase (SHMT), one of the key e
Co-evolution of <em>Mycobacterium tuberculosis</em> and <em>Homo sapiens</em> (Publications)
The causative agent of human tuberculosis (TB), Mycobacterium tuberculosis, is an obligate pathogen that evolved to exclusively persist in human populations. For M. tuberculosis to transmit from perso
Clinical features for diagnosis of pneumonia in children younger than 5 years: a systematic review and meta-analysis (Publications)
BACKGROUND: Pneumonia is the biggest cause of deaths in young children in developing countries, but early diagnosis and intervention can effectively reduce mortality. We aimed to assess the diagnostic
Detection of <em>Mycobacterium tuberculosis</em> by EasyNAT diagnostic kit in sputum samples from Tanzania (Publications)
EasyNAT was evaluated for detection of tuberculosis in sputum smears of presumptive pulmonary TB patients in an African high TB and HIV setting. The sensitivity of EasyNAT was 66.7%, specificity and p
Molecular epidemiology suggests Venezuela as the origin of the dengue outbreak in Madeira, Portugal in 2012-2013 (Publications)
An explosive epidemic occurred in Madeira Island (Portugal) from October 2012 to February 2013. Published data showed that Dengue virus type 1 DENV-1) introduced from South America was the incriminate
The WHO ultrasonography protocol for assessing morbidity due to <em>Schistosoma haematobium</em>: acceptance and evolution over 14 years: systematic... (Publications)
In 2000, the World Health Organization (WHO) published an ultrasound field protocol for assessing morbidity due to schistosomiasis. The present study aims to review the acceptance of the WHO protocol
Impact de l'urbanisation sur l'indice plasmodique et les densités parasitaires chez les enfants de 0 à 5 ans dans la commune de Yopougon, Abidjan... (Publications)
From September 23-30, 2005, we conducted a cross-sectional study in six townships of Yopougon, a municipality of Abidjan. These townships were grouped in three levels of urbanization (village, precari
Aryl hydantoin Ro 13-3978, a broad-spectrum antischistosomal (Publications)
OBJECTIVES: Praziquantel is the only drug available for the treatment of schistosomiasis and the state of the exhausted drug discovery pipeline is alarming. We restarted investigations on the abandone
