Use of poly(amidoamine) drug conjugates for the delivery of antimalarials to <em>Plasmodium</em> (Publications)
Current malaria therapeutics demands strategies able to selectively deliver drugs to Plasmodium-infected red blood cells (pRBCs) in order to limit the appearance of parasite resistance. Here, the poly
Dioncophyllines C2, D2, and F and related naphthylisoquinoline alkaloids from the Congolese liana <em>Ancistrocladus ileboensis</em> with potent... (Publications)
CEM/ADR5000. Moreover, the dioncophyllines 1, 3, and 7 showed high-and specific-activities against the malaria parasite Plasmodium falciparum.
<em>In vitro</em> and<em> in vivo</em> activity of Solithromycin (CEM-101) against <em>Plasmodium</em> species (Publications)
the same dose required for artesunate or chloroquine to achieve 100% cure rates in this rodent malaria model. These promising in vitro and in vivo data support further investigations into the development
Genomic distribution and functional characterisation of two distinct and conserved <em>Plasmodium falciparum</em> var gene 5' flanking sequences (Publications)
Approximately 50 highly diverse var genes distributed throughout the haploid genome of the malaria parasite Plasmodium falciparum code for PfEMP1 variants located on the surface of infected erythrocytes
Multiple parasite infections and their relationship to self-reported morbidity in a community of rural Côte d'Ivoire (Publications)
soil-transmitted helminths and intestinal protozoa. Giemsa-stained blood smears were analysed for malaria parasites. A questionnaire was administered for collection of demographic information and self-reported
The reliability of pre-travel history to decide on appropriate counseling and vaccinations: a prospective study (Publications)
history and the effect on advice regarding the administration of vaccines and recommendations for malaria prevention.METHODS: We included prospectively all consenting adults who had not planned an organized
Bromopyrrole alkaloids as lead compounds against protozoan parasites (Publications)
chloroquine resistant strain), responsible of human diseases with high morbidity and, in the case of malaria, high mortality. Our results indicate longamide B (8) and dibromopalau'amine (11) to be promising
Retrospective study on the usefulness of pulse oximetry for the identification of young children with severe illnesses and severe pneumonia in a rural... (Publications)
episodes in an intervention trial assessing the efficacy of Intermittent Preventive Treatment for malaria in infants (IPTi) in Papua New Guinea (PNG) from June 2006 to May 2010. SETTING: The IPTi study was
Prognostic value of quickSOFA as a predictor of 28-day mortality among febrile adult patients presenting to emergency departments in Dar es Salaam,... (Publications)
origin. The most common site and causes of infections were the respiratory tract (43%), dengue (26%), malaria (6%) and typhoid fever (5%). Twenty-eight-day all-cause mortality was 6%: 3% for patients with a
Effect of insecticide-treated bed nets on the dynamics of multiple <em>Plasmodium falciparum</em> infections (Publications)
areas of high P. falciparum endemicity, ITNs have little effect on the establishment of chronic malaria infection.