MalCommit - Understanding Sexual Commitment and Early Differentiation of Malaria Transmission Stages (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/malcommit-understanding-sexual-commitment-and-early-differentiation-of-malaria-transmission-stages
The project aims to understand the processes responsible for the differentiation of asexual malaria blood stage parasites into sexual forms. The anticipated results may open up new avenues for the development
Evaluation of the Papua New Guinea National Malaria Control Program, 2015-2017 (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/evaluation-of-the-papua-new-guinea-national-malaria-control-program-2015-2017
AIDS, Tuberculosis and Malaria for the implementation of its malaria control program for the period 2015-2017. A range of partners are involved in the implementation of malaria control interventions ( [...] Against Malaria (RAM) and Population Services International (PSI) . The Papua New Guinea Institute of Medical Research (PNGIMR) has provided outcome and impact evaluation for the National Malaria Control
Key factors predicting suspected severe malaria case management and health outcomes: an operational study in the Democratic Republic of the Congo (Publications)
Artesunate (RAS) can be a life-saving intervention for severe malaria in remote settings in Africa. Recognition of danger signs indicative of severe malaria is critical for prompt and appropriate case management [...] of the Democratic Republic of the Congo to determine the distribution of dangers signs for severe malaria and assess their impact on RAS use, referral completion, injectable treatment and ACT provision, [...] that mortality was higher in children not receiving RAS (aOR = 1.50, 95%...
Participatory approaches for raising awareness among subsistence farmers in Tanzania about the spread of insecticide resistance in malaria vectors and... (Publications)
pesticide awareness, practices, and opinions of; insecticide resistance in malaria vectors; the effectiveness of current malaria prevention tools; and the links between agricultural and public health pesticide [...] three quarters had never heard of resistance in malaria mosquitoes. Experts from various sectors acknowledged that agricultural pesticides might impact malaria control through increasing resistance. They did [...] BACKGROUND: Insecticide resistance is a key barrier to long-term malar...
Effectiveness of rectal artesunate as pre-referral treatment for severe malaria in children under 5 years of age: a multi-country observational study (Publications)
BACKGROUND: To prevent child deaths from severe malaria, early parenteral treatment is essential. Yet, in remote rural areas, accessing facilities offering parenteral antimalarials may be difficult. A
Community access to rectal artesunate for malaria (CARAMAL): a large-scale observational implementation study in the Democratic Republic of the Congo,... (Publications)
The key to reducing malaria deaths in highly endemic areas is prompt access to quality case management. Given that many severe cases occur at peripheral level, rectal artesunate (RAS) in the form of s [...] determinants for optimal impact. From 2018 to 2020, the Community Access to Rectal Artesunate for Malaria (CARAMAL) project was conducted as a large-scale observational implementation study in the Democratic [...] provide high-quality field evidence on the two issues above, in three remote...
Exploring a tetrahydroquinoline antimalarial hit from the medicines for malaria pathogen box and the identification of its mode of resistance as... (Publications)
of 400 compounds that was made available by Medicines for Malaria Venture (MMV) in 2015. Compound 2 was profiled in in vitro models of malaria and was found to be active against multiple life-cycle stages
Volatile pyrethroid spatial repellents for malaria prevention (Publications)
spatial repellents (VPSRs) for preventing new cases of Plasmodium falciparum and Plasmodium vivax malaria. Copyright © 2022 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
Performance of antigen detection for HRP2-based malaria rapid diagnostic tests in community surveys: Tanzania, July-November 2017 (Publications)
BACKGROUND: Malaria rapid diagnostic tests (RDTs) based on the detection of the Plasmodium falciparum histidine-rich protein 2 (HRP2) antigen are widely used for detection of active infection with this [...] this parasite and are the only practical malaria diagnostic test in some endemic settings. External validation of RDT results from field surveys can confirm appropriate RDT performance. METHODS: A community-based [...] sites can help interpret RDT testing results when generating population...