Respiratory and allergic outcomes among farmworkers exposed to pesticides in Costa Rica (Publications)
AIM: We examined the association of exposure to a pesticide mixture with respiratory and allergic outcomes among farmworkers from Costa Rica. METHODS: We conducted a cross-sectional study of 299 farmw
HIV co-infection increases the risk of post-tuberculosis mortality among persons who initiated treatment for drug-resistant tuberculosis (Publications)
Little is known regarding the relationship between common comorbidities in persons with tuberculosis (TB) (including human immunodeficiency virus [HIV], diabetes, and hepatitis C virus [HCV]) and post
Persistent depression in pregnant refugee and migrant women living along the Thai-Myanmar border: a secondary qualitative analysis (Publications)
BACKGROUND: Antepartum depression affects around 15% of pregnant women worldwide, and may negatively impact their infants' physical, cognitive and social development, and confer a greater risk of emot
AnophelesModel: an R package to interface mosquito bionomics, human exposure and intervention effects with models of malaria intervention impact (Publications)
In recent decades, field and semi-field studies of malaria transmission have gathered geographic-specific information about mosquito ecology, behaviour and their sensitivity to interventions. Mathemat
Awareness, treatment, and control among adults living with arterial hypertension or diabetes mellitus in two rural districts in Lesotho (Publications)
In Lesotho, the hypertension and diabetes care cascades are unknown. We measured awareness, treatment, and control of hypertension and diabetes among adults ≥18 years and identified factors associated
Resource use and costs of investigator-sponsored randomised clinical trials in Switzerland, Germany and the United Kingdom: a meta-research study (Publications)
BACKGROUND: Conducting high-quality randomised clinical trials (RCTs) is challenging and resource intensive. Funders and academic investigators depend on limited financial resources and, therefore, ne
Modeling transmission mechanism to infer treatment efficacy of different drugs and combination therapy against <em>Trichuris trichiura</em> (Publications)
Trichuris trichiura is one of four soil-transmitted helminth species that, collectively, are responsible for a considerable public health burden. The World Health Organization recommends preventive ch
Addressing the intracellular vestibule of the plasmodial lactate transporter PfFNT by p-substituted inhibitors amplifies <em>in vitro</em> activity (Publications)
Inhibition of the lactate transporter PfFNT is a valid novel mode of action against malaria parasites. Current pyridine-substituted pentafluoro-3-hydroxy-pent-2-en-1-ones act as substrate analogs with
PfSPZ Vaccine induces focused humoral immune response in HIV positive and negative Tanzanian adults (Publications)
BACKGROUND: PfSPZ Vaccine, a promising pre-erythrocytic stage malaria vaccine candidate based on whole, radiation-attenuated Plasmodium falciparum (Pf) sporozoites (SPZ), has proven safe and effective
