A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants (Publications)
Background The candidate malaria vaccine RTS,S/AS01 reduced episodes of both clinical and severe malaria in children 5 to 17 months of age by approximately 50% in an ongoing phase 3 trial. We studied infants [...] only episode of clinical malaria during the 12 months after vaccination, a coprimary end point, was analyzed with the use of Cox regression. Vaccine efficacy against all malaria episodes, vaccine efficacy [...] efficacy against severe malaria, safety, and immunogenicity were also...
Use and misuse of a discount voucher scheme as a subsidy for insecticide-treated nets for malaria control in southern Tanzania (Publications)
Since 1997, discount vouchers for insecticide-treated nets (ITNs) have been used in two rural districts of southern Tanzania as a way to target subsidies to children under 5 years and pregnant women.
Spatial analysis of malaria transmission parameters in the rice cultivation area of office du Niger, Mali (Publications)
The effects of rice growth environment on malaria transmission, taking into account spatial correlation, were assessed in the Office du Niger, Mali. Between April 1999 to January 2001, 8 quarterly entomologic [...] and showed low spatial correlations (up to 3.4 km), which suggested that small area variation in malaria transmission results mainly from variations in vector-human contact. Control strategies in rice
Effectiveness of artemether/lumefantrine for the treatment of uncomplicated <em>Plasmodium vivax</em> and <em>P. falciparum</em> malaria in young... (Publications)
uncomplicated Plasmodium falciparum (Pf) malaria, while chloroquine is still widely used for non-Pf infections. A common treatment for both vivax and falciparum malaria would be welcome.Methods. A longitudinal [...] had an infection confirmed by blood slide (BS) examination. Of these, 594 Pv and 332 Pf clinical malaria cases were included in the primary effectiveness analysis. Clinical treatment failure rates at 7 [...] 7, 28 and 42 days were 0.2%, 2.2% and 12.0% for Pv and 0.3%, 1.2% and 3.6%...
The economic cost to households of childhood malaria in Papua New Guinea: a focus on intra-country variation (Publications)
BACKGROUND We compare direct and indirect household costs associated with malaria treatment for children