Intermittent treatment for malaria and anaemia control at time of routine vaccinations in Tanzania infants: a randomised, placebo-controlled trial (Publications)
BACKGROUND: Clinical malaria and severe anaemia are major causes of paediatric hospital admission and death in many malaria-endemic settings. In the absence of an effective and affordable vaccine, control [...] were not affected by the intervention. INTERPRETATION: This new approach to malaria control reduced the rate of clinical malaria and severe anaemia by delivering an available and affordable drug through [...] assess the efficacy and safety of intermittent sulphadoxine-pyrimethamine...
An immigration-death model to estimate the duration of malaria infection when detectability of the parasite is imperfect (Publications)
that allows for the accrual of infections with age. The models are fitted to a panel data set of malaria genotype of parasites belonging to the msp2 FC27 and 3D7 allelic families from a study of the dynamics
Age and seasonal variation in the transition rates and detectability of <em>Plasmodium falciparum</em> malaria (Publications)
of Plasmodium falciparum infections is unclear, although this is an important term in models of malaria transmission. It is problematical to determine the duration of infections because of the difficulty
Towards a comprehensive simulation model of malaria epidemiology and control (Publications)
SUMMARYPlanning of the control of Plasmodium falciparum malaria leads to a need for models of malaria epidemiology that provide realistic quantitative prediction of likely epidemiological outcomes of a [...] dynamics, limit the applicability of conventional deterministic malaria models. We use individual-based stochastic simulations of malaria epidemiology to predict the impacts of interventions on infection
Prospective risk of morbidity in relation to malaria infection in an area of high endemicity of multiple species of <em>Plasmodium</em> (Publications)
Plasmodium malariae (13.8%), cross-sectional analysis found P. falciparum infection to be independent of the other species despite heterogeneities in transmission. Plasmodium vivax and P. malariae infections [...] health-center morbidity supported the idea that P. malariae infection protects against disease, but indicated greater protection against non-malaria than P. falciparum- associated fevers. Plasmodium vivax [...] infections were negatively correlated. Plasmodium malariae infection was...
