QSAR guided synthesis of simplified antiplasmodial analogs of naphthylisoquinoline alkaloids (Publications)
Naphthylisoquinoline alkaloids have attracted considerable interest because of their intriguing structure, their unique biosynthetic origin, and their biological activities against several pathogens c
Efficacy of new, concise schedule for melarsoprol in treatment of sleeping sickness caused by <em>Trypanosoma brucei gambiense</em>: a randomised... (Publications)
BACKGROUND: African trypanosomiasis is a fatal disease caused by protozoan parasites of the species Trypanosoma brucei. The disease has reached epidemic dimensions in various countries of central Afri
Improvements in physical and mental domains of quality of life by anti-ischaemic drug and revascularisation treatment in elderly men and women with... (Publications)
BACKGROUND: The severity of angina is related to a reduction in global quality of life (QoL), which may be improved by anti-ischaemic treatment. It is not known, however, whether improvements relate o
Effect of amoxicillin-clavulanate in clinically diagnosed acute rhinosinusitis: a placebo-controlled, double-blind, randomized trial in general... (Publications)
BACKGROUND: Acute rhinosinusitis is one of the most common reasons for prescribing antibiotics in primary care. However, it is not clear whether antibiotics improve the outcome for patients with clini
Auswirkungen von Luftschadstoffen auf die Atemwege von Kleinkindern (Publications)
A one year study on a random sample of 1225 Swiss children aged 0-5 years was conducted in four different areas (two urban, one suburban and one rural) of Switzerland to investigate the relationship b
Stonefish envenomation: a lucky outcome (Publications)
Stonefish are one of the most intriguing examples of a perilous marine inhabitant. Equipped with a sophisticated defence mechanism, 13 dorsal spines armed with one of the most toxic fish venoms, again