Cupiennin 1a exhibits a remarkably broad, non-stereospecific cytolytic activity on bacteria, protozoan parasites, insects, and human cancer cells (Publications)
Cupiennin 1a, a cytolytic peptide isolated from the venom of the spider Cupiennius salei, exhibits broad membranolytic activity towards bacteria, trypanosomes, and plasmodia, as well as human blood an
Soil-transmitted helminth infections and risk factors in preschool children in southern rural Lao People's Democratic Republic (Publications)
The current widespread school-based control of soil-transmitted helminth (STH) infections is also advocated for preschool children. The objective of this study was to assess infection with STHs as wel
Development and validation of a liquid chromatography/mass spectrometry method for pharmacokinetic studies of OZ78, a fasciocidal drug candidate (Publications)
Fascioliasis is a zoonotic disease of considerable public health and great veterinary significance and new drugs are needed. OZ78 is a promising fasciocidal drug candidate. In order to support the dev
Luftverschmutzung: Konsequenzen für den Hausarzt (Publications)
Air pollution can also be considered a health risk for those living in Switzerland. During short episodes of high pollution (smog), protection from exposure can be recommended. The continuous air poll
Investigating air pollution and atherosclerosis in humans: concepts and outlook (Publications)
Although ambient particulate matter contributes to atherosclerosis in animal models, its role in atherogenesis in humans needs to be established. This article discusses concepts, study design, and cho
Clinically "small" effects of air pollution on FVC have a large public health impact. Swiss Study on Air Pollution and Lung Disease in Adults... (Publications)
Epidemiological studies have repeatedly established adverse health effects due to long-term exposure to ambient air pollution. The Swiss Study on Air Pollution and Lung Disease in Adults (SAPALDIA) pu
Breathless in Los Angeles: the exhausting search for clean air (Publications)
Population growth and the proliferation of roadways in Southern California have facilitated a glut of mobile air pollution sources (cars and trucks), resulting in substantial atmospheric pollution. De
Air pollution: from lung to heart (Publications)
Epidemiological, clinical, and experimental evidence correlates current levels of ambient air pollution with both respiratory and cardiovascular effects. Oxidative stress, inflammation, induction of a
Reflections on clinical research in sub-Saharan Africa (Publications)
The urgent need for new, safe and sustainable interventions against diseases that disproportionally affect the poor is finally receiving global attention and the funding landscape for development proj
