Malaria Modelling Resource Centre (Page)
https://www.swisstph.ch/de/about/eph/disease-modelling/disease-modelling-and-intervention-dynamics/malaria-modelling-resource-centre
and to respond to specific requests for advice. The Resource Centre is built around the use of the OpenMalaria modelling platform. An introduction to the use of malaria models is presented as part of the
Total synthesis and biological investigation of (-)-artemisinin: the antimalarial activity of artemisinin is not stereospecific (Publications)
readily available S-(+)- and R-(-)-citronellene respectively. Subsequently, we have answered a still open question, i.e. specificity of artemisinins action. Using a drug sensitive Plasmodium falc. NF54 strain
Efficacy and tolerability of quinacrine monotherapy and albendazole plus chloroquine combination therapy in nitroimidazole-refractory giardiasis: a... (Publications)
data on the efficacy and tolerability of 2 second-line treatment regimens. METHODS: This prospective, open-label, multicenter study assessed the efficacy and tolerability of quinacrine monotherapy (100 mg
MMC elimination costing (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/mmc-elimination-costing
for a number of policy relevant scenarios simulated with a simulation model of malaria dyanamics (OpenMalaria), (3) synthesis of costing and modeling estimatesfor resource allocation decisions by stakeholders
Efficacy and tolerability of quinacrine monotherapy and albendazole plus chloroquine combination therapy in nitroimidazole-refractory giardiasis: a... (Publications)
data on the efficacy and tolerability of 2 second-line treatment regimens. METHODS: This prospective, open-label, multicenter study assessed the efficacy and tolerability of quinacrine monotherapy (100 mg
Total synthesis and biological investigation of (-)-artemisinin: the antimalarial activity of artemisinin is not stereospecific (Publications)
readily available S-(+)- and R-(-)-citronellene respectively. Subsequently, we have answered a still open question, i.e. specificity of artemisinins action. Using a drug sensitive Plasmodium falc. NF54 strain
Disease Modelling | Research at Swiss TPH (Page)
https://www.swisstph.ch/de/about/eph/disease-modelling
development and use of an individual-based model of malaria transmission dynamics known as OpenMalaria. This model is an open-source tool for simulating the dynamics of malaria transmission and epidemiology, and [...] Swiss TPH, our OpenMalaria model is used by a wide range of modellers worldwide. A new collaboration with the Bill & Melinda Gates Foundation supports the improvement and maintenance of OpenMalaria as well
Country modelling to support National Malaria Control Programs - High Burden to High Impact (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/country-modelling-to-support-national-malaria-control-programs-high-burden-to-high-impact
of malaria-related interventions. Our work is based on the OpenMalaria modelling platform developed by the Swiss TPH and collaborators. OpenMalaria has been developed as a decision-making support tool
Characteristics of persistent hotspots of <em>Schistosoma mansoni</em> in western Côte d'Ivoire (Publications)
infected children, was 123.8 EPG in PHS and 18.7 EPG in the other two schools. Children bathing in open freshwater bodies were at higher odds of S. mansoni infection (odds ratio: 4.5, 95% confidence interval: [...] forskalii, Bu. globosus and Bu. truncatus). CONCLUSION: Children in PHS schools bathed more frequently in open freshwater bodies, and hence, they are more exposed to Schistosoma transmission. Our findings call
Building-related health impacts in European and Chinese cities: a scalable assessment method (Publications)
impacts, both positive and negative, on public health. Our main objective was to develop a generic open impact model to estimate health impacts of emissions due to heat and power consumption of buildings [...] and large impacts on emissions. However, the life cycle impacts of different fuels is somewhat an open question. CONCLUSIONS: In conclusion, we were able to develop a practical model for city-level assessments
