Generation of chimeric monoclonal antibodies from mice that carry human immunoglobulin Cgamma1 heavy of Ckappa light chain gene segments (Publications)
Gene targeting in mouse embryonic stem (ES) cells was used to replace (i) the mouse immunoglobulin heavy chain (IgH) Cgamma2a gene segment (mCgamma2a) with the human Cgamma1 gene segment (hCgamma1), a
<em>Plasmodium falciparum</em> protein kinase 5 and the malarial nuclear division cycles (Publications)
In the course of our studies on cell cycle regulation mechanisms of Plasmodium falciparum, we investigated expression pattern, kinase activity, and localization of PfPK5, a putative malarial member of
Psychiatric disorders, suicidality, and personality among young men by sexual orientation (Publications)
Personality and its potential role in mediating risk of psychiatric disorders and suicidality are assessed by sexual orientation, using data collected among young Swiss men (n=5875) recruited while pr
Heterochromatin protein 1 secures survival and transmission of malaria parasites (Publications)
Clonally variant expression of surface antigens allows the malaria parasite Plasmodium falciparum to evade immune recognition during blood stage infection and secure malaria transmission. We demonstra
Application of the enzyme-linked immunosorbent assay (ELISA) for the diagnosis of filariasis and echinococcosis (Publications)
The Enzyme-Linked Immunosorbent Assay (ELISA) was compared with the Indirect Fluorescent Antibody Test (IFAT), the Indirect Haemagglutination Test (IHA) and Counter Immuno Electrophoresis (CIE) in the
Hydroxyurea: effect on growth, structure, and [3H]thymidine uptake of <em>Trypanosoma brucei</em> procyclic culture forms (Publications)
Hydroxyurea (HU) in concentrations above 50 micrograms/ml reversibly inhibited cell division of Trypanosoma brucei brucei stock STIB 336 procyclic culture forms, but not growth of individual cells. Th
Asymptomatic malaria infections: detectability, transmissibility and public health relevance (Publications)
Most Plasmodium falciparum infections that are detected in community surveys are characterized by low-density parasitaemia and the absence of clinical symptoms. Molecular diagnostics have shown that t