Development and validation of an enantioselective LM-MS/MS method for the analysis of the anthelmintic drug praziquantel and its main metabolite in... (Publications)
Praziquantel (PZQ) is the treatment of choice against various trematode and cestode infections. To study the pharmacokinetics of PZQ in patients infected with the liver fluke Opisthorchis viverrini, w
Cross-reactivity pattern of Asian and American human gnathostomiasis in western blot assays using crude antigens prepared from <em>Gnathostoma... (Publications)
Gnathostomiasis is a zoonotic parasitosis endemic in many Asian and some Latin American countries. Most human infections are caused by Gnathostoma spinigerum in Asia and Gnathostoma binucleatum in the
Benefits of smoking bans on preterm and early-term births: a natural experimental design in Switzerland (Publications)
BACKGROUND: Birth outcomes are relevant for future children's heath. Capitalising on a natural experimental design in Switzerland, we evaluated how regional smoking bans introduced at different time p
The intermediate host immune response in cystic echinococcosis (Publications)
Cystic echinococcosis (CE) is a chronic, complex and neglected zoonotic infection. In most cases, CE cysts and the intermediate host co-habit for a long time in the absence of symptoms and elicit very
Specificity, cross-reactivity and function of antibodies elicited by Zika virus infection (Publications)
Zika virus (ZIKV), a mosquito-borne flavivirus with homology to Dengue virus (DENV), has become a public health emergency. By characterizing memory cells from ZIKV-infected patients, we dissected ZIKV
Stakeholders' opinions and questions regarding the anticipated malaria vaccine in Tanzania (Publications)
BACKGROUND: Within the context of combined interventions, malaria vaccine may provide additional value in malaria prevention. Stakeholders' perspectives are thus critical for informed recommendation o
Efficacy and safety of oxantel pamoate in school-aged children infected with <em>Trichuris trichiura</em> on Pemba island, Tanzania: a parallel,... (Publications)
BACKGROUND: Commonly used drugs for preventive chemotherapy against soil-transmitted helminths (ie, albendazole and mebendazole) show low efficacy against Trichuris trichiura. Recent studies with oxan
Catalyzing the scale-up of community-based primary healthcare in a rural impoverished region of northern Ghana (Publications)
Ghana's Community-based Health Planning and Services (CHPS) initiative develops accessible healthcare with participatory community support, using strategies developed and tested by a project of the Na
A systematic review of supportive supervision as a strategy to improve primary healthcare services in sub-Saharan Africa (Publications)
BACKGROUND: It may be assumed that supportive supervision effectively builds capacity, improves the quality of care provided by frontline health workers, and positively impacts clinical outcomes. Evid
Immune reconstitution inflammatory syndrome associated with dermatophytoses in two HIV-1 positive patients in rural Tanzania: a case report (Publications)
BACKGROUND: Immune reconstitution inflammatory syndrome associated with dermatophytoses (tinea-IRIS) may cause considerable morbidity. Yet, it has been scarcely reported and is rarely considered in th
