Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels (Publications)
Several infrequent genetic polymorphisms in the SERPINA1 gene are known to substantially reduce concentration of alpha1-antitrypsin (AAT) in the blood. Since low AAT serum levels fail to protect pulmo
Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function (Publications)
BACKGROUND: Genome-wide association studies (GWAS) have identified numerous loci influencing cross-sectional lung function, but less is known about genes influencing longitudinal change in lung functi
Variability of reproductive history across the Swiss SAPALDIA cohort - Pattern and main determinants (Publications)
Background: Reproductive characteristics play an aetiological role for many diseases, including reproductive cancers. They have been shown to vary internationally and nationally, but have not yet been
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis (Publications)
Genetic association studies have identified 21 loci associated with atopic dermatitis risk predominantly in populations of European ancestry. To identify further susceptibility loci for this common, c
Improved air quality and attenuated lung function decline: modification by obesity in the SAPALDIA cohort (Publications)
OBJECTIVE: Air pollution and obesity are hypothesized to contribute to accelerated lung function decline with age through their inflammatory properties. We investigated whether the previously reported
Effectiveness and equity of the Tanzania National Voucher Scheme for mosquito nets over 10 years of implementation (Publications)
BACKGROUND: The Tanzania National Voucher Scheme (TNVS) was a public private partnership managed by the Ministry of Health that provided pregnant women and infants with highly subsidized (long-lasting
Does systemic lidocaine reduce ketamine requirements for endotracheal intubation in calves? (Publications)
OBJECTIVE: To investigate whether an intravenous (IV) lidocaine bolus in calves premedicated with xylazine-butorphanol reduces the amount of ketamine required to allow endotracheal intubation. STUDY D