Community-based prevalence of typhoid fever, typhus, brucellosis and malaria among symptomatic individuals in Afar Region, Ethiopia (Publications)
650 suspected individuals for malaria, 16 (2.5%) were found positive for P. falciparum infection. CONCLUSION: In this study, typhoid fever, typhus, brucellosis and malaria were observed among symptomatic [...] scarcity of proper diagnostic tools, febrile illness related symptoms are often misdiagnosed as malaria. Information on causative agents of febrile illness related symptoms among pastoral communities in [...] based cross-sectional survey, we assessed the prevalence of typhoid fever,...
Efficacy of artemether-lumefantrine and dihydroartemisinin-piperaquine for the treatment of uncomplicated malaria in Papua New Guinea (Publications)
dihydroartemisinin-piperaquine (DHA-PPQ) as the first- and second-line treatments for uncomplicated malaria, respectively. This study was conducted to assess the efficacy of both drugs following adoption of [...] CONCLUSIONS: AL and DHA-PPQ were efficacious as first- and second-line treatments for uncomplicated malaria in PNG. Continued in vivo efficacy monitoring is warranted considering the threat of resistance to
Safety profile of the RTS,S/AS01 malaria vaccine in infants and children: additional data from a phase III randomized controlled trial in sub-Saharan... (Publications)
RTS,S/AS01 (R3R) or non-malaria control vaccine (C3C), or 3 RTS,S/AS01 doses plus control (R3C). Aggregate safety data were reviewed by a multi-functional team. Severe malaria with Blantyre Coma Score [...] controlled trial (NCT00866619) in sub-Saharan Africa showed RTS,S/AS01 vaccine efficacy against malaria. We now present in-depth safety results from this study. 8922 children (enrolled at 5-17 months)
Two cases of long‑lasting, sub‑microscopic <em>Plasmodium malariae</em> infections in adults from coastal Tanzania (Publications)
BACKGROUND: Malaria is endemic in Tanzania with majority of clinical cases caused by Plasmodium falciparum. Additionally, Plasmodium malariae and Plasmodium ovale spp. are also present and clinical ma [...] caused by P. malariae infections are often characterized by a relatively mild illness with a low number of parasites, which can persist for long periods. In this report, two cases of P. malariae infections [...] study clinical manifestations of P. malariae over 4 months. CASE PRESENTATION:...
Predicting the cost of malaria elimination in the Asia-Pacific (Publications)
decade, the countries of the Asia-Pacific region have made significant progress towards the goal of malaria elimination by the year 2030. It is widely accepted that for the region to meet this goal, an in [...] funding is required. However, robust estimates are needed for the optimal coverage and components of malaria elimination packages and the resources required to implement them. In this collection, a multispecies
Insufficient sensitivity of laser desorption-time of flight mass spectrometry-based detection of hemozoin for malaria screening (Publications)
detection of hemozoin was assessed for its performance characteristics as a rapid screening test for malaria. In spite of good specificity of > 95%, poor sensitivity of 80.2% for microscopically positive samples
