Videographic analysis of flight behaviours of host-seeking <em>Anopheles arabiensis</em> towards BG-Malaria trap (Publications)
The BG-Malaria trap (BGM) is an adaptation of the well-known BG-Sentinel trap (BGS) with greater trapping efficiencies for anopheline and culicine mosquitoes. Its continued optimization requires greater
Theory of reactive interventions in the elimination and control of malaria (Publications)
in maintaining the disease-free state after achieving malaria elimination (through other interventions). CONCLUSION: RCD alone can eliminate malaria in only a very limited range of settings, where transmission [...] BACKGROUND: Reactive case detection (RCD) is an integral part of many malaria control and elimination programmes and can be conceived of as a way of gradually decreasing transmission. However, it is unclear
Modelling reactive case detection strategies for interrupting transmission of <em>Plasmodium falciparum</em> malaria (Publications)
BACKGROUND: As areas move closer to malaria elimination, a combination of limited resources and increasing heterogeneity in case distribution and transmission favour a shift to targeted reactive interventions [...] strategies vary, and it is unclear which are most effective in achieving elimination. METHODS: OpenMalaria, an established individual-based stochastic model, was used to simulate RCD in a Zambia-like setting
Models of effectiveness of interventions against malaria transmitted by <em>Anopheles albimanus</em> (Publications)
BACKGROUND: Most impact prediction of malaria vector control interventions has been based on African vectors. Anopheles albimanus, the main vector in Central America and the Caribbean, has higher intrinsic [...] Hispaniola and intervention effect data from southern Mexico were used to parameterize mathematical malaria models. Indoor residual spraying (IRS), insecticide-treated nets (ITNs), and house-screening were [...] excito-repellency. It also supports the idea that housing improvements have...
Mosquito feeding behavior and how it influences residual malaria transmission across Africa (Publications)
an estimated 10.6 million additional malaria cases annually if universal LLIN and IRS coverage was achieved. Higher outdoor biting diminishes the cases of malaria averted by vector control. This reduction [...] times contribute to residual transmission which determines the maximum effectiveness of current malaria prevention. The likelihood mosquitoes feed outside the time of day when LLINs and IRS can protect [...] estimate the public health impact of outdoor biting across Africa. On average 79%...
Evaluation of the Community-Based Malaria Surveillance and Response in Rwanda (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/evaluation-of-the-community-based-malaria-surveillance-and-response-in-rwanda
sustaining malaria elimination. Today, most of malaria control strategies rely on passive case detection through health facilities and CHWs. This passive case detection forms the foundation of malaria surveillance [...] approach will help Rwanda malaria control program to improve the deployment of interventions, and ultimately sustain the gains in malaria declines towards the achievement of malaria elimination in Rwanda. [...] proportion of malaria infections will not take the attention of...
Spatio-temporal modelling of climate variability and malaria transmission across time scales to assess causality, improve forecasting and strengthen... (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/spatio-temporal-modelling-of-climate-variability-and-malaria-transmission-across-time-scales-to-assess-causality-improve-forecasting-and-strengthen-early-warning
Model-based malaria surveillance that incorporates climate effects is recognised as an adaptation strategy to address the impact of climate variability on malaria outbreaks. Climate is one of the drivers [...] cannot identify causal relations or account for non-linear interactions of malaria drivers. The non-stationarity of the malaria data and the varying impact of predictors across seasons suggested that f [...] understanding of the impact of climate change on the malaria burden by developing...
Genome-wide analysis of variations in Plasmodium falciparum parasites population and their impact on different malaria interventions in Tanzania (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/genome-wide-analysis-of-variations-in-plasmodium-falciparum-parasites-population-and-their-impact-on-different-malaria-interventions-in-tanzania
Malaria affects millions of people globally, and the disease remains one of the major public health problems occurring in most parts of the world, causing thousands of deaths each year, especially among
Sub-national tailoring of malaria interventions in Mozambique (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/sub-national-tailoring-of-malaria-interventions-in-mozambique
Malaria remains a public health problem in Mozambique, with more than 10 million cases confirmed in 2020 ( WHO Malaria Report 2020 ). The Mozambique National Malaria Control Program (NMCP) leads the fight [...] fight against malaria in the country through the development and implementation of National Strategic Plans (NSP). The NSP defines the NMCP strategies for fighting malaria including the interventions selected [...] reviewed i.e. during the Malaria Program Review (MPR). NSPs form the base...
Exploring early sexual differentiation in the malaria parasite Plasmodium falciparum (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/exploring-early-sexual-differentiation-in-the-malaria-parasite-plasmodium-falciparum
Apicomplexa, is the causative agent of the most severe form of malaria in humans. Despite the massive implementation of control interventions, malaria still causes over 200 million clinical cases and half a million [...] million deaths annually. The widespread prevalence of malaria in endemic regions is maintained by a complex yet highly efficient transmission cycle between the human host and mosquito vector. For transmission [...] gametocyte biology will be essential to support the development...
