Differential expression of var gene groups is associated with morbidity caused by <em>Plasmodium falciparum </em>infection in Tanzanian children (Publications)
uncomplicated, and asymptomatic malaria. Transcripts of var group A and B genes were more abundant in patients with severe malaria than in patients with uncomplicated malaria. In general, the transcript [...] abundances of var group A and B genes were higher for children with clinical malaria than for children with asymptomatic infections. The var group C and var1-like transcript abundances were similar between
Distribution of survival times of deliberate <em>Plasmodium falciparum</em> infections in tertiary syphilis patients (Publications)
has important implications for mathematical modelling of malaria, which has for the past century exclusively assumed that the duration of malaria infections has an exponential distribution. It is desirable [...] influences the length of monitoring needed in an intervention programme for eliminating or reducing malaria
The use of the polymerase chain reaction for more sensitive detection of <em>Plasmodium falciparum</em> (Publications)
positive for P. vivax and P. malariae an underlying P. falciparum infection remained undetected by microscopy. The introduction of PCR has opened up new possibilities in malaria diagnosis and research. [...] The prevalence of Plasmodium falciparum in children and adults living in a malaria-endemic area in Papua New Guinea was determined by microscopy and by polymerase chain reaction (PCR). The sensitivity
The use of the polymerase chain reaction for more sensitive detection of <em>Plasmodium falciparum</em> (Publications)
positive for P. vivax and P. malariae an underlying P. falciparum infection remained undetected by microscopy. The introduction of PCR has opened up new possibilities in malaria diagnosis and research. [...] The prevalence of Plasmodium falciparum in children and adults living in a malaria-endemic area in Papua New Guinea was determined by microscopy and by polymerase chain reaction (PCR). The sensitivity
Distribution of survival times of deliberate <em>Plasmodium falciparum</em> infections in tertiary syphilis patients (Publications)
has important implications for mathematical modelling of malaria, which has for the past century exclusively assumed that the duration of malaria infections has an exponential distribution. It is desirable [...] influences the length of monitoring needed in an intervention programme for eliminating or reducing malaria
Claudia Daubenberger Appointed Professor at the University of Basel (News)
https://www.swisstph.ch/de/news/news-detail-1/news/claudia-daubenberger-appointed-professor-at-the-university-of-basel
the Faculty of Science and the Faculty of Medicine. Daubenberger’s research focuses on evaluating malaria vaccine development approaches in sub-Saharan Africa and on understanding the immunology of host-pathogen [...] populations. “Claudia Daubenberger’s research has deepened our understanding of immune responses against malaria and other infectious diseases of poverty, which provides a foundation to develop markers for protection [...] will further intensify research at the interface of...
MOSASWA Modelling Support (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/mosaswa-modelling-support
Indoor Residual Spraying (IRS) by Tchau Tchau Malaria (Goodbye Malaria, TTM) in Southern Mozambique as part of the MOSASWA (Mozambique, South Africa and Eswatini) initiative. The evaluation included three [...] The Global Fund to Fight AIDS, Tuberculosis and Malaria (The Global Fund) has commissioned Swiss TPH to evaluate the impact of the Lubombo Spatial Development Initiative 2 (LSDI2) implementation of Indoor [...] Group to create a connected model with data collated from the region that will...
Intermittent preventive antimalarial treatment for Tanzanian infants: follow-up to age 2 years of a randomised, placebo-controlled trial (Publications)
Stopping antimalarial chemoprophylaxis can be followed by increased risk of malaria, suggesting that it interferes with the development of antimalarial immunity. We report analysis of extended follow-up [...] double-blind trial of intermittent preventive antimalarial treatment in infants. The rate of clinical malaria (events per person-year at risk, starting 1 month after final dose of intermittent treatment) was [...] 36%, 95% CI 11-53). Intermittent treatment produced a sustained reduction in...
Intermittent preventive antimalarial treatment for Tanzanian infants: follow-up to age 2 years of a randomised, placebo-controlled trial (Publications)
Stopping antimalarial chemoprophylaxis can be followed by increased risk of malaria, suggesting that it interferes with the development of antimalarial immunity. We report analysis of extended follow-up [...] double-blind trial of intermittent preventive antimalarial treatment in infants. The rate of clinical malaria (events per person-year at risk, starting 1 month after final dose of intermittent treatment) was [...] 36%, 95% CI 11-53). Intermittent treatment produced a sustained reduction in...
Billy Bauzile (People)
https://www.swisstph.ch/de/staff/profile/people/billy-bauzile
insights to support malaria intervention campaigns, the elaboration of national plans for funding requests, and assess intervention impact that can lead to the elimination of malaria or burden reduction [...] reduction in the country. He also supports the teams in diverse activities, including teaching malaria modeling courses and map visualization.
