Antimalarial benzoheterocyclic 4-aminoquinolines: structure-activity relationship, in vivo evaluation, mechanistic and bioactivation studies (Publications)
A novel class of benzoheterocyclic analogues of amodiaquine designed to avoid toxic reactive metabolite formation was synthesized and evaluated for antiplasmodial activity against K1 (multidrug resist
Exposing concerns about vaccination in low- and middle-income countries: a systematic review (Publications)
OBJECTIVES: Concerns about vaccination lead to under- and no-vaccination. Our objective is to synthesise and expose evidence on individuals' and communities' concerns about vaccination to influence cu
Integrated health messaging for multiple neglected zoonoses: approaches, challenges and opportunities in Morocco (Publications)
Integrating the control of multiple neglected zoonoses at the community-level holds great potential, but critical data is missing to inform the design and implementation of different interventions. In
Mobile health applications for HIV prevention and care in Africa (Publications)
PURPOSE OF REVIEW: More people have mobile phones in Africa than at any point in history. Mobile health (m-health), the use of mobile phones to support the delivery of health services, has expanded in
The extended AT-hook is a novel RNA binding motif (Publications)
The AT-hook has been defined as a DNA binding peptide motif that contains a glycine-arginine-proline (G-R-P) tripeptide core flanked by basic amino acids. Recent reports documented variations in the s
Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188... (Publications)
BACKGROUND: The Global Burden of Disease Study 2013 (GBD 2013) aims to bring together all available epidemiological data using a coherent measurement framework, standardised estimation methods, and tr
Monitoring multiple sclerosis by multimodel evoked potentials: numerically versus ordinally scaled scoring systems (Publications)
OBJECTIVE: To compare the ability of different evoked potential scores (EPS) to monitor and predict the disease course in multiple sclerosis (MS). METHODS: Seventy-two patients with MS or clinically i
Molecular epidemiology of human rhinoviruses and enteroviruses highlights their diversity in sub-Saharan Africa (Publications)
Human rhinoviruses (HRVs) and enteroviruses (HEVs) belong to the Enterovirus genus and are the most frequent cause of infection worldwide, but data on their molecular epidemiology in Africa are scarce