Mansonella perstans-Filariose nach Aufenthalt in Kamerun. 19-jährige Patientin, geboren in Kamerun, seit zehn Jahren in der Schweiz (Publications)
g pain in the lower abdomen, predominantly on the right side. A blood smear tested for presumed malaria showed subperiodic microfilariae of the species Mansonella perstans. The patient was treated with
Statistics in Epidemiology Group | Biostatistics at Swiss TPH (Page)
https://www.swisstph.ch/de/about/eph/biostatistics/statistics-in-epidemiology
analysis of cohorts, and in applications in non-communicable disease and infectious diseases such as malaria. The group runs statistics courses in the Faculty of Science and contributes to postgraduate courses [...] Maximise Universal Access Long-lasting insecticidal nets (LLINs), or bed nets, are the mainstay of malaria control. However, more than 50% of people living in endemic areas are currently unprotected because [...] lifespan. The goal of the ViALLIN MUsAcc project is to develop a...
Synthesis of antimalarial 1,2,4-trioxanes via photooxygenation of a chiral allylic alcohol (Publications)
series of monocyclic and spirobicyclic 1,2,4-trioxanes (5, 6). Two products show significant anti-Malaria activity against Plasmodium falciparum when compared with chloroquine
Synthesis of antimalarial 1,2,4-trioxanes via photooxygenation of a chiral allylic alcohol (Publications)
series of monocyclic and spirobicyclic 1,2,4-trioxanes (5, 6). Two products show significant anti-Malaria activity against Plasmodium falciparum when compared with chloroquine
Bicyclic amido compounds with antiprotozoal activity (Publications)
tested for their activities against the causative organisms of East African trypanosomiasis and malaria tropica. The acylation induced in general loss of antiprotozoal activity, but a single compound showed
Bicyclic amido compounds with antiprotozoal activity (Publications)
tested for their activities against the causative organisms of East African trypanosomiasis and malaria tropica. The acylation induced in general loss of antiprotozoal activity, but a single compound showed
SARs of the antiprotozoal action of 6,7-diaryl-bicyclo[2.2.2]octan-2-ols (Publications)
tested for their activity against the causative organisms of East African sleeping sickness and malaria tropica. Structure activity relationships are discussed
SARs of the antiprotozoal action of 6,7-diaryl-bicyclo[2.2.2]octan-2-ols (Publications)
tested for their activity against the causative organisms of East African sleeping sickness and malaria tropica. Structure activity relationships are discussed
30 Years of R&D Towards New Drugs for Tropical Diseases (Page)
https://www.swisstph.ch/de/impact-stories/30-years-of-rd-towards-new-drugs-for-tropical-diseases
human African trypanosomiasis and schistosomiasis) and other infectious diseases of poverty (e.g. malaria and tuberculosis), there was no choice. As their name implies, neglected tropical diseases and infectious [...] expertise emerged as a game-changer. By collaborating with partners, including Novartis, Medicines for Malaria Venture (MMV) and Drugs for Neglected Diseases initiative (DNDi), Swiss TPH played a vital role in [...] Importantly, three of the eight MDGs pertained to health, and MDG...
The effect of dose on the antimalarial efficacy of artemether-lumefantrine: a systematic review and pooled analysis of individual patient data (Publications)
therapy for malaria, although treatment failures occur in some regions. We investigated the effect of dosing strategy on efficacy in a pooled analysis from trials done in a wide range of malaria-endemic settings [...] dose of artemether-lumefantrine provides reliable efficacy in most patients with uncomplicated malaria. However, therapeutic efficacy was lowest in young children from Asia and young underweight children
