Causes of fever in returning travelers: a European multicenter prospective cohort study (Publications)
diagnostic algorithm was used ensuring a systematic evaluation of all participants. After ruling out malaria, PCRs and serologies for dengue, chikungunya and Zika viruses were performed in all patients presenting
Antiplasmodial activity of a series of 1,3,5-triazine-substituted polyamines (Publications)
some parasitic protozoa and it is proposed that the pathway might also represent a target in the malaria parasite Plasmodium falciparum. A series of 1,3,5-triazine-substituted polyamine analogues were tested
Estimation of the antirelapse efficacy of tafenoquine, using <em>Plasmodium vivax</em> genotyping (Publications)
Plasmodium vivax relapse prevention is a key treatment goal in malaria. Use of P. vivax genotyping in a multicenter, double-blind, randomized, placebo-controlled Phase IIb study in Peru, India, Thailand
Heterochromatin silencing and locus repositioning linked to regulation of virulence genes in <em>Plasmodium falciparum</em> (Publications)
The malaria parasite Plasmodium falciparum undergoes antigenic variation to evade host immune responses through switching expression of variant surface proteins encoded by the var gene family. We demonstrate
Novel nucleoside-based antimalarial compounds (Publications)
The malaria-causing parasite Plasmodium falciparum employs a salvage pathway for the biosynthesis of nucleotides, in contrast to de novo biosynthesis that is utilized by the human host. A series of twenty-two
Mar Velarde (People)
https://www.swisstph.ch/de/staff/profile/people/mar-velarde
worked for two different departments within the World Health Organization (WHO), namely the Global Malaria Programme and the Department of Neglected Tropical Diseases. Since 2018, Mar has been working at
Der neue Swiss TPH Jahresbericht ist da! (News)
https://www.swisstph.ch/de/news/news-detail-1/news/der-neue-swiss-tph-jahresbericht-ist-da
Anwendung neuer Therapien erzielt, zum Beispiel gegen die Schlafkrankheit, die Chagas-Krankheit, Malaria und parasitäre Wurminfektionen. Im Jahr 2023 feierte das Swiss TPH sein 80-jähriges Bestehen. Anlässlich
Diseases and Programmes | Swiss TPH (Page)
https://www.swisstph.ch/de/about/scih/diseases-and-programmes
(ESHIA) in Burkina Faso on the use of genetically modified mosquitoes (GMMs) for future malaria control. Target Malaria - a vector control research collaborative based at Imperial College, London - aims to [...] evaluations; and (iii) poverty-related diseases such as Neglected Tropical Diseases, tuberculosis and malaria. From validation to application and health impact assessment We pay particular attention to “access” [...] to develop genetic technologies to modify mosquitoes to ultimately...
Vector Research and Control (Page)
https://www.swisstph.ch/de/about/eph/vector-biology/vector-research-and-control
2024; Code 204582, 2024;13152:131520M. DOI: 10.1117/12.3029450 Related Topics Malaria More to Explore Dynamical Modelling Malaria Initiative Related Activities Preclinical Research Arthropod Testing Facility [...] particularly important vectors as they spread some of the most devastating infectious diseases such as malaria, dengue fever, West Nile fever or Zika virus infections. Investigation of Vectors and Development [...] Study of a Self-Limiting Nondrive Strain of Genetically Modified...
«Ich bin überzeugt, dass Pharmaunternehmen mehr tun können, als Medikamente herstellen» (Page)
https://www.swisstph.ch/de/impact-stories/i-believe-that-pharmaceutical-companies-can-do-more-than-providing-medicines
Ländern mit niedrigem und mittlerem Einkommen auf den Markt. Wir befassen uns mit Krankheiten wie Malaria, Leishmaniose und Dengue-Fieber, von denen vor allem ärmere Länder und vulnerable Bevölkerungsgruppen [...] . Wir können die Herausforderungen von morgen nicht mit den Mitteln von gestern bewältigen. Bei Malaria, gegen die seit 25 Jahren kein neues Medikament mehr entwickelt wurde, nimmt die Arzneimittelresistenz [...] die wir als globale Gemeinschaft im Kampf gegen Lepra erzielt haben, oder...
