Multilocus haplotypes reveal variable levels of diversity and population structure of <em>Plasmodium falciparum</em> in Papua New Guinea, a region of... (Publications)
falciparum on the coast and in the low-lying inland areas. Local heterogeneity in the epidemiology of malaria suggests that parasites from multiple locations will need to be surveyed to define the population [...] variable genetic diversity and population structure of P. falciparum has important implications for malaria control strategies and warrants further fine scale sampling throughout Papua New Guinea
Design, implementation and evaluation of a national campaign to distribute nine million free LLINs to children under five years of age in Tanzania (Publications)
(LLIN) to every child under five years in Tanzania. METHODS: The ITN Cell, a unit within the National Malaria Control Programme (NMCP), coordinated the campaign on behalf of the Ministry of Health and Social [...] mainland Tanzania, the first region being covered separately during an integrated measles immunization/malaria LLIN distribution in August 2008, and was implemented one zone at a time from March 2009 until May
Attributes of <em>Anopheles gambiae</em> swarms in south central Uganda (Publications)
BACKGROUND: Anopheles gambiae continues to be widespread and an important malaria vector species complex in Uganda. New approaches to malaria vector control are being explored including population suppression
Sub-lethal exposure to chlorfenapyr reduces the probability of developing <em>Plasmodium falciparum</em> parasites in surviving Anopheles mosquitoes (Publications)
BACKGROUND: Pyrethroid resistance in the key malaria vectors threatens the success of pyrethroid-treated nets. To overcome pyrethroid resistance, Interceptor(®) G2 (IG2), a 'first-in-class' dual insecticidal [...] the intensity of the P. falciparum infection. This will likely also contribute to the reduction of malaria in communities beyond the direct killing of mosquitoes.
The non-inferiority of piperonyl-butoxide Yorkool® G3 insecticide-treated nets compared to Olyset®Plus measured by <em>Anopheles arabiensis</em>... (Publications)
efficacy to that of existing standard of care. As part of the WHO Global Malaria Programme (GMP) process of assessment of malaria vector control products, a second-in-class insecticide-treated net (ITN)
Expansion of artemisinin partial resistance mutations and lack of histidine rich protein-2 and -3 deletions in <em>Plasmodium falciparum</em>... (Publications)
BACKGROUND: Emerging artemisinin partial resistance and diagnostic resistance are a threat to malaria control in Africa. Plasmodium falciparum kelch13 (k13) propeller-domain mutations that confer artemisinin [...] provide early detection of partner drug resistance, which would likely compromise control and increase malaria morbidity and mortality in East Africa.
Peri-domestic vector control interventions using attractive targeted sugar baits and push-pull strategies (Publications)
Great challenges to sustained malaria and arbovirus control remain, including transmission by vectors that occur outdoors or outside of sleeping hours, the enormous scale of larval breeding in urban centres [...] finding could potentially be due to the size of these studies, because community-level protection from malaria using removal trapping has been demonstrated.
Trends in weekly reported net use by children during and after rainy season in central Tanzania (Publications)
insecticidal nets (LLINs) is one of the principal interventions to prevent malaria in young children, reducing episodes of malaria by 50% and child deaths by one fifth. Prioritizing young children for net
Comparison of molecular quantification of <em>Plasmodium falciparum</em> gametocytes by <em>Pfs</em>25 qRT-PCR and QT-NASBA in relation to mosquito... (Publications)
BACKGROUND: Quantifying gametocyte densities in natural malaria infections is important to estimate malaria transmission potential. Two molecular methods (Pfs25 mRNA quantitative reverse transcriptase
Operational challenges to continuous LLIN distribution: a qualitative rapid assessment in four countries (Publications)
BACKGROUND: The World Health Organization recommends that long-lasting insecticidal nets (LLINs) for malaria prevention should be distributed continuously through antenatal care (ANC) and the expanded programme [...] participants were included (23 in Kenya, 13 in Malawi, 18 in Mali and 16 in Rwanda), drawn from malaria programmes, ANC and EPI programmes, government logistics units, and partner organizations. Interviews
