Relationship between insecticide resistance profiles in <em>Anopheles gambiae</em> <em>sensu lato</em> and agricultural practices in Côte... (Publications)
BACKGROUND: Insecticide-based malaria vector control is increasingly undermined due to the development of insecticide resistance in mosquitoes. Insecticide resistance may partially be related to the use [...] s between the type of agricultural practices and certain insecticide resistance profiles in the malaria vector An. gambiae s.l. which might arise from the use of pesticides deployed for protecting crops
Pharmacokinetics of ivermectin metabolites and their activity against <em>Anopheles stephensi </em>mosquitoes (Publications)
treat worm infections and ectoparasites including lice and scabies mites. Furthermore, survival of malaria transmitting Anopheles mosquitoes is strongly decreased after feeding on humans recently treated [...] . Currently, mass drug administration of ivermectin is under investigation as a potential novel malaria vector control tool to reduce Plasmodium transmission by mosquitoes. A "post-ivermectin effect" has
<em>Plasmodium falciparum</em> sexual commitment rate variation among clinical isolates and diverse laboratory-adapted lines (Publications)
Asexual blood-stage malaria parasites must produce sexual progeny to infect mosquitoes. It is important to understand the scope and causes of intraspecific variation in sexual commitment rates, particularly [...] variation of this key reproductive trait that likely affects transmission. IMPORTANCE Only sexual-stage malaria parasites are transmitted from human blood to mosquitoes. Thus, it is vital to understand variations
The <em>Plasmodium falciparum</em> histone methyltransferase PfSET10 is dispensable for the regulation of antigenic variation and gene expression in... (Publications)
The malaria parasite Plasmodium falciparum employs antigenic variation of the virulence factor P. falciparum erythrocyte membrane protein 1 (PfEMP1) to escape adaptive immune responses during blood infection [...] for life cycle progression in the mosquito vector or during liver stage development.IMPORTANCEThe malaria parasite Plasmodium falciparum infects hundreds of millions of people every year. To survive and
Der Epidemiologe und Gesundheitsexperte Marcel Tanner erhält Ehrendoktorwürde der Universität Zürich (News)
https://www.swisstph.ch/de/news/news-detail-1/news/der-epidemiologe-und-gesundheitsexperte-marcel-tanner-erhaelt-ehrendoktorwuerde-der-universitaet-zuerich
zahlreichen Forschungsarbeiten der Epidemiologie und Bekämpfung infektiöser Krankheiten (vor allem Malaria). Daneben betreute er im Auftrag der DEZA grosse Gesundheitsprogramme und Forschungsprojekte in [...] ländlichen und städtischen Gebieten von Tansania und Tschad. Er war massgeblich an der Entwicklung von Malaria-Impfstoffen (SPf66, RTS,S) für Afrika beteiligt. Von 1996-1997 und 2009-2010 nahm Marcel Tanner
Medical Services (Page)
https://www.swisstph.ch/de/about/dir/medical-services
and, on behalf of the Federal Office of Public Health (FOPH), provides reference diagnosis for malaria and confirmatory diagnosis for other non-endemic parasitic diseases as part of the surveillance concept
Decreased in vitro susceptibility of <em>Plasmodium falciparum</em> isolates to artesunate, mefloquine, chloroquine, and quinine in Cambodia from 2001... (Publications)
from patients enrolled in therapeutic efficacy studies (TES) conducted by the Cambodian National Malaria Control Program for the routine efficacy monitoring of artemisinin-based combination therapy (ACT)
Anti-malarial ozonides OZ439 and OZ609 tested at clinically relevant compound exposure parameters in a novel ring-stage survival assay (Publications)
BACKGROUND: Drug efficacy against kelch 13 mutant malaria parasites can be determined in vitro with the ring-stage survival assay (RSA). The conventional assay protocol reflects the exposure profile of
Additional blood meals increase sporozoite infection in <em>Anopheles</em> mosquitoes but not <em>Plasmodium falciparum</em> genetic diversity (Publications)
multiple blood meals on the number of P. falciparum genotypes developing from polyclonal natural human malaria infections (field-isolates) remains unexplored. Here, we experimentally infect An. gambiae with P
Inhibition of <em>Plasmodium falciparum</em> Hsp90 contributes to the antimalarial activities of aminoalcohol-carbazoles (Publications)
Malaria caused by the protozoan parasite Plasmodium falciparum (Pf) remains a major public health problem throughout the developing world. One molecular target that should receive more attention is the
