Host-directed therapies for infectious diseases: current status, recent progress, and future prospects (Publications)
functional disability arising from tissue damage. The continuing epidemics of tuberculosis, HIV, malaria, and influenza, and the emergence of novel zoonotic pathogens represent major clinical management
Maurer's clefts, the enigma of <em>Plasmodium falciparum</em> (Publications)
Plasmodium falciparum, the causative agent of malaria, completely remodels the infected human erythrocyte to acquire nutrients and to evade the immune system. For this process, the parasite exports more
Synthesis, inhibition potency, binding mode, and antiprotozoal activities of fluorescent inhibitors of trypanothione reductase based on... (Publications)
sub-micromolar range against Trypanosoma brucei rhodesiense and Trypanosoma cruzi, as well as the malaria parasite Plasmodium falciparum, which lack trypanothione metabolism. The inhibitors exhibit strong
Antiplasmodial and antitrypanosomal activity of new esters and ethers of 4-dialkylaminobicyclo[2.2.2]octan-2-ols (Publications)
suffer from painful application, severe side effects and increasing resistance against these drugs. Malaria tropica kills more than 2 million people every year mainly due to growing drug resistance. 4-Dia
Solid phase synthesis and antiprotozoal evaluation of di- and trisubstituted 5'-carboxamidoadenosine analogues (Publications)
rapid increase of resistance to drugs commonly used in the treatment of tropical diseases such as malaria and African sleeping sickness calls for the prompt development of new safe and efficacious drugs
Indole and benzimidazole bichalcophenes: synthesis, DNA binding and antiparasitic activity (Publications)
their antimicrobial activity against the tropical parasites causing African sleeping sickness and malaria. The dicyanoindoles needed to synthesize the target diamidines were obtained through Stille coupling
Jürg Utzinger wird neuer Präsident der R. Geigy-Stiftung (News)
https://www.swisstph.ch/de/news/news-detail-1/news/juerg-utzinger-wird-neuer-praesident-der-r-geigy-stiftung
e zur Urbanisierung, zu neuen «One-Health»-Ansätzen, zu den weit verbreiteten Armutskrankheiten Malaria, Tuberkulose und auch zu den vernachlässigten Tropenkrankheiten, wie Buruli Ulcerans, Bilharziose
Predictors of residual antimalarial drugs in the blood in community surveys in Tanzania (Publications)
cross-sectional survey was conducted in 2015 in three regions of Tanzania with different levels of malaria endemicity. Interviews were conducted and blood samples collected through household surveys for further
Systems Performance and Monitoring (Page)
https://www.swisstph.ch/de/about/scih/systems-performance-and-monitoring
AIDS, Tuberculosis and Malaria created in 2002 to significantly increase resources to fight the three of the world's most devastating diseases (HIV and AIDS, Tuberculosis, and Malaria), and to direct those [...] adults. Am J Trop Med Hyg . 2023;109(1):138-146. DOI: 10.4269/ajtmh.22-0773 Related Topics HIV / AIDS Malaria Neglected Tropical Diseases (NTDs) Tuberculosis Related Activities Consultancy and Policy Advice
Swiss TPH Awarded Four New Research Grants in Paediatric Health (News)
https://www.swisstph.ch/de/news/news-detail-1/news/swiss-tph-awarded-four-new-research-grants-in-paediatric-health
al Nets to Maximise Universal Access Long-lasting insecticidal nets (LLINs) are the mainstay of malaria control. However, more than 50% of people living in endemic areas are currently unprotected because [...] Health Institute and the Ministry of Health in Tanzania will develop a digital tool enabling national malaria control programs to improve planning for programmatic LLIN distribution, monitoring of LLIN quality [...] mosquito net lifespan will optimise resource use, increase the protection...
