A project testing whether small solar powered electric fans improve comfort inside mosquito nets (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/a-project-testing-whether-small-solar-powered-electric-fans-improve-comfort-inside-mosquito-nets
Background Long-lasting insecticidal nets (LLINs) are ineffective malaria transmission prevention tools if they are unused. Discomfort due to heat is the most commonly reported reason for not using nets [...] price of solar power, fans could improve comfort inside nets and be affordable to populations in malaria endemic areas. Here, results are presented from a pilot randomized controlled cross-over study testing
Prevalence of mutations associated with artemisinin partial resistance and sulfadoxine-pyrimethamine resistance in 13 regions in Tanzania in 2021: a... (Publications)
drugs. METHODS: In this cross-sectional survey, capillary dried blood spots were collected from malaria positive asymptomatic individuals in the community and symptomatic individuals in health facilities [...] target sites, presenting to the health facility for care and treatment of conditions other than malaria, and not providing informed consent. Samples were assessed for antimalarial resistance polymorphisms
<em>In vitro</em> antiplasmodial activity and cytotoxicity of extracts and chromatographic fractions of twigs from <em>Pappea capensi</em>s EckI &... (Publications)
The Vha-Venda people of South Africa use Pappea capensis EckI & Zeyh. (Sapindaceae) twigs to treat malaria and its related symptoms. AIM OF STUDY: The main aim of this study was to evaluate the antiplasmodial [...] in P. capensis twigs. CONCLUSION: The study validates the ethnomedicinal use of P. capensis for malaria treatment. It demonstrated the potential of discovering novel antiplasmodial constituents that could
<em>In vitro</em> antiplasmodial activity and cytotoxicity of extracts and chromatographic fractions of twigs from <em>Pappea capensi</em>s EckI &... (Publications)
The Vha-Venda people of South Africa use Pappea capensis EckI & Zeyh. (Sapindaceae) twigs to treat malaria and its related symptoms. AIM OF STUDY: The main aim of this study was to evaluate the antiplasmodial [...] in P. capensis twigs. CONCLUSION: The study validates the ethnomedicinal use of P. capensis for malaria treatment. It demonstrated the potential of discovering novel antiplasmodial constituents that could
Prevalence of mutations associated with artemisinin partial resistance and sulfadoxine-pyrimethamine resistance in 13 regions in Tanzania in 2021: a... (Publications)
drugs. METHODS: In this cross-sectional survey, capillary dried blood spots were collected from malaria positive asymptomatic individuals in the community and symptomatic individuals in health facilities [...] target sites, presenting to the health facility for care and treatment of conditions other than malaria, and not providing informed consent. Samples were assessed for antimalarial resistance polymorphisms
R. Geigy Award 2024: Cutting-Edge Research to Control Communicable and Non-Communicable Diseases in Côte D’Ivoire (News)
https://www.swisstph.ch/de/news/news-detail-1/news/r-geigy-award-2024-cutting-edge-research-to-control-communicable-and-non-communicable-diseases-in-cote-divoire
Department at Swiss TPH and Member of the Board at the R. Geigy-Foundation. New insecticides to control malaria and dengue fever The research work of Julien Zahouli, Emmanuelle Lisro, Laurence Yao and Marc Adou [...] insecticides to combat disease-transmitting mosquitoes such as Anopheles gambiae (vector of the malaria parasite) and Aedes aegypti (vector of the dengue virus). “Julien Zahouli, Emmanuelle Lisro, Laurence
Vector Biology | Research at Swiss TPH (Page)
https://www.swisstph.ch/de/about/eph/vector-biology
particularly important vectors as they spread some of the most devastating infectious diseases such as malaria, dengue fever, West Nile fever or Zika virus infections. Investigation of Vectors and Development
<em>Schistosoma</em>, other helminth infections, and associated risk factors in preschool-aged children in urban Tanzania (Publications)
and performed medical examinations. We performed full blood cell counts and screened for HIV and malaria. Point-of-care circulating cathodic antigen (POC-CCA), urine filtration, Kato-Katz, FLOTAC, and Baermann
Chemoproteomics validates selective targeting of <em>Plasmodium</em> M1 alanyl aminopeptidase as an antimalarial strategy (Publications)
New antimalarial drug candidates that act via novel mechanisms are urgently needed to combat malaria drug resistance. Here, we describe the multi-omic chemical validation of Plasmodium M1 alanyl metal
<em>In vitro</em> assessment of the pharmacodynamic properties and the partitioning of OZ277/RBx-11160 in cultures of <em>Plasmodium falciparum</em> (Publications)
OBJECTIVES: Using synchronous cultures of Plasmodium falciparum malaria, the stage sensitivity of the parasite to OZ277 (RBx-11160), the first fully synthetic antimalarial peroxide that has entered Phase
