Langzeitstudie über 20 Jahre zeigt: Malariakontrolle bei Kleinkindern rettet Leben bis ins Erwachsenenalter (News)
https://www.swisstph.ch/de/news/news-detail-1/news/langzeitstudie-ueber-20-jahre-zeigt-malariakontrolle-bei-kleinkindern-rettet-leben-bis-ins-erwachsenenalter
einen einzigartigen Einblick in den langfristigen Nutzen einer Malariakontrolle bei Kleinkindern. Malaria forderte im Jahr 2020 mehr als 600’000 Todesopfer und ist besonders für Kinder gefährlich. Die im [...] die Studie aufgenommen, die in den Distrikten Kilombero und Ulanga im ländlichen Tansania, in dem Malaria endemisch ist, geboren wurden. Bis 2003 besuchte ein Erhebungsteam die Kinder alle vier Monate zu
Host cytoskeleton remodeling throughout the blood stages of <em>Plasmodium falciparum</em> (Publications)
asexual intraerythrocytic development of Plasmodium falciparum, causing the most severe form of human malaria, is marked by extensive host cell remodeling. Throughout the processes of invasion, intracellular
Amplicon deep sequencing improves <em>Plasmodium falciparum</em> genotyping in clinical trials of antimalarial drugs (Publications)
Clinical trials monitoring malaria drug resistance require genotyping of recurrent Plasmodium falciparum parasites to distinguish between treatment failure and new infection occurring during the trial
Sustaining LLIN coverage with continuous distribution: the school net programme in Tanzania (Publications)
Most malaria-endemic countries have struggled in the past decade to establish effective national-scale continuous distribution mechanisms for long-lasting insecticidal nets (LLINs). Since the implementation
Search for antiprotozoal activity in herbal medicinal preparations; new natural leads against neglected tropical diseases (Publications)
Sleeping sickness, Chagas disease, Leishmaniasis, and Malaria are infectious diseases caused by unicellular eukaryotic parasites ("protozoans"). The three first mentioned are classified as Neglected Tropical
Cytochrome P450/ABC transporter inhibition simultaneously enhances ivermectin pharmacokinetics in the mammal host and pharmacodynamics in... (Publications)
drugs that kill blood-feeding arthropods, has been proposed as a complementary strategy to reduce malaria transmission. Ivermectin is one of the leading candidates given its excellent safety profile. Here
Genetic validation of <em>Pf</em>FKBP35 as an antimalarial drug target (Publications)
Plasmodium falciparum accounts for the majority of over 600,000 malaria-associated deaths annually. Parasites resistant to nearly all antimalarials have emerged and the need for drugs with alternative
Key contributions by the Swiss Tropical and Public Health Institute towards new and better drugs for tropical diseases (Publications)
clonorchiasis, fascioliasis and opisthorchiasis), human African trypanosomiasis, leishmaniasis, malaria, schistosomiasis, soil-transmitted helminthiasis and tuberculosis. In this article, we show case
Quantifying the evolution and impact of antimalarial drug resistance: drug use, spread of resistance, and drug failure over a 12-year period in Papua... (Publications)
key factor driving drug resistance and reduced treatment effectiveness in Plasmodium falciparum malaria, but there are few formal, quantitative analyses of this process. METHODS. We analyzed drug usage
Monitoring of selected health indicators in children living in a copper mine development area in northwestern Zambia (Publications)
The epidemiology of malaria, anaemia and malnutrition in children is potentially altered in mining development areas. In a copper extraction project in northwestern Zambia, a health impact assessment (HIA)
