Mbandakamine-type naphthylisoquinoline dimers and related alkaloids from the central African liana <em>ancistrocladus ealaensis </em>with... (Publications)
ealaines A-D (11-14). The new mbandakamines C (4) and D (5) showed pronounced activities against the malaria parasite Plasmodium falciparum, and they were likewise found to display strong cytotoxic activities
Amplicon deep sequencing improves <em>Plasmodium falciparum</em> genotyping in clinical trials of antimalarial drugs (Publications)
Clinical trials monitoring malaria drug resistance require genotyping of recurrent Plasmodium falciparum parasites to distinguish between treatment failure and new infection occurring during the trial
Nachruf: Dr. Reinhard Glück (News)
https://www.swisstph.ch/de/news/obituary-dr-reinhard-glueck
hingearbeitet, die bei BernaBiotech entwickelte Virosomen-Technologie für die gemeinsame Entwicklung von Malaria-Impfstoffkandidaten nutzbar zu machen. Die draus entstandenen innovativen wissenschaftlichen Ansätze
A path to cooperation between China and Mongolia towards the control of echinococcosis under the Belt and Road Initiative (Publications)
development goals, especially goal 3, target 3.3: by 2030, end the epidemics of AIDS, tuberculosis, malaria and neglected tropical diseases and combat hepatitis, water-borne diseases and other communicable
Host cytoskeleton remodeling throughout the blood stages of <em>Plasmodium falciparum</em> (Publications)
asexual intraerythrocytic development of Plasmodium falciparum, causing the most severe form of human malaria, is marked by extensive host cell remodeling. Throughout the processes of invasion, intracellular
Bioisosteric ferrocenyl aminoquinoline-benzimidazole hybrids: antimicrobial evaluation and mechanistic insights (Publications)
activity against the chloroquine-sensitive NF54 and multi-drug resistant K1 strains of the human malaria parasite, Plasmodium falciparum. All compounds were active against the two strains, generally showing
Phase III study to compare intravenous with oral iron to treat iron deficiency anaemia (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/phase-iii-study-to-compare-intravenous-with-oral-iron-to-treat-iron-deficiency-anaemia
supply, different perception of medication needs and compliance as well as concomitant diseases like malaria, soil-transmitted helminths, schistosomiasis or HIV. All these factors may influence the efficacy
Sustaining LLIN coverage with continuous distribution: the school net programme in Tanzania (Publications)
Most malaria-endemic countries have struggled in the past decade to establish effective national-scale continuous distribution mechanisms for long-lasting insecticidal nets (LLINs). Since the implementation
Neglected Tropical Diseases: Then and Now (Page)
https://www.swisstph.ch/de/impact-stories/neglected-tropical-diseases-then-and-now
MDGs were health-related, focusing on child and maternal health as well as on combatting “HIV/AIDS, malaria, and other diseases”. The MDG era spurred an unprecedented global health effort, facilitated by a [...] Global Fund, and the creation of product development partnerships (PDPs), such as Medicines for Malaria Venture (MMV), FIND and Drugs for Neglected Diseases initiative (DND i ). The Birth of the Term [...] initial group of 13 to 15 NTDs was similar to that of any of the ‘big three’...
Small-scale field evaluation of PermaNet® Dual (a long-lasting net coated with a mixture of chlorfenapyr and deltamethrin) against... (Publications)
BACKGROUND: Due to the rapid expansion of pyrethroid-resistance in malaria vectors in Africa, Global Plan for Insecticide Resistance Management (GPIRM) has recommended the development of long-lasting [...] populations. PermaNet((R)) Dual thus represents a promising tool, with a high potential to reduce malaria transmission and provide community protection in areas compromised by mosquito vector resistance