Mining Sudanese medicinal plants for antiprotozoal agents (Publications)
by either Chagas disease, African trypansomiasis or leishmaniasis, and more than 200 million by malaria. Most of the currently available drugs have drawbacks in terms of toxicity, limited oral availability
Household factors associated with access to insecticide-treated nets and house modification in Bagamoyo and Ulanga districts, Tanzania (Publications)
campaign. These findings are both lower than the least 80% coverage target of the Tanzania National Malaria Strategic Plan (Tanzania NMSP). In Ulanga, population access to ITNs was 92% (n = 1143) and ITNs
Semi-field evaluation of freestanding transfluthrin passive emanators and the BG sentinel trap as a "push-pull control strategy" against <em>Aedes... (Publications)
push-pull system. Push-pull systems have been shown to reduce house entry and outdoor biting rates of malaria vectors and so have the potential to control other outdoor biting mosquitoes such as Aedes aegypti
CDC light traps underestimate the protective efficacy of an indoor spatial repellent against bites from wild <em>Anopheles arabiensis </em>mosquitoes... (Publications)
BACKGROUND: Methods for evaluating efficacy of core malaria interventions in experimental and operational settings are well established but gaps exist for spatial repellents (SR). The objective of this
Mode of action of synthetic antimalarial peroxides (Publications)
Malaria is one of the most widespread infectious diseases which caused an estimated 212 million cases and 429,000 deaths worldwide in 2015. Today, artemisinin-based combination therapy (ACT), a combination
Burden of soil-transmitted helminth infection in pregnant refugees and migrants on the Thailand-Myanmar border: results from a retrospective cohort (Publications)
is a retrospective review of records from pregnant refugee and migrant women who attended Shoklo Malaria Research Unit antenatal care (ANC) clinics along the Thailand-Myanmar border between July 2013 and
Accelerating towards <em>P. vivax</em> elimination with a novel serological test-and-treat strategy: a modelling case study in Brazil (Publications)
BACKGROUND: Plasmodium vivax malaria is challenging to control and eliminate. Treatment with radical cure drugs fails to target the hidden asymptomatic and hypnozoite reservoirs in populations. PvSeroTAT
Ecological and behavioural risk factors of scrub typhus in central Vietnam: a case-control study (Publications)
tests. This tropical rickettsial illness is increasingly recognized as an important cause of non-malaria acute undifferentiated fever in Asia. This study aimed to investigate behavioural and ecological
Pre-existing partner-drug resistance to artemisinin combination therapies facilitates the emergence and spread of artemisinin resistance: a consensus... (Publications)
artemisinin resistance. Each model simulates 100 000 individuals in a particular transmission setting (malaria prevalence of 1%, 5%, 10%, or 20%) with a daily time step that updates individuals' infection status
Patient variability in the blood-stage dynamics of <em>Plasmodium falciparum </em>captured by clustering historical data (Publications)
(within-host models), and can predict the impact of control strategies that affect the blood-stage of malaria. However, the dynamics of P. falciparum blood-stage infections are highly variable between individuals