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1. Combined approach of backbone amide linking and on-resin n-methylation for the synthesis of bioactive and metabolically stable peptides (Publications)

   Combined approach of backbone amide linking and on-resin n-methylation for the synthesis of bioactive and metabolically stable peptides

   Relevanz:

   Rhabdopeptides are a large class of nonribosomal peptides from the bacteria Xenorhabdus and Photorhabdus with low micromolar activity against different protozoa, which are the causative agents of seve

2. Potent inhibitors of plasmodial serine hydroxymethyltransferase (SHMT) featuring a spirocyclic scaffold (Publications)

   Potent inhibitors of plasmodial serine hydroxymethyltransferase (SHMT) featuring a spirocyclic scaffold

   Relevanz:

   With the discovery that serine hydroxymethyltransferase (SHMT) is a druggable target for antimalarials, the aim of this study was to design novel inhibitors of this key enzyme in the folate biosynthes

3. Anemia in tuberculosis cases and household controls from Tanzania: contribution of disease, coinfections, and the role of hepcidin (Publications)

   Anemia in tuberculosis cases and household controls from Tanzania: contribution of disease, coinfections, and the role of hepcidin

   Relevanz:

   BACKGROUND: Tuberculosis (TB) induces a systemic inflammatory state affecting iron homeostasis. Patients with TB often have additional comorbidities such as anemia which can result in poorer treat out

4. Bayesian estimates of the incidence of rare cancers in Europe (Publications)

   Bayesian estimates of the incidence of rare cancers in Europe

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5. How can we accelerate progress on civil registration and vital statistics? [Editorial] (Publications)

   How can we accelerate progress on civil registration and vital statistics? [Editorial]

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6. Efficacy and tolerability of triple drug therapy with albendazole, pyrantel pamoate, and oxantel pamoate compared with albendazole plus oxantel... (Publications)

   Efficacy and tolerability of triple drug therapy with albendazole, pyrantel pamoate, and oxantel pamoate compared with albendazole plus oxantel pamoate, pyrantel pamoate plus oxantel pamoate, and mebendazole plus pyrantel pamoate and oxantel pamoate again

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7. Rapid MALDI-TOF-based identification of <em>Brucella melitensis </em>from positive blood culture vials may prevent laboratory-acquired infections (Publications)

   Rapid MALDI-TOF-based identification of <em>Brucella melitensis </em>from positive blood culture vials may prevent laboratory-acquired infections

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8. Rapport sur les défis dans le domaine de la vaccination en Suisse (Publications)

   Rapport sur les défis dans le domaine de la vaccination en Suisse

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9. Support to the Swiss Immunisation programme (Publications)

   Support to the Swiss Immunisation programme

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10. Orientia <em>tsutsugamushi</em> is highly susceptible to the RNA polymerase switch region inhibitor corallopyronin a <em>in vitro</em> and<em> in... (Publications)

    Orientia <em>tsutsugamushi</em> is highly susceptible to the RNA polymerase switch region inhibitor corallopyronin a <em>in vitro</em> and<em> in vivo</em>

    Relevanz:

    Scrub typhus is a potentially lethal infection caused by the obligate intracellular bacterium Orientia tsutsugamushi Reports on the emergence of doxycycline-resistant strains highlight the urgent need