First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children (Publications)
Background An ongoing phase 3 study of the efficacy, safety, and immunogenicity of candidate malaria vaccine RTS,S/AS01 is being conducted in seven African countries. Methods From March 2009 through J
Interaction between asthma and smoking increases the risk of adult airway obstruction (Publications)
The aim of the present study was to analyse the interaction between asthma and smoking in the risk of adult airway obstruction, accounting for atopy. In the European Community Respiratory Health Surve
Progress in research, control and elimination of helminth infections in Asia (Publications)
Global health has substantially improved over the past 20 years. In low- and middle-income countries, in particular, great strives have been made in the control of communicable diseases, including hel
Multiparasitism and intensity of helminth infections in relation to symptoms and nutritional status among children: a cross-sectional study in... (Publications)
The occurrence and spatial distribution of intestinal helminth infection in children is fairly well understood. However, knowledge on how helminth infections govern intestinal morbidity is scarce. We
Isothermal microcalorimetry accurately detects bacteria, tumorous microtissues, and parasitic worms in a label-free well-plate assay (Publications)
Isothermal microcalorimetry is a label-free assay that allows monitoring of enzymatic and metabolic activities. The technique has strengths, but most instruments have a low throughput, which has limit
Evolutionary history and global spread of the <em>Mycobacterium tuberculosis</em> Beijing lineage (Publications)
Mycobacterium tuberculosis strains of the Beijing lineage are globally distributed and are associated with the massive spread of multidrug-resistant (MDR) tuberculosis in Eurasia. Here we reconstructe
Antiprotozoal activity and DNA binding of dicationic acridones (Publications)
Dicationic acridone derivatives were synthesized and their antiparasitic activity was evaluated. Acridones displayed in vitro nanomolar IC50 values against Trypanosoma brucei rhodesiense STIB900 with