Publications
Alchalabi L, Schaffner E, Imboden M, Difloe-Geisert J.C, Zitzmann N.U, Probst-Hensch N. Removable dental prostheses and difficulties with chewing among frail individuals: results from the Swiss SAPALDIA cohort. Swiss Dent J. 2024;134(2):53-71. DOI: 10.61872/sdj-2024-02-04
Probst-Hensch N, Imboden M, Jeong A, Keidel D, Vermes T, Witzig M, Cullati S, Tancredi S, Noor N, Rodondi P.Y, Harju E, Michel G, Frank I, Kahlert C, Cusini A, Rodondi N, Chocano-Bedoya P.O, Bardoczi J.B, Stuber M.J, Vollrath F, Fehr J, Frei A, Kaufmann M, Geigges M, von Wyl V, Puhan M.A, Albanese E, Crivelli L, Lovison G.F, Corona Immunitas Research Group. Long-term trajectories of densely reported depressive symptoms during an extended period of the COVID-19 pandemic in Switzerland: social worries matter. Compr Psychiatry. 2024;130:152457. DOI: 10.1016/j.comppsych.2024.152457
Shrine N, Guyatt A.L, Erzurumluoglu A.M, Jackson V.E, Hobbs B.D, Melbourne C.A, Batini C, Fawcett K.A, Song K, Sakornsakolpat P, Li X, Boxall R, Reeve N.F, Obeidat M, Zhao J.H, Wielscher M, Weiss S, Kentistou K.A, Cook J.P, Sun B.B, Zhou J, Hui J, Karrasch S, Imboden M, Harris S.E, Marten J, Enroth S, Kerr S.M, Surakka I, Vitart V, Lehtimäki T, Allen R.J, Bakke P.S, Beaty T.H, Bleecker E.R, Bossé Y, Brandsma C.A, Chen Z, Crapo J.D, Danesh J, DeMeo D.L, Dudbridge F, Ewert R, Gieger C, Gulsvik A, Hansell A.L, Hao K, Hoffman J.D, Hokanson J.E, Homuth G, Joshi P.K, Joubert P, Langenberg C, Li X, Li L, Lin K, Lind L, Locantore N, Luan J, Mahajan A, Maranville J.C, Murray A, Nickle D.C, Packer R, Parker M.M, Paynton M.L, Porteous D.J, Prokopenko D, Qiao D, Rawal R, Runz H, Sayers I, Sin D.D, Smith B.H, Artigas M.S, Sparrow D, Tal-Singer R, Timmers Prhj, Van den Berge M, Whittaker J.C, Woodruff P.G, Yerges-Armstrong L.M, Troyanskaya O.G, Raitakari O.T, Kähönen M, Polašek O, Gyllensten U, Rudan I, Deary I.J, Probst-Hensch N.M, Schulz H, James A.L, Wilson J.F, Stubbe B, Zeggini E, Jarvelin M.R, Wareham N, Silverman E.K, Hayward C, Morris A.P, Butterworth A.S, Scott R.A, Walters R.G, Meyers D.A, Cho M.H, Strachan D.P, Hall I.P, Tobin M.D, Wain L.V. Author correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. Nat Genet. 2024;56(5):1032-1033. DOI: 10.1038/s41588-024-01752-4
Tancredi S, van der Linden B.W.A, Chiolero A, Cullati S, Imboden M, Probst-Hensch N, Keidel D, Witzig M, Dratva J, Michel G, Harju E, Frank I, Lorthe E, Baysson H, Stringhini S, Kahlert C.R, Bardoczi J.B, Haller M.L, Chocano-Bedoya P.O, Rodondi N, Amati R, Albanese E, Corna L, Crivelli L, Kaufmann M, Frei A, von Wyl V. Socioeconomic status and adherence to preventive measures during the COVID-19 pandemic in Switzerland: a population based digital cohort analysis. Int J Public Health. 2024;69:1606861. DOI: 10.3389/ijph.2024.1606861
Zhai J, Voraphani N, Imboden M, Keidel D, Liu C, Stern D.A, Venker C, Petersen H, Bosco A, Sherrill D.L, Morgan W.J, Tesfaigzi Y, Probst-Hensch N.M, Martinez F.D, Halonen M, Guerra S. Circulating biomarkers of airflow limitation across the life span. J Allergy Clin Immunol. 2024;153(6):1692-1703. DOI: 10.1016/j.jaci.2023.12.026
Budu-Aggrey A, Kilanowski A, Sobczyk M.K, Shringarpure S.S, Mitchell R, Reis K, Reigo A, Mägi R, Nelis M, Tanaka N, Brumpton B.M, Thomas L.F, Sole-Navais P, Flatley C, Espuela-Ortiz A, Herrera-Luis E, Lominchar J.V.T, Bork-Jensen J, Marenholz I, Arnau-Soler A, Jeong A, Fawcett K.A, Baurecht H, Rodriguez E, Alves A.C, Kumar A, Sleiman P.M, Chang X, Medina-Gomez C, Hu C, Xu C.J, Qi C, El-Heis S, Titcombe P, Antoun E, Fadista J, Wang C.A, Thiering E, Wu B, Kress S, Kothalawala D.M, Kadalayil L, Duan J, Zhang H, Hadebe S, Hoffmann T, Jorgenson E, Choquet H, Risch N, Njølstad P, Andreassen O.A, Johansson S, Almqvist C, Gong T, Ullemar V, Karlsson R, Magnusson P.K.E, Szwajda A, Burchard E.G, Thyssen J.P, Hansen T, Kårhus L.L, Dantoft T.M, Jeanrenaud Acsn, Ghauri A, Arnold A, Homuth G, Lau S, Nöthen M.M, Hübner N, Imboden M, Visconti A, Falchi M, Bataille V, Hysi P, Ballardini N, Boomsma D.I, Hottenga J.J, Müller-Nurasyid M, Ahluwalia T.S, Stokholm J, Chawes B, Schoos A.M, Esplugues A, Bustamante M, Raby B, Arshad S, German C, Esko T, Milani L.A, Metspalu A, Terao C, Abuabara K, Løset M, Hveem K, Jacobsson B, Pino-Yanes M, Strachan D.P, Grarup N, Linneberg A, Lee Y.A, Probst-Hensch N, Weidinger S, Jarvelin M.R, Melén E, Hakonarson H, Irvine A.D, Jarvis D, Nijsten T, Duijts L, Vonk J.M, Koppelmann G.H, Godfrey K.M, Barton S.J, Feenstra B, Pennell C.E, Sly P.D, Holt P.G, Williams L.K, Bisgaard H, Bønnelykke K, Curtin J, Simpson A, Murray C, Schikowski T, Bunyavanich S, Weiss S.T, Holloway J.W, Min J.L, Brown S.J, Standl M, Paternoster L. European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation. Nat Commun. 2023;14:6172. DOI: 10.1038/s41467-023-41180-2
Daniore P, Moser A, Höglinger M, Probst-Hensch N, Imboden M, Vermes T, Keidel D, Bochud M, Ortega Herrero N, Baggio S, Chocano-Bedoya P, Rodondi N, Tancredi S, Wagner C, Cullati S, Stringhini S, Gonseth Nusslé S, Veys-Takeuchi C, Zuppinger C, Harju E, Michel G, Frank I, Kahlert C.R, Albanese E, Crivelli L, Levati S, Amati R, Kaufmann M, Geigges M, Ballouz T, Frei A, Fehr J, von Wyl V. Interplay of digital proximity app use and SARS-CoV-2 vaccine uptake in Switzerland: analysis of two population-based cohort studies. Int J Public Health. 2023;68:1605812. DOI: 10.3389/ijph.2023.1605812
Govarts E, Gilles L, Rodriguez Martin L, Santonen T, Apel P, Alvito P, Anastasi E, Andersen H.R, Andersson A.M, Andryskova L, Antignac J.P, Appenzeller B, Barbone F, Barnett-Itzhaki Z, Barouki R, Berman T, Bil W, Borges T, Buekers J, Cañas-Portilla A, Covaci A, Csako Z, Den Hond E, Dvorakova D, Fabelova L, Fletcher T, Frederiksen H, Gabriel C, Ganzleben C, Göen T, Halldorsson T.I, Haug L.S, Horvat M, Huuskonen P, Imboden M, Jagodic Hudobivnik M, Janasik B, Janev Holcer N, Karakitsios S, Katsonouri A, Klanova J, Kokaraki V, Kold Jensen T, Koponen J, Laeremans M, Laguzzi F, Lange R, Lemke N, Lignell S, Lindroos A.K, Lobo Vicente J, Luijten M, Makris K.C, Mazej D, Melymuk L, Meslin M, Mol H, Montazeri P, Murawski A, Namorado S, Niemann L, Nubler S, Nunes B, Olafsdottir K, Palkovicova Murinova L, Papaioannou N, Pedraza-Diaz S, Piler P, Plichta V, Poteser M, Probst-Hensch N, Rambaud L, Rauscher-Gabernig E, Rausova K, Remy S, Riou M, Rosolen V, Rousselle C, Ruther M, Sarigiannis D, Silva M.J, Šlejkovec Z, Snoj Tratnik J, Stajnko A, Szigeti T, Tarazona J.V, Thomsen C, Tkalec Z, Tolonen H, Trnovec T, Uhl M, Van Nieuwenhuyse A, Vasco E, Verheyen V.J, Viegas S, Vinggaard A.M, Vogel N, Vorkamp K, Wasowicz W, Weber T, Wimmerova S, Woutersen M, Zimmermann P, Zvonar M, Koch H, Kolossa-Gehring M, Esteban López M, Castaño A, Stewart L, Sepai O, Schoeters G. Harmonized human biomonitoring in European children, teenagers and adults: EU-wide exposure data of 11 chemical substance groups from the HBM4EU Aligned Studies (2014-2021). Int J Hyg Environ Health. 2023;249:114119. DOI: 10.1016/j.ijheh.2023.114119
Guyatt A, John C, Williams A.T, Shrine N, Reeve N.F, SpiroMeta Consortium, Sayers I, Hall I, Wain L.V, Sheehan N, Dudbridge F, Tobin M.D. Mendelian randomisation of eosinophils and other cell types in relation to lung function and disease. Thorax. 2023;78(5):496-503. DOI: 10.1136/thoraxjnl-2021-217993
Harju E, Speierer A, Jungo K.T, Levati S, Baggio S, Tancredi S, Noor N, Rodondi P.Y, Cullati S, Imboden M, Keidel D, Witzig M, Frank I, Kohler P, Kahlert C, Crivelli L, Amati R, Albanese E, Kaufmann M, Frei A, Von Wyl V, Puhan M.A, Probst-Hensch N, Michel G, Rodondi N, Chocano-Bedoya P, Corona Immunitas Res Grp. Changes in healthcare utilization during the COVID-19 pandemic and potential causes : a cohort study from Switzerland. Int J Public Health. 2023;68:1606010. DOI: 10.3389/ijph.2023.1606010
Oosterwegel M.J, Ibi D, Portengen L, Probst-Hensch N, Tarallo S, Naccarati A, Imboden M, Jeong A, Robinot N, Scalbert A, Amaral A.F.S, van Nunen E, Gulliver J, Chadeau-Hyam M, Vineis P, Vermeulen R, Keski-Rahkonen P, Vlaanderen J. Variability of the human serum metabolome over 3 months in the EXPOsOMICS Personal Exposure Monitoring study. Environ Sci Technol. 2023;57(34):12752-12759. DOI: 10.1021/acs.est.3c03233
Ottenbros I.B, Ammann P, Imboden M, Fuhrimann S, Zock J.P, Lebret E, Vermeulen R.C.H, Nijssen R, Lommen A, Mol H, Vlaanderen J.J, Probst-Hensch N. Urinary pesticide mixture patterns and exposure determinants in the adult population from the Netherlands and Switzerland: application of a suspect screening approach. Environ Res. 2023;239(Pt 1):117216. DOI: 10.1016/j.envres.2023.117216
Probst-Hensch N, Jeong A, Keidel D, Imboden M, Lovison G. Depression trajectories during the COVID-19 pandemic in the high-quality health care setting of Switzerland: the COVCO-Basel cohort. Public Health. 2023;217:65-73. DOI: 10.1016/j.puhe.2023.01.010
Rodriguez Martin L, Gilles L, Helte E, Åkesson A, Tägt J, Covaci A, Sakhi A.K, Van Nieuwenhuyse A, Katsonouri A, Andersson A.M, Gutleb A.C, Janasik B, Appenzeller B, Gabriel C, Thomsen C, Mazej D, Sarigiannis D, Anastasi E, Barbone F, Tolonen H, Frederiksen H, Klanova J, Koponen J, Tratnik J.S, Pack K, Gudrun K, Ólafsdóttir K, Knudsen L.E, Rambaud L, Strumylaite L, Murinova L.P, Fabelova L, Riou M, Berglund M, Szabados M, Imboden M, Laeremans M, Eštóková M, Janev Holcer N, Probst-Hensch N, Vodrazkova N, Vogel N, Piler P, Schmidt P, Lange R, Namorado S, Kozepesy S, Szigeti T, Halldorsson T.I, Weber T, Jensen T.K, Rosolen V, Puklova V, Wasowicz W, Sepai O, Stewart L, Kolossa-Gehring M, Esteban-López M, Castaño A, Bessems J, Schoeters G, Govarts E. Time patterns in internal human exposure data to bisphenols, phthalates, DINCH, organophosphate flame retardants, cadmium and polyaromatic hydrocarbons in Europe. Toxics. 2023;11(10):819. DOI: 10.3390/toxics11100819
Sabatini S, Kaufmann M, Fadda M, Tancredi S, Noor N, Van Der Linden B.W.A, Cullati S, Frank I, Michel G, Harju E, Luedi C, Frei A, Ballouz T, Menges D, Fehr J, Kohler P, Kahlert C.R, Scheu V, Ortega N, Chocano-Bedoya P, Rodondi N, Stringhini S, Baysson H, Lorthe E, Zufferey M.C, Suggs L.S, Albanese E, Vincentini J, Bochud M, D'Acremont V, Nusslé S.G, Imboden M, Keidel D, Witzig M, Probst-Hensch N, von Wyl V. Factors associated with COVID-19 non-vaccination in Switzerland: a nationwide study. Int J Public Health. 2023;68:1605852. DOI: 10.3389/ijph.2023.1605852
Shrine N, Izquierdo A.G, Chen J, Packer R, Hall R.J, Guyatt A.L, Batini C, Thompson R.J, Pavuluri C, Malik V, Hobbs B.D, Moll M, Kim W, Tal-Singer R, Bakke P, Fawcett K.A, John C, Coley K, Piga N.N, Pozarickij A, Lin K, Millwood I.Y, Chen Z, Li L, China Kadoorie Biobank Collaborative Group, Wijnant S.R.A, Lahousse L, Brusselle G, Uitterlinden A.G, Manichaikul A, Oelsner E.C, Rich S.S, Barr R.G, Kerr S.M, Vitart V, Brown M.R, Wielscher M, Imboden M, Jeong A, Bartz T.M, Gharib S.A, Flexeder C, Karrasch S, Gieger C, Peters A, Stubbe B, Hu X, Ortega V.E, Meyers D.A, Bleecker E.R, Gabriel S.B, Gupta N, Smith A.V, Luan J, Zhao J.H, Hansen A.F, Langhammer A, Willer C, Bhatta L, Porteous D, Smith B.H, Campbell A, Sofer T, Lee J, Daviglus M.L, Yu B, Lim E, Xu H, O'Connor G.T, Thareja G, Albagha O.M.E, Qatar Genome Program Research (QGPR) Consortium, Suhre K, Granell R, Faquih T.O, Hiemstra P.S, Slats A.M, Mullin B.H, Hui J, James A, Beilby J, Patasova K, Hysi P, Koskela J.T, Wyss A.B, Jin J, Sikdar S, Lee M, May-Wilson S, Pirastu N, Kentistou K.A, Joshi P.K, Timmers Prhj, Williams A.T, Free R.C, Wang X, Morrison J.L, Gilliland F.D, Chen Z, Wang C.A, Foong R.E, Harris S.E, Taylor A, Redmond P, Cook J.P, Mahajan A, Lind L, Palviainen T, Lehtimäki T, Raitakari O.T, Kaprio J, Rantanen T, Pietiläinen K.H, Cox S.R, Pennell C.E, Hall G.L, Gauderman W.J, Brightling C, Wilson J.F, Vasankari T, Laitinen T, Salomaa V, Mook-Kanamori D.O, Timpson N.J, Zeggini E, Dupuis J, Hayward C, Brumpton B, Langenberg C, Weiss S, Homuth G, Schmidt C.O, Probst-Hensch N, Jarvelin M.R, Morrison A.C, Polasek O, Rudan I, Lee J.H, Sayers I, Rawlins E.L, Dudbridge F, Silverman E.K, Strachan D.P, Walters R.G, Morris A.P, London S.J, Cho M.H, Wain L.V, Hall I.P, Tobin M.D. Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk. Nat Genet. 2023;55(3):410-422. DOI: 10.1038/s41588-023-01314-0
Shrine N, Izquierdo A.G, Chen J, Packer R, Hall R.J, Guyatt A.L, Batini C, Thompson R.J, Pavuluri C, Malik V, Hobbs B.D, Moll M, Kim W, Tal-Singer R, Bakke P, Fawcett K.A, John C, Coley K, Piga N.N, Pozarickij A, Lin K, Millwood I.Y, Chen Z, Li L, Wijnant S.R.A, Lahousse L, Brusselle G, Uitterlinden A.G, Manichaikul A, Oelsner E.C, Rich S.S, Barr R.G, Kerr S.M, Vitart V, Brown M.R, Wielscher M, Imboden M, Jeong A, Bartz T.M, Gharib S.A, Flexeder C, Karrasch S, Gieger C, Peters A, Stubbe B, Hu X, Ortega V.E, Meyers D.A, Bleecker E.R, Gabriel S.B, Gupta N, Smith A.V, Luan J, Zhao J.H, Hansen A.F, Langhammer A, Willer C, Bhatta L, Porteous D, Smith B.H, Campbell A, Sofer T, Lee J, Daviglus M.L, Yu B, Lim E, Xu H, O'Connor G.T, Thareja G, Albagha O.M.E, Suhre K, Granell R, Faquih T.O, Hiemstra P.S, Slats A.M, Mullin B.H, Hui J, James A, Beilby J, Patasova K, Hysi P, Koskela J.T, Wyss A.B, Jin J, Sikdar S, Lee M, May-Wilson S, Pirastu N, Kentistou K.A, Joshi P.K, Timmers Prhj, Williams A.T, Free R.C, Wang X, Morrison J.L, Gilliland F.D, Chen Z, Wang C.A, Foong R.E, Harris S.E, Taylor A, Redmond P, Cook J.P, Mahajan A, Lind L, Palviainen T, Lehtimäki T, Raitakari O.T, Kaprio J, Rantanen T, Pietiläinen K.H, Cox S.R, Pennell C.E, Hall G.L, Gauderman W.J, Brightling C, Wilson J.F, Vasankari T, Laitinen T, Salomaa V, Mook-Kanamori D.O, Timpson N.J, Zeggini E, Dupuis J, Hayward C, Brumpton B, Langenberg C, Weiss S, Homuth G, Schmidt C.O, Probst-Hensch N, Jarvelin M.R, Morrison A.C, Polasek O, Rudan I, Lee J.H, Sayers I, Rawlins E.L, Dudbridge F, Silverman E.K, Strachan D.P, Walters R.G, Morris A.P, London S.J, Cho M.H, Wain L.V, Hall I.P, Tobin M.D. Author correction: Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk. Nat Genet. 2023;55(10):1778-1779. DOI: 10.1038/s41588-023-01531-7
Tancredi S, Chiolero A, Wagner C, Haller M.L, Chocano-Bedoya P, Ortega N, Rodondi N, Kaufmann L, Lorthe E, Baysson H, Stringhini S, Michel G, Ludi C, Harju E, Frank I, Imboden M, Witzig M, Keidel D, Probst-Hensch N, Amati R, Albanese E, Corna L, Crivelli L, Vincentini J, Gonseth Nussle S, Bochud M, D'Acremont V, Kohler P, Kahlert C.R, Cusini A, Frei A, Puhan M.A, Geigges M, Kaufmann M, Fehr J, Cullati S, Corona Immunitas Research Group. Seroprevalence trends of anti-SARS-CoV-2 antibodies and associated risk factors: a population-based study. Infection. 2023;51(5):1453-1465. DOI: 10.1007/s15010-023-02011-0
Tancredi S, Ulyte A, Wagner C, Keidel D, Witzig M, Imboden M, Probst-Hensch N, Amati R, Albanese E, Levati S, Crivelli L, Kohler P, Cusini A, Kahlert C, Harju E, Michel G, Ludi C, Ortega N, Baggio S, Chocano-Bedoya P, Rodondi N, Ballouz T, Frei A, Kaufmann M, Von Wyl V, Lorthe E, Baysson H, Stringhini S, Schneider V, Kaufmann L, Wieber F, Volken T, Zysset A, Dratva J, Cullati S, Corona Immunitas Research Group. Changes in socioeconomic resources and mental health after the second COVID-19 wave (2020-2021): a longitudinal study in Switzerland. Int J Equity Health. 2023;22:51. DOI: 10.1186/s12939-023-01853-2
Jeong A, Eze I.C, Vienneau D, de Hoogh K, Keidel D, Rothe T, Burdet L, Holloway J.W, Jarvis D, Kronenberg F, Lovison G, Imboden M, Probst-Hensch N. Residential greenness-related DNA methylation changes. Environ Int. 2022;158:106945. DOI: 10.1016/j.envint.2021.106945
Jeong A, Galliker F, Imboden M, Keidel D, de Hoogh K, Vienneau D, Siegrist M, Crivelli L, Lovison G, Probst-Hensch N. Residential exposure to greenspace and life satisfaction in times of COVID-19: a cross-sectional analysis of 9444 participants from a population-based study in Basel-Stadt and Basel-Landschaft. Swiss Med Wkly. 2022;152:w30204. DOI: 10.4414/smw.2022.w30204
Obas K.A, Kwiatkowski M, Schaffner E, Lang U.E, Stolz D, Eze I.C, Imboden M, Probst-Hensch N. Depression and cardiovascular disease are not linked by high blood pressure: findings from the SAPALDIA cohort. Sci Rep. 2022;12:5516. DOI: 10.1038/s41598-022-09396-2
Sanchez D, Jeong A, Essé C, Bassa F.K, Koné S, Acka F, Laubhouet-Koffi V, Kouassi D, Utzinger J, N'Goran E.K, Bonfoh B, Imboden M, Holloway J.W, Eze I.C. Validity and cardio-metabolic risk profiles of DNA methylation clocks among adults in south-central Côte d’Ivoire. Epigenetics Commun. 2022;2:1. DOI: 10.1186/s43682-022-00008-8
Journal Article
Speierer A, Chocano-Bedoya P.O, Anker D, Schmid A, Keidel D, Vermes T, Imboden M, Levati S, Franscella G, Corna L, Amati R, Harju E, Luedi C, Michel G, Veys-Takeuchi C, Zuppinger C, Nussle S.G, D'Acremont V, Tall I, Salberg E, Baysson H, Lorthe E, Pennacchio F, Frei A, Kaufmann M, Geigges M, West E.A, Schwab N, Cullati S, Chiolero A, Kahlert C, Stringhini S, Vollrath F, Probst-Hensch N, Rodondi N, Puhan M.A, von Wyl V. The Corona Immunitas Digital Follow-Up eCohort to monitor impacts of the SARS-CoV-2 pandemic in Switzerland: study protocol and first results. Int J Public Health. 2022;67:1604506. DOI: 10.3389/ijph.2022.1604506
Thériault S, Imboden M, Biggs M.L, Austin T.R, Aeschbacher S, Schaffner E, Brody J.A, Bartz T.M, Risch M, Grossmann K, Lin H.J, Soliman E.Z, Post W.S, Risch L, Krieger J.E, Pereira A.C, Heckbert S.R, Sotoodehnia N, Probst-Hensch N.M, Conen D. Genome-wide analyses identify SCN5A as a susceptibility locus for premature atrial contraction frequency. iScience. 2022;25(10):105210. DOI: 10.1016/j.isci.2022.105210
Cerletti P, Eze I.C, Keidel D, Schaffner E, Stolz D, Gasche-Soccal P.M, Rothe T, Imboden M, Probst-Hensch N. Perceived built environment, health-related quality of life and health care utilization. PLoS One. 2021;16(5):e0251251. DOI: 10.1371/journal.pone.0251251
Keidel D, Vermes T, Witzig M, Jeong A, Galliker F, Tertemiz E, Schaffner E, de Hoogh K, Pärli K, Lovison G, Imboden M, Probst-Hensch N. COVCO-Basel - Corona Immunitas: Wissenschaftlicher Schlussbericht - Juli 2020 bis August 2021. Basel: Swiss Tropical and Public Health Institute, 2021
Report
McCartney D.L, Min J.L, Richmond R.C, Lu A.T, Sobczyk M.K, Davies G, Broer L, Guo X, Jeong A, Jung J, Kasela S, Katrinli S, Kuo P.L, Matias-Garcia P.R, Mishra P.P, Nygaard M, Palviainen T, Patki A, Raffield L.M, Ratliff S.M, Richardson T.G, Robinson O, Soerensen M, Sun D, Tsai P.C, van der Zee M.D, Walker R.M, Wang X, Wang Y, Xia R, Xu Z, Yao J, Zhao W, Correa A, Boerwinkle E, Dugue P.A, Durda P, Elliott H.R, Gieger C, Genetics of DNA Methylation Consortium, de Geus E.J.C, Harris S.E, Hemani G, Imboden M, Kahonen M, Kardia S.L.R, Kresovich J.K, Li S, Lunetta K.L, Mangino M, Mason D, McIntosh A.M, Mengel-From J, Moore A.Z, Murabito J.M, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Ollikainen M, Pankow J.S, Pedersen N.L, Peters A, Polidoro S, Porteous D.J, Raitakari O, Rich S.S, Sandler D.P, Sillanpaa E, Smith A.K, Southey M.C, Strauch K, Tiwari H, Tanaka T, Tillin T, Uitterlinden A.G, Van Den Berg D.J, van Dongen J, Wilson J.G, Wright J, Yet I, Arnett D, Bandinelli S, Bell J.T, Binder A.M, Boomsma D.I, Chen W, Christensen K, Conneely K.N, Elliott P, Ferrucci L, Fornage M, Hagg S, Hayward C, Irvin M, Kaprio J, Lawlor D.A, Lehtimaki T, Lohoff F.W, Milani L, Milne R.L, Probst-Hensch N, Reiner A.P, Ritz B, Rotter J.I, Smith J.A, Taylor J.A, van Meurs J.B.J, Vineis P, Waldenberger M, Deary I.J, Relton C.L, Horvath S, Marioni R.E. Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. Genome Biol. 2021;22:194. (TOPMed). DOI: 10.1186/s13059-021-02398-9
Probst-Hensch N, Jeong A, Stolz D, Pons M, Soccal P.M, Bettschart R, Jarvis D, Holloway J.W, Kronenberg F, Imboden M, Schindler C, Lovison G.F. Causal effects of body mass index on airflow obstruction and forced mid-expiratory flow: a Mendelian randomization study taking interactions and age-specific instruments into consideration toward a life course perspective. Front Public Health. 2021;9:584955. DOI: 10.3389/fpubh.2021.584955
van Nunen E, Hoek G, Tsai M.Y, Probst-Hensch N, Imboden M, Jeong A, Naccarati A, Tarallo S, Raffaele D, Nieuwenhuijsen M, Vlaanderen J, Gulliver J, Amaral A.F.S, Vineis P, Vermeulen R. Short-term personal and outdoor exposure to ultrafine and fine particulate air pollution in association with blood pressure and lung function in healthy adults. Environ Res. 2021;194:110579. DOI: 10.1016/j.envres.2020.110579
Accordini S, Calciano L, Marcon A, Pesce G, Anto J.M, Beckmeyer-Borowko A.B, Carsin A.E, Corsico A.G, Imboden M, Janson C, Keidel D, Locatelli F, Svanes C, Burney P.G.J, Jarvis D, Probst-Hensch N.M, Minelli C. Incidence trends of airflow obstruction among European adults without asthma: a 20-year cohort study. Sci Rep. 2020;10:3452. DOI: 10.1038/s41598-020-60478-5
Aebi N.J, Bringolf-Isler B, Schaffner E, Caviezel S, Imboden M, Probst-Hensch N. Patterns of cross-sectional and predictive physical activity in Swiss adults aged 52+: results from the SAPALDIA cohort. Swiss Med Wkly. 2020;150:w20266. DOI: 10.4414/smw.2020.20266
Amaral A.F.S, Imboden M, Wielscher M, Rezwan F.I, Minelli C, Garcia-Aymerich J, Peralta G.P, Auvinen J, Jeong A, Schaffner E, Beckmeyer-Borowko A, Holloway J.W, Jarvelin M.R, Probst-Hensch N.M, Jarvis D.L, ALEC consortium. Role of DNA methylation in the association of lung function with body mass index: a two-step epigenetic Mendelian randomisation study. BMC Pulm Med. 2020;20:171. DOI: 10.1186/s12890-020-01212-9
Carsin A.E, Keidel D, Fuertes E, Imboden M, Weyler J, Nowak D, Heinrich J, Pascual Erquicia S, Martinez-Moratalla J, Huerta I, Sanchez J.L, Schaffner E, Caviezel S, Beckmeyer-Borowko A, Raherison C, Pin I, Demoly P, Leynaert B, Cerveri I, Squillacioti G, Accordini S, Gislason T, Svanes C, Toren K, Forsberg B, Janson C, Jogi R, Emtner M, Gomez Real F, Jarvis D, Guerra S, Dharmage S.C, Probst-Hensch N, Garcia-Aymerich J. Regular physical activity levels and incidence of restrictive spirometry pattern: a longitudinal analysis of two population-based cohorts. Am J Epidemiol. 2020;89(12):1521-1528. DOI: 10.1093/aje/kwaa087
Cerletti P, Eze I.C, Schaffner E, Foraster M, Vienneau D, Cajochen C, Wunderli J.M, Röösli M, Stolz D, Pons M, Imboden M, Probst-Hensch N. The independent association of source-specific transportation noise exposure, noise annoyance and noise sensitivity with health-related quality of life. Environ Int. 2020;143:105960. DOI: 10.1016/j.envint.2020.105960
Cerletti P, Keidel D, Imboden M, Schindler C, Probst-Hensch N. The modifying role of physical activity in the cross-sectional and longitudinal association of health-related quality of life with physiological functioning-based latent classes and metabolic syndrome. Health Qual Life Outcomes. 2020;18:345. DOI: 10.1186/s12955-020-01557-z
Demetz E, Tymoszuk P, Hilbe R, Volani C, Haschka D, Heim C, Auer K, Lener D, Zeiger L.B, Pfeifhofer-Obermair C, Boehm A, Obermair G.J, Ablinger C, Coassin S, Lamina C, Kager J, Petzer V, Asshoff M, Schroll A, Nairz M, Dichtl S, Seifert M, von Raffay L, Fischer C, Barros-Pinkelnig M, Brigo N, Valente de Souza L, Sopper S, Hirsch J, Graber M, Gollmann-Tepekoylu C, Holfeld J, Halper J, Macheiner S, Gostner J, Vogel G.F, Pechlaner R, Moser P, Imboden M, Marques-Vidal P, Probst-Hensch N.M, Meiselbach H, Strauch K, Peters A, Paulweber B, Willeit J, Kiechl S, Kronenberg F, Theurl I, Tancevski I, Weiss G. The haemochromatosis gene Hfe and Kupffer cells control LDL cholesterol homeostasis and impact on atherosclerosis development. Eur Heart J. 2020;41(40):3949-3959. DOI: 10.1093/eurheartj/ehaa140
Eze I.C, Foraster M, Schaffner E, Vienneau D, Pieren R, Imboden M, Wunderli J.M, Cajochen C, Brink M, Röösli M, Probst-Hensch N. Incidence of depression in relation to transportation noise exposure and noise annoyance in the SAPALDIA study. Environ Int. 2020;144:106014. DOI: 10.1016/j.envint.2020.106014
Eze I.C, Jeong A, Schaffner E, Rezwan F.I, Ghantous A, Foraster M, Vienneau D, Kronenberg F, Herceg Z, Vineis P, Brink M, Wunderli J.M, Schindler C, Cajochen C, Röösli M, Holloway J.W, Imboden M, Probst-Hensch N. Genome-wide DNA methylation in peripheral blood and long-term exposure to source-specific transportation noise and air pollution: the SAPALDIA study. Environ Health Perspect. 2020;128(6):67003. DOI: 10.1289/EHP6174
Fawcett K.A, Obeidat M, Melbourne C, Shrine N, Guyatt A.L, John C, Luan J, Richmond A, Moksnes M.R, Granell R, Weiss S, Imboden M, May-Wilson S, Hysi P, Boutin T.S, Portas L, Flexeder C, Harris S.E, Wang C.A, Lyytikainen L.P, Palviainen T, Foong R.E, Keidel D, Minelli C, Langenberg C, Bosse Y, Van den Berge M, Sin D.D, Hao K, Campbell A, Porteous D, Padmanabhan S, Smith B.H, Evans D.M, Ring S, Langhammer A, Hveem K, Willer C, Ewert R, Stubbe B, Pirastu N, Klaric L, Joshi P.K, Patasova K, Massimo M, Polasek O, Starr J.M, Karrasch S, Strauch K, Meitinger T, Rudan I, Rantanen T, Pietilainen K, Kahonen M, Raitakari O.T, Hall G.L, Sly P.D, Pennell C.E, Kaprio J, Lehtimaki T, Vitart V, Deary I.J, Jarvis D, Wilson J.F, Spector T, Probst-Hensch N, Wareham N.J, Volzke H, Henderson J, Strachan D.P, Brumpton B.M, Hayward C, Hall I.P, Tobin M.D, Wain L.V. Variants associated with HHIP expression have sex-differential effects on lung function. Wellcome Open Res. 2020;5:111. DOI: 10.12688/wellcomeopenres.15846.1
Hoang T.T, Sikdar S, Xu C.J, Lee M.K, Cardwell J, Forno E, Imboden M, Jeong A, Madore A.M, Qi C, Wang T, Bennett B.D, Ward J.M, Parks C.G, Beane-Freeman L.E, King D, Motsinger-Reif A, Umbach D.M, Wyss A.B, Schwartz D.A, Celedon J.C, Laprise C, Ober C, Probst-Hensch N, Yang I.V, Koppelman G.H, London S.J. Epigenome-wide association study of DNA methylation and adult asthma in the agricultural lung health study. Eur Respir J. 2020;56(3):2000217. DOI: 10.1183/13993003.00217-2020
Mancini F.R, Laine J.E, Tarallo S, Vlaanderen J, Vermeulen R, van Nunen E, Hoek G, Probst-Hensch N, Imboden M, Jeong A, Gulliver J, Chadeau-Hyam M, Nieuwenhuijsen M, de Kok T.M, Piepers J, Krauskopf J, Kleinjans J.C.S, Vineis P, Naccarati A. microRNA expression profiles and personal monitoring of exposure to particulate matter. Environ Pollut. 2020;263(Pt B):114392. DOI: 10.1016/j.envpol.2020.114392
Rezwan F.I, Imboden M, Amaral A.F.S, Wielscher M, Jeong A, Triebner K, Real F.G, Jarvelin M.R, Jarvis D, Probst-Hensch N.M, Holloway J.W. Association of adult lung function with accelerated biological aging. Aging. 2020;12(1):518-542. DOI: 10.18632/aging.102639
Schmidt J.C, Vogt S, Imboden M, Schaffner E, Grize L, Zemp E, Probst-Hensch N, Zitzmann N.U. Dental and periodontal health in a Swiss population-based sample of older adults: a cross-sectional study. Eur J Oral Sci. 2020;128:508-517. DOI: 10.1111/eos.12738
van Nunen E, Vermeulen R, Tsai M.Y, Probst-Hensch N, Ineichen A, Imboden M, Naccarati A, Tarallo S, Raffaele D, Ranzi A, Nieuwenhuijsen M, Jarvis D, Amaral A.F, Vlaanderen J, Meliefste K, Brunekreef B, Vineis P, Gulliver J, Hoek G. Associations between modeled residential outdoor and measured personal exposure to ultrafine particles in four European study areas. Atmos Environ. 2020;226:117353. DOI: 10.1016/j.atmosenv.2020.117353
Journal Article
West E.A, Anker D, Amati R, Richard A, Wisniak A, Butty A, Albanese E, Bochud M, Chiolero A, Crivelli L, Cullati S, d'Acremont V, Epure A.M, Fehr J, Flahault A, Fornerod L, Frank I, Frei A, Michel G, Gonseth S, Guessous I, Imboden M, Kahlert C.R, Kaufmann L, Kohler P, Mösli N, Paris D, Probst-Hensch N, Rodondi N, Stringhini S, Vermes T, Vollrath F, Puhan M.A, Corona Immunitas Research Group. Corona immunitas: study protocol of a nationwide program of SARS-CoV-2 seroprevalence and seroepidemiologic studies in Switzerland. Int J Public Health. 2020;65:1529–1548. DOI: 10.1007/s00038-020-01494-0
Carsin A.E, Fuertes E, Schaffner E, Jarvis D, Antó J.M, Heinrich J, Bellisario V, Svanes C, Keidel D, Imboden M, Weyler J, Nowak D, Martinez-Moratalla J, Gullón J.A, Sanchez Ramos J.L, Caviezel S, Beckmeyer-Borowko A, Raherison C, Pin I, Demoly P, Cerveri I, Accordini S, Gislason T, Toren K, Forsberg B, Janson C, Jogi R, Emtner M, Gómez Real F, Raza W, Leynaert B, Pascual S, Guerra S, Dharmage S.C, Probst-Hensch N, Garcia-Aymerich J. Restrictive spirometry pattern is associated with low physical activity levels. A population based international study. Respir Med. 2019;146:116-123. DOI: 10.1016/j.rmed.2018.11.017
Eze I.C, Essé C, Bassa F.K, Koné S, Acka F, Schindler C, Imboden M, Laubhouet-Koffi V, Kouassi D, N'Goran E.K, Utzinger J, Bonfoh B, Probst-Hensch N. Asymptomatic Plasmodium infection and glycemic control in adults: results from a population-based survey in south-central Côte d'Ivoire. Diabetes Res Clin Pract. 2019;156:107845. DOI: 10.1016/j.diabres.2019.107845
Imboden M, Wielscher M, Rezwan F.I, Amaral A.F.S, Schaffner E, Jeong A, Beckmeyer-Borowko A, Harris S.E, Starr J.M, Deary I.J, Flexeder C, Waldenberger M, Peters A, Schulz H, Chen S, Sunny S.K, Karmaus W.J.J, Jiang Y, Erhart G, Kronenberg F, Arathimos R, Sharp G.C, Henderson A.J, Fu Y, Piirilä P, Pietiläinen K.H, Ollikainen M, Johansson A, Gyllensten U, de Vries M, van der Plaat D.A, de Jong K, Boezen H.M, Hall I.P, Tobin M.D, Jarvelin M.R, Holloway J.W, Jarvis D, Probst-Hensch N.M. Epigenome-wide association study of lung function level and its change. Eur Respir J. 2019;54:1900457. DOI: 10.1183/13993003.00457-2019
Jeong A, Imboden M, Ghantous A, Novoloaca A, Carsin A.E, Kogevinas M, Schindler C, Lovison G, Herceg Z, Cuenin C, Vermeulen R, Jarvis D, Amaral A.F.S, Kronenberg F, Vineis P, Probst-Hensch N. DNA methylation in inflammatory pathways modifies the association between BMI and adult-onset non-atopic asthma. Int J Environ Res Public Health. 2019;16(4):600. DOI: 10.3390/ijerph16040600
Meier-Girard D, Delgado-Eckert E, Schaffner E, Schindler C, Künzli N, Adam M, Pichot V, Kronenberg F, Imboden M, Frey U, Probst-Hensch N. Association of long-term exposure to traffic-related PM10 with heart rate variability and heart rate dynamics in healthy subjects. Environ Int. 2019;125:107-116. DOI: 10.1016/j.envint.2019.01.031
Mostafavi N, Jeong A, Vlaanderen J, Imboden M, Vineis P, Jarvis D, Kogevinas M, Probst-Hensch N, Vermeulen R. The mediating effect of immune markers on the association between ambient air pollution and adult-onset asthma. Sci Rep. 2019;9:8818. DOI: 10.1038/s41598-019-45327-4
Sakornsakolpat P, Prokopenko D, Lamontagne M, Reeve N.F, Guyatt A.L, Jackson V.E, Shrine N, Qiao D, Bartz T.M, Kim D.K, Lee M.K, Latourelle J.C, Li X, Morrow J.D, Obeidat M, Wyss A.B, Bakke P, Barr R.G, Beaty T.H, Belinsky S.A, Brusselle G.G, Crapo J.D, de Jong K, DeMeo D.L, Fingerlin T.E, Gharib S.A, Gulsvik A, Hall I.P, Hokanson J.E, Kim W.J, Lomas D.A, London S.J, Meyers D.A, O'Connor G.T, Rennard S.I, Schwartz D.A, Sliwinski P, Sparrow D, Strachan D.P, Tal-Singer R, Tesfaigzi Y, Vestbo J, Vonk J.M, Yim J.J, Zhou X, Bosse Y, Manichaikul A, Lahousse L, Silverman E.K, Boezen H.M, Wain L.V, Tobin M.D, Hobbs B.D, Cho M.H, SpiroMeta Consortium, International COPD Genetics Consortium. Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations. Nat Genet. 2019;51(3):494-505. DOI: 10.1038/s41588-018-0342-2
Shrine N, Guyatt A.L, Erzurumluoglu A.M, Jackson V.E, Hobbs B.D, Melbourne C.A, Batini C, Fawcett K.A, Song K, Sakornsakolpat P, Li X, Boxall R, Reeve N.F, Obeidat M, Zhao J.H, Wielscher M, Understanding Society Scientific Group, Weiss S, Kentistou K.A, Cook J.P, Sun B.B, Zhou J, Hui J, Karrasch S, Imboden M, Harris S.E, Marten J, Enroth S, Kerr S.M, Surakka I, Vitart V, Lehtimaki T, Allen R.J, Bakke P.S, Beaty T.H, Bleecker E.R, Bosse Y, Brandsma C.A, Chen Z, Crapo J.D, Danesh J, DeMeo D.L, Dudbridge F, Ewert R, Gieger C, Gulsvik A, Hansell A.L, Hao K, Hoffman J.D, Hokanson J.E, Homuth G, Joshi P.K, Joubert P, Langenberg C, Li X, Li L, Lin K, Lind L, Locantore N, Luan J, Mahajan A, Maranville J.C, Murray A, Nickle D.C, Packer R, Parker M.M, Paynton M.L, Porteous D.J, Prokopenko D, Qiao D, Rawal R, Runz H, Sayers I, Sin D.D, Smith B.H, Artigas M.S, Sparrow D, Tal-Singer R, Timmers Prhj, Van den Berge M, Whittaker J.C, Woodruff P.G, Yerges-Armstrong L.M, Troyanskaya O.G, Raitakari O.T, Kahonen M, Polasek O, Gyllensten U, Rudan I, Deary I.J, Probst-Hensch N.M, Schulz H, James A.L, Wilson J.F, Stubbe B, Zeggini E, Jarvelin M.R, Wareham N, Silverman E.K, Hayward C, Morris A.P, Butterworth A.S, Scott R.A, Walters R.G, Meyers D.A, Cho M.H, Strachan D.P, Hall I.P, Tobin M.D, Wain L.V. Author correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. Nat Genet. 2019;51:1067-1068. DOI: 10.1038/s41588-019-0438-3
Shrine N, Guyatt A.L, Erzurumluoglu A.M, Jackson V.E, Hobbs B.D, Melbourne C.A, Batini C, Fawcett K.A, Song K, Sakornsakolpat P, Li X, Boxall R, Reeve N.F, Obeidat M, Zhao J.H, Wielscher M, Understanding Society Scientific Group, Weiss S, Kentistou K.A, Cook J.P, Sun B.B, Zhou J, Hui J, Karrasch S, Imboden M, Harris S.E, Marten J, Enroth S, Kerr S.M, Surakka I, Vitart V, Lehtimäki T, Allen R.J, Bakke P.S, Beaty T.H, Bleecker E.R, Bossé Y, Brandsma C.A, Chen Z, Crapo J.D, Danesh J, DeMeo D.L, Dudbridge F, Ewert R, Gieger C, Gulsvik A, Hansell A.L, Hao K, Hoffman J.D, Hokanson J.E, Homuth G, Joshi P.K, Joubert P, Langenberg C, Li X, Li L, Lin K, Lind L, Locantore N, Luan J, Mahajan A, Maranville J.C, Murray A, Nickle D.C, Packer R, Parker M.M, Paynton M.L, Porteous D.J, Prokopenko D, Qiao D, Rawal R, Runz H, Sayers I, Sin D.D, Smith B.H, Soler Artigas M, Sparrow D, Tal-Singer R, Timmers Prhj, Van den Berge M, Whittaker J.C, Woodruff P.G, Yerges-Armstrong L.M, Troyanskaya O.G, Raitakari O.T, Kähönen M, Polašek O, Gyllensten U, Rudan I, Deary I.J, Probst-Hensch N.M, Schulz H, James A.L, Wilson J.F, Stubbe B, Zeggini E, Jarvelin M.R, Wareham N, Silverman E.K, Hayward C, Morris A.P, Butterworth A.S, Scott R.A, Walters R.G, Meyers D.A, Cho M.H, Strachan D.P, Hall I.P, Tobin M.D, Wain L.V. New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. Nat Genet. 2019;51(3):481-493. DOI: 10.1038/s41588-018-0321-7
Accordini S, Calciano L, Marcon A, Pesce G, Anto J, Beckmeyer-Borowko A, Corsico A, Imboden M, Janson C, Keidel D, Locatelli F, Svanes C, Jarvis D, Probst-Hensch N, Minelli C. Incidence of airflow obstruction over 20 years in Europe. Eur Respir J, 2018;52(Suppl. 62):PA2267. DOI: 10.1183/13993003.congress-2018.PA2267
Conference Paper
Amaral A.F.S, Imboden M, Wielscher M, Rezwan F.I, Minelli C, Garcia-Aymerich J, Peralta G.P, Auvinen J, Jeong A, Schaffner E, Beckmeyer-Borowko A, Holloway J.W, Jarvelin M.R, Probst-Hensch N, Jarvis D.L. Body mass index and lung function: a two-step epigenetic Mendelian randomization study. Eur Respir J, 2018;52(Suppl. 62):PA1276. DOI: 10.1183/13993003.congress-2018.PA1276
Conference Paper
Beckmeyer-Borowko A, Imboden M, Rezwan F.I, Wielscher M, Amaral A.F.S, Jeong A, Schaffner E, Auvinen J, Sebert S, Karhunen V, Bettschart R, Turk A, Pons M, Stolz D, Kronenberg F, Arathimos R, Sharp G.C, Relton C, Henderson A.J, Jarvelin M.R, Jarvis D, Holloway J.W, Probst-Hensch N.M. SERPINA1 methylation and lung function in tobacco-smoke exposed European children and adults: a meta-analysis of ALEC population-based cohorts. Respir Res. 2018;19(1):156. DOI: 10.1186/s12931-018-0850-8
Carsin A.E, Keidel D, Fuertes E, Imboden M, Weyler J, Nowak D, Heinrich J, Urrutia I, Martinez-Moratalla J, Caviezel S, Beckmeyer-Borowko A, Raherison C, Pin I, Demoly P, Leynaert B, Cerveri I, Bono R, Accordini S, Amaral A, Gislason T, Svanes C, Toren K, Forsberg B, Janson C, Dharmage S, Jogi R, Anto J, Probst-Hensch N, Garcia-Aymerich J. Physical activity and incidence of restrictive spirometry pattern in adults. Eur Respir J, 2018;52(Suppl. 62):PA5289. DOI: 10.1183/13993003.congress-2018.PA5289
Conference Paper
Curjuric I, Imboden M, Bettschart R, Caviezel S, Dratva J, Pons M, Rothe T, Schmidt-Trucksäss A, Stolz D, Thun G.A, Eckardstein A.V, Kronenberg F, Ferrarotti I, Probst-Hensch N.M. Alpha-1 antitrypsin deficiency: from the lung to the heart?. Atherosclerosis. 2018;270:166-172. DOI: 10.1016/j.atherosclerosis.2018.01.042
Demenais F, Margaritte-Jeannin P, Barnes K.C, Cookson W.O.C, Altmuller J, Ang W, Barr R.G, Beaty T.H, Becker A.B, Beilby J, Bisgaard H, Bjornsdottir U.S, Bleecker E, Bonnelykke K, Boomsma D.I, Bouzigon E, Brightling C.E, Brossard M, Brusselle G.G, Burchard E, Burkart K.M, Bush A, Chan-Yeung M, Chung K.F, Couto Alves A, Curtin J.A, Custovic A, Daley D, de Jongste J.C, Del-Rio-Navarro B.E, Donohue K.M, Duijts L, Eng C, Eriksson J.G, Farrall M, Fedorova Y, Feenstra B, Ferreira M.A, Freidin M.B, Gajdos Z, Gauderman J, Gehring U, Geller F, Genuneit J, Gharib S.A, Gilliland F, Granell R, Graves P.E, Gudbjartsson D.F, Haahtela T, Heckbert S.R, Heederik D, Heinrich J, Heliovaara M, Henderson J, Himes B.E, Hirose H, Hirschhorn J.N, Hofman A, Holt P, Hottenga J, Hudson T.J, Hui J, Imboden M, Ivanov V, Jaddoe V.W.V, James A, Janson C, Jarvelin M.R, Jarvis D, Jones G, Jonsdottir I, Jousilahti P, Kabesch M, Kahonen M, Kantor D.B, Karunas A.S, Khusnutdinova E, Koppelman G.H, Kozyrskyj A.L, Kreiner E, Kubo M, Kumar R, Kumar A, Kuokkanen M, Lahousse L, Laitinen T, Laprise C, Lathrop M, Lau S, Lee Y.A, Lehtimaki T, Letort S, Levin A.M, Li G, Liang L, Loehr L.R, London S.J, Loth D.W, Manichaikul A, Marenholz I, Martinez F.J, Matheson M.C, Mathias R.A, Matsumoto K, Mbarek H, McArdle W.L, Melbye M, Melen E, Meyers D, Michel S, Mohamdi H, Musk A.W, Myers R.A, Nieuwenhuis M.A.E, Noguchi E, O'Connor G.T, Ogorodova L.M, Palmer C.D, Palotie A, Park J.E, Pennell C.E, Pershagen G, Polonikov A, Postma D.S, Probst-Hensch N, Puzyrev V.P, Raby B.A, Raitakari O.T, Ramasamy A, Rich S.S, Robertson C.F, Romieu I, Salam M.T, Salomaa V, Schlunssen V, Scott R, Selivanova P.A, Sigsgaard T, Simpson A, Siroux V, Smith L.J, Solodilova M, Standl M, Stefansson K, Strachan D.P, Stricker B.H, Takahashi A, Thompson P.J, Thorleifsson G, Thorsteinsdottir U, Tiesler C.M.T, Torgerson D.G, Tsunoda T, Uitterlinden A.G, Van der Valk R.J.P, Vaysse A, Vedantam S, Von Berg A, Von Mutius E, Vonk J.M, Waage J, Wareham N.J, Weiss S.T, White W.B, Wickman M, Widen E, Willemsen G, Williams L.K, Wouters I.M, Yang J.J, Zhao J.H, Moffatt M.F, Ober C, Nicolae D.L, Australian Asthma Genetics Consortium Collaborators. Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. Nat Genet. 2018;50:42-53. (AAGC). DOI: 10.1038/s41588-017-0014-7
Gulliver J, Morley D, Dunster C, McCrea A, Van Nunen E, Tsai M, Probst-Hensch N, Eeftens M, Imboden M, Ducret-Stich R, Naccarati A, Cirachi M, Vermeulen, Vineis P, Hoek G, Kelly F.J. Land use regression models for the oxidative potential of fine particles (PM2.5) in five European areas. Environ Res. 2018;160:247-255. DOI: 10.1016/j.envres.2017.10.002
Htun N.S.N, Odermatt P, Paboriboune P, Sayasone S, Vongsakid M, Phimolsarn-Nusith V, Tran X.D, Ounnavong P.S, Andriama-Hefasoa N, Senvanpan N.D, Homsana A, Lianosay B, Xayavong D, Robinson D.R, Bounsavath P, Prasayasith P.P, Syphan S.D, Lu Y.X, Thilakoun K, Xaiyaphet X.S, Vongngakesone P.T, Eze I.C, Imboden M, Sripa B, Reinharz D, Probst-Hensch N. Association between helminth infections and diabetes mellitus in adults from the Lao People's Democratic Republic: a cross-sectional study. Infect Dis Poverty. 2018;7:105. DOI: 10.1186/s40249-018-0488-2
Jackson V.E, Latourelle J.C, Wain L.V, Smith A.V, Grove M.L, Bartz T.M, Obeidat M, Province M.A, Gao W, Qaiser B, Porteous D.J, Cassano P.A, Ahluwalia T.S, Grarup N, Li J, Altmaier E, Marten J, Harris S.E, Manichaikul A, Pottinger T.D, Li-Gao R, Lind-Thomsen A, Mahajan A, Lahousse L, Imboden M, Teumer A, Prins B, Lyytikainen L.P, Eiriksdottir G, Franceschini N, Sitlani C.M, Brody J.A, Bosse Y, Timens W, Kraja A, Loukola A, Tang W, Liu Y, Bork-Jensen J, Justesen J.M, Linneberg A, Lange L.A, Rawal R, Karrasch S, Huffman J.E, Smith B.H, Davies G, Burkart K.M, Mychaleckyj J.C, Bonten T.N, Enroth S, Lind L, Brusselle G.G, Kumar A, Stubbe B, Understanding Society Scientific Group, Kahonen M, Wyss A.B, Psaty B.M, Heckbert S.R, Hao K, Rantanen T, Kritchevsky S.B, Lohman K, Skaaby T, Pisinger C, Hansen T, Schulz H, Polasek O, Campbell A, Starr J.M, Rich S.S, Mook-Kanamori D.O, Johansson A, Ingelsson E, Uitterlinden A.G, Weiss S, Raitakari O.T, Gudnason V, North K.E, Gharib S.A, Sin D.D, Taylor K.D, O'Connor G.T, Kaprio J, Harris T.B, Pederson O, Vestergaard H, Wilson J.G, Strauch K, Hayward C, Kerr S, Deary I.J, Barr R.G, de Mutsert R, Gyllensten U, Morris A.P, Ikram M.A, Probst-Hensch N, Glaser S, Zeggini E, Lehtimaki T, Strachan D.P, Dupuis J, Morrison A.C, Hall I.P, Tobin M.D, London S.J. Meta-analysis of exome array data identifies six novel genetic loci for lung function. Wellcome Open Res. 2018;3:4. DOI: 10.12688/wellcomeopenres.12583.3
Jeong A, Fiorito G, Keski-Rahkonen P, Imboden M, Kiss A, Robinot N, Gmuender H, Vlaandere J, Vermeulen R, Kyrtopoulos S, Herceg Z, Ghantous A, Lovison G, Galassi C, Ranzi A, Krogh V, Grioni S, Agnoli C, Sacerdote C, Mostafavi N, Naccarati A, Scalbert A, Vineis P, Probst-Hensch N, EXPOsOMICS Consortium. Perturbation of metabolic pathways mediates the association of air pollutants with asthma and cardiovascular diseases. Environ Int. 2018;119:334-345. DOI: 10.1016/j.envint.2018.06.025
Marcon A, Locatelli F, Keidel D, Beckmeyer-Borowko A.B, Cerveri I, Dharmage S.C, Fuertes E, Garcia-Aymerich J, Heinrich J, Imboden M, Janson C, Johannessen A, Leynaert B, Pascual Erquicia S, Pesce G, Schaffner E, Svanes C, Urrutia I, Jarvis D, Probst-Hensch N.M, Accordini S, Ageing Lungs in European Cohorts study. Airway responsiveness to methacholine and incidence of COPD: an international prospective cohort study. Thorax. 2018;73(9):825-832. DOI: 10.1136/thoraxjnl-2017-211289
Mostafavi N, Vermeulen R, Ghantous A, Hoek G, Probst-Hensch N, Herceg Z, Tarallo S, Naccarati A, Kleinjans J.C.S, Imboden M, Jeong A, Morley D, Amaral A.F.S, Van Nunen E, Gulliver J, Chadeau-Hyam M, Vineis P, Vlaanderen J. Acute changes in DNA methylation in relation to 24 h personal air pollution exposure measurements: a panel study in four European countries. Environ Int. 2018;120:11-21. DOI: 10.1016/j.envint.2018.07.026
Vonk J.M, Nieuwenhuis M.A.E, Dijk F.N, Boudier A, Siroux V, Bouzigon E, Probst-Hensch N, Imboden M, Keidel D, Sin D, Bossé Y, Hao K, van den Berge M, Faiz A, Koppelman G.H, Postma D.S. Novel genes and insights in complete asthma remission: a genome-wide association study on clinical and complete asthma remission. Clin Exp Allergy. 2018;48(10):1286-1296. DOI: 10.1111/cea.13181
Waage J, Standl M, Curtin J.A, Jessen L.E, Thorsen J, Tian C, Schoettler N, Me Research Team, AAGC collaborators, Flores C, Abdellaoui A, Ahluwalia T.S, Alves A.C, Amaral A.F.S, Anto J.M, Arnold A, Barreto-Luis A, Baurecht H, van Beijsterveldt C.E.M, Bleecker E.R, Bonas-Guarch S, Boomsma D.I, Brix S, Bunyavanich S, Burchard E.G, Chen Z, Curjuric I, Custovic A, den Dekker H.T, Dharmage S.C, Dmitrieva J, Duijts L, Ege M.J, Gauderman W.J, Georges M, Gieger C, Gilliland F, Granell R, Gui H, Hansen T, Heinrich J, Henderson J, Hernandez-Pacheco N, Holt P, Imboden M, Jaddoe V.W.V, Jarvelin M.R, Jarvis D.L, Jensen K.K, Jonsdottir I, Kabesch M, Kaprio J, Kumar A, Lee Y.A, Levin A.M, Li X, Lorenzo-Diaz F, Melen E, Mercader J.M, Meyers D.A, Myers R, Nicolae D.L, Nohr E.A, Palviainen T, Paternoster L, Pennell C.E, Pershagen G, Pino-Yanes M, Probst-Hensch N.M, Ruschendorf F, Simpson A, Stefansson K, Sunyer J, Sveinbjornsson G, Thiering E, Thompson P.J, Torrent M, Torrents D, Tung J.Y, Wang C.A, Weidinger S, Weiss S, Willemsen G, Williams L.K, Ober C, Hinds D.A, Ferreira M.A, Bisgaard H, Strachan D.P, Bonnelykke K. Author correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis (Nature Genetics, (2018), 50, 8, (1072-1080), 10.1038/s41588-018-0157-1). Nat Genet. 2018;50(9):1343. DOI: 10.1038/s41588-018-0197-6
Journal Item
Adam M, Imboden M, Schaffner E, Boes E, Kronenberg F, Pons M, Bettschart R, Barthelemy J.C, Schindler C, Probst-Hensch N. The adverse impact of obesity on heart rate variability is modified by a NFE2L2 gene variant: the SAPALDIA Cohort. Int J Cardiol. 2017;228:341-346. DOI: 10.1016/j.ijcard.2016.11.049
De Jong K, Vonk J.M, Imboden M, Lahousse L, Hofman A, Brusselle G.G, Probst-Hensch N.M, Postma D.S, Boezen H.M. Genes and pathways underlying susceptibility to impaired lung function in the context of environmental tobacco smoke exposure. Respir Res. 2017;18:142. DOI: 10.1186/s12931-017-0625-7
Eze I.C, Esse C, Bassa F.K, Koné S, Acka F, Yao L, Imboden M, Jaeger F.N, Schindler C, Dosso M, Laubhouet-Koffi V, Kouassi D, N'Goran E.K, Utzinger J, Bonfoh B, Probst-Hensch N. Côte d'Ivoire Dual Burden of Disease (CoDuBu): study protocol to investigate the co-occurrence of chronic infections and noncommunicable diseases in rural settings of epidemiological transition. JMIR Res Protoc. 2017;6(10):e210. DOI: 10.2196/resprot.8599
Eze I.C, Foraster M, Schaffner E, Vienneau D, Héritier H, Rudzik F, Thiesse L, Pieren R, Imboden M, von Eckardstein A, Schindler C, Brink M, Cajochen C, Wunderli J.M, Röösli M, Probst-Hensch N. Long-term exposure to transportation noise and air pollution in relation to incident diabetes in the SAPALDIA study. Int J Epidemiol. 2017;46(4):1115-1125. DOI: 10.1093/ije/dyx020
Eze I.C, Imboden M, Foraster M, Schaffner E, Kumar A, Vienneau D, Héritier H, Rudzik F, Thiesse L, Pieren R, von Eckardstein A, Schindler C, Brink M, Wunderli J.M, Cajochen C, Röösli M, Probst-Hensch N. Exposure to night-time traffic noise, melatonin-regulating gene variants and change in glycemia in adults. Int J Environ Res Public Health. 2017;14(12):E1492. DOI: 10.3390/ijerph14121492
Gorski M, van der Most P.J, Teumer A, Chu A.Y, Li M, Mijatovic V, Nolte I.M, Cocca M, Taliun D, Gomez F, Li Y, Tayo B, Tin A, Feitosa M.F, Aspelund T, Attia J, Biffar R, Bochud M, Boerwinkle E, Borecki I, Bottinger E.P, Chen M.H, Chouraki V, Ciullo M, Coresh J, Cornelis M.C, Curhan G.C, Adamo A.P, Dehghan A, Dengler L, Ding J, Eiriksdottir G, Endlich K, Enroth S, Esko T, Franco O.H, Gasparini P, Gieger C, Girotto G, Gottesman O, Gudnason V, Gyllensten U, Hancock S.J, Harris T.B, Helmer C, Hollerer S, Hofer E, Hofman A, Holliday E.G, Homuth G, Hu F.B, Huth C, Hutri-Kahonen N, Hwang S.J, Imboden M, Johansson A, Kahonen M, Konig W, Kramer H, Kramer B.K, Kumar A, Kutalik Z, Lambert J.C, Launer L.J, Lehtimaki T, Borst M.H, Navis G, Swertz M, Liu Y, Lohman K, Loos R.J.F, Lu Y, Lyytikainen L.P, McEvoy M.A, Meisinger C, Meitinger T, Metspalu A, Metzger M, Mihailov E, Mitchell P, Nauck M, Oldehinkel A.J, Olden M, Wjh Penninx B, Pistis G, Pramstaller P.P, Probst-Hensch N, Raitakari O.T, Rettig R, Ridker P.M, Rivadeneira F, Robino A, Rosas S.E, Ruderfer D, Ruggiero D, Saba Y, Sala C, Schmidt H, Schmid R, Scott R.J, Sedaghat S, Smith A.V, Sorice R, Stengel B, Stracke S, Strauch K, Toniolo D, Uitterlinden A.G, Ulivi S, Viikari J.S, Volker U, Vollenweider P, Volzke H, Vuckovic D, Waldenberger M, Wang J.J, Yang Q, Chasman D.I, Tromp G, Snieder H, Heid I.M, Fox C.S, Kottgen A, Pattaro C, Boger C.A, Fuchsberger C. Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function. Sci Rep. 2017;7:46835. DOI: 10.1038/srep46835
Gorski M, van der Most P.J, Teumer A, Chu A.Y, Li M, Mijatovic V, Nolte I.M, Cocca M, Taliun D, Gomez F, Li Y, Tayo B, Tin A, Feitosa M.F, Aspelund T, Attia J, Biffar R, Bochud M, Boerwinkle E, Borecki I, Bottinger E.P, Chen M.H, Chouraki V, Ciullo M, Coresh J, Cornelis M.C, Curhan G.C, d'Adamo A.P, Dehghan A, Dengler L, Ding J, Eiriksdottir G, Endlich K, Enroth S, Esko T, Franco O.H, Gasparini P, Gieger C, Girotto G, Gottesman O, Gudnason V, Gyllensten U, Hancock S.J, Harris T.B, Helmer C, Hollerer S, Hofer E, Hofman A, Holliday E.G, Homuth G, Hu F.B, Huth C, Hutri-Kahonen N, Hwang S.J, Imboden M, Johansson A, Kahonen M, Konig W, Kramer H, Kramer B.K, Kumar A, Kutalik Z, Lambert J.C, Launer L.J, Lehtimaki T, de Borst M, Navis G, Swertz M, Liu Y, Lohman K, Loos R.J.F, Lu Y, Lyytikainen L.P, McEvoy M.A, Meisinger C, Meitinger T, Metspalu A, Metzger M, Mihailov E, Mitchell P, Nauck M, Oldehinkel A.J, Olden M, Wjh Penninx B, Pistis G, Pramstaller P.P, Probst-Hensch N, Raitakari O.T, Rettig R, Ridker P.M, Rivadeneira F, Robino A, Rosas S.E, Ruderfer D, Ruggiero D, Saba Y, Sala C, Schmidt H, Schmid R, Scott R.J, Sedaghat S, Smith A.V, Sorice R, Stengel B, Stracke S, Strauch K, Toniolo D, Uitterlinden A.G, Ulivi S, Viikari J.S, Volker U, Vollenweider P, Volzke H, Vuckovic D, Waldenberger M, Jin Wang J, Yang Q, Chasman D.I, Tromp G, Snieder H, Heid I.M, Fox C.S, Kottgen A, Pattaro C, Boger C.A, Fuchsberger C. 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function. Sci Rep. 2017;7:45040. DOI: 10.1038/srep45040
Jeong A, Imboden M, Hansen S, Zemp E, Bridevaux P.O, Lovison G, Schindler C, Probst-Hensch N. Heterogeneity of obesity-asthma association disentangled by latent class analysis, the SAPALDIA cohort. Respir Med. 2017;125:25-32. DOI: 10.1016/j.rmed.2017.02.014
Li M, Li Y, Weeks O, Mijatovic V, Teumer A, Huffman J.E, Tromp G, Fuchsberger C, Gorski M, Lyytikainen L.P, Nutile T, Sedaghat S, Sorice R, Tin A, Yang Q, Ahluwalia T.S, Arking D.E, Bihlmeyer N.A, Boger C.A, Carroll R.J, Chasman D.I, Cornelis M.C, Dehghan A, Faul J.D, Feitosa M.F, Gambaro G, Gasparini P, Giulianini F, Heid I, Huang J, Imboden M, Jackson A.U, Jeff J, Jhun M.A, Katz R, Kifley A, Kilpelainen T.O, Kumar A, Laakso M, Li-Gao R, Lohman K, Lu Y, Magi R, Malerba G, Mihailov E, Mohlke K.L, Mook-Kanamori D.O, Robino A, Ruderfer D, Salvi E, Schick U.M, Schulz C.A, Smith A.V, Smith J.A, Traglia M, Yerges-Armstrong L.M, Zhao W, Goodarzi M.O, Kraja A.T, Liu C, Wessel J, Charge Glycemic-T2D Working Group, Charge Blood Pressure Working Group, Boerwinkle E, Borecki I.B, Bork-Jensen J, Bottinger E.P, Braga D, Brandslund I, Brody J.A, Campbell A, Carey D.J, Christensen C, Coresh J, Crook E, Curhan G.C, Cusi D, de Boer I.H, de Vries A.P, Denny J.C, Devuyst O, Dreisbach A.W, Endlich K, Esko T, Franco O.H, Fulop T, Gerhard G.S, Glumer C, Gottesman O, Grarup N, Gudnason V, Harris T.B, Hayward C, Hocking L, Hofman A, Hu F.B, Husemoen L.L, Jackson R.D, Jorgensen T, Jorgensen M.E, Kahonen M, Kardia S.L, Konig W, Kooperberg C, Kriebel J, Launer L.J, Lauritzen T, Lehtimaki T, Levy D, Linksted P, Linneberg A, Liu Y, Loos R.J, Lupo A, Meisinger C, Melander O, Metspalu A, Mitchell P, Nauck M, Nurnberg P, Orho-Melander M, Parsa A, Pedersen O, Peters A, Peters U, Polasek O, Porteous D, Probst-Hensch N.M, Psaty B.M, Qi L, Raitakari O.T, Reiner A.P, Rettig R, Ridker P.M, Rivadeneira F, Rossouw J.E, Schmidt F, Siscovick D, Soranzo N, Strauch K, Toniolo D, Turner S.T, Uitterlinden A.G, Ulivi S, Velayutham D, Volker U, Volzke H, Waldenberger M, Wang J.J, Weir D.R, Witte D, Kuivaniemi H, Fox C.S, Franceschini N, Goessling W, Kottgen A, Chu A.Y. SOS2 and ACP1 loci identified through large-scale exome chip analysis regulate kidney development and function. J Am Soc Nephrol. 2017;28(3):981-994. DOI: 10.1681/ASN.2016020131
Machin M, Amaral A.F, Wielscher M, Rezwan F.I, Imboden M, Jarvelin M.R, Adcock I.M, Probst-Hensch N, Holloway J.W, Jarvis D.L. Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies. BMC Pulm Med. 2017;17:54. DOI: 10.1186/s12890-017-0397-3
Rava M, Ahmed I, Kogevinas M, Le Moual N, Bouzigon E, Curjuric I, Dizier M.H, Dumas O, Gonzalez J.R, Imboden M, Mehta A.J, Tubert-Bitter P, Zock J.P, Jarvis D, Probst-Hensch N.M, Demenais F, Nadif R. Genes interacting with occupational exposures to low molecular weight agents and irritants on adult-onset asthma in three European studies. Environ Health Perspect. 2017;125(2):207-214. DOI: 10.1289/EHP376