Publications

Schreidah C, Giesbrecht D, Gashema P, Young N.W, Munyaneza T, Muvunyi C.M, Thwai K, Mazarati J.B, Bailey J.A, Juliano J.J, Karema C. Expansion of artemisinin partial resistance mutations and lack of histidine rich protein-2 and -3 deletions in Plasmodium falciparum infections from Rukara, Rwanda. Malar J. 2024;23:150. DOI: 10.1186/s12936-024-04981-4

Kirby R, Giesbrecht D, Karema C, Watson O, Lewis S, Munyaneza T, Butera J.D, Juliano J.J, Bailey J.A, Mazarati J.B. Examining the early distribution of the artemisinin-resistant Plasmodium falciparum kelch13 R561H mutation in areas of higher transmission in Rwanda. Open Forum Infect Dis. 2023;10(4):ofad149. DOI: 10.1093/ofid/ofad149

Monroe A, Williams N.A, Ogoma S, Karema C, Okumu F. Reflections on the 2021 World Malaria Report and the future of malaria control. Malar J. 2022;21:154. DOI: 10.1186/s12936-022-04178-7

WorldWide Antimalarial Resistance Network - Falciparum Haematology Study Group. Haematological consequences of acute uncomplicated falciparum malaria: a WorldWide Antimalarial Resistance Network pooled analysis of individual patient data. BMC Med. 2022;20:85. DOI: 10.1186/s12916-022-02265-9

WorldWide Antimalarial Resistance Network - Methodology Study Group. Temporal distribution of Plasmodium falciparum recrudescence following artemisinin-based combination therapy: an individual participant data meta-analysis. Malar J. 2022;21:106. DOI: 10.1186/s12936-021-03980-z

Ndwiga L, Kimenyi K.M, Wamae K, Osoti V, Akinyi M, Omedo I, Ishengoma D.S, Duah-Quashie N, Andagalu B, Ghansah A, Amambua-Ngwa A, Tukwasibwe S, Tessema S.K, Karema C, Djimde A.A, Dondorp A.M, Raman J, Snow R.W, Bejon P, Ochola-Oyier L.I. A review of the frequencies of Plasmodium falciparum Kelch 13 artemisinin resistance mutations in Africa. Int J Parasitol Drugs Drug Resist. 2021;16:155-161. DOI: 10.1016/j.ijpddr.2021.06.001

Bretscher M.T, Dahal P, Griffin J, Stepniewska K, Bassat Q, Baudin E, D'Alessandro U, Djimde A.A, Dorsey G, Espie E, Fofana B, Gonzalez R, Juma E, Karema C, Lasry E, Lell B, Lima N, Menendez C, Mombo-Ngoma G, Moreira C, Nikiema F, Ouedraogo J.B, Staedke S.G, Tinto H, Valea I, Yeka A, Ghani A.C, Guerin P.J, Okell L.C. The duration of chemoprophylaxis against malaria after treatment with artesunate-amodiaquine and artemether-lumefantrine and the effects of pfmdr1 86Y and pfcrt 76T: a meta-analysis of individual patient data. BMC Med. 2020;18:47. DOI: 10.1186/s12916-020-1494-3

Karema C, Wen S, Sidibe A, Smith J.L, Gosling R, Hakizimana E, Tanner M, Noor A.M, Tatarsky A. History of malaria control in Rwanda: implications for future elimination in Rwanda and other malaria-endemic countries. Malar J. 2020;19:356. DOI: 10.1186/s12936-020-03407-1

GBD 2016 Healthcare Access and Quality Collaborators. Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016. Lancet. 2018;391(10136):2236-2271. DOI: 10.1016/S0140-6736(18)30994-2

GBD 2017 Causes of Death Collaborators. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392(10159):1736-1788. DOI: 10.1016/S0140-6736(18)32203-7

GBD 2017 DALYs and HALE Collaborators. Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392(10159):1859-1922. DOI: 10.1016/S0140-6736(18)32335-3

GBD 2017 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392(10159):1789-1858. DOI: 10.1016/S0140-6736(18)32279-7

GBD 2017 Mortality Collaborators. Global, regional, and national age-sex-specific mortality and life expectancy, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392(10159):1684-1735. DOI: 10.1016/S0140-6736(18)31891-9

GBD 2017 Population and Fertility Collaborators. Population and fertility by age and sex for 195 countries and territories, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392(10159):1995-2051. DOI: 10.1016/S0140-6736(18)32278-5

GBD 2017 Risk Factor Collaborators. Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Stu. Lancet. 2018;392(10159):1923-1994. DOI: 10.1016/S0140-6736(18)32225-6

Hakizimana E, Karema C, Munyakanage D, Githhure J, Baptise J, Mazarati J.E, Tongren J.E, Takken W, Binagwaho A, Koenraadt C.J.M. Spatio-temporal distribution of mosquitoes and risk of malaria infection in Rwanda. Acta Trop. 2018;182:149-157. DOI: 10.1016/j.actatropica.2018.02.012

Eckert E, Florey L.S, Tongren J.E, Salgado S.R, Rukundo A, Habimana J.P, Hakizimana E, Munguti K, Umulisa N, Mulindahabi M, Karema C. Impact evaluation of malaria control interventions on morbidity and all-cause child mortality in Rwanda, 2000-2010. Am J Trop Med Hyg. 2017;97:99-110. DOI: 10.4269/ajtmh.17-0281

GBD 2016 DALYs Hale Collaborators. Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017;390(10100):1260-1344. DOI: 10.1016/S0140-6736(17)32130-X

GBD 2016 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017;390(10100):1211-1259. DOI: 10.1016/S0140-6736(17)32154-2

GBD 2016 Mortality Collaborators. Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017;390(10100):1084-1150. DOI: 10.1016/S0140-6736(17)31833-0

GBD 2016 Risk Factors Collaborators. Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017;390(10100):1345-1422. DOI: 10.1016/S0140-6736(17)32366-8

GBD 2016 SDG Collaborators. Measuring progress and projecting attainment on the basis of past trends of the health-related Sustainable Development Goals in 188 countries: an analysis from the Global Burden of Disease Study 2016. Lancet. 2017;390(10100):1423-1459. DOI: 10.1016/S0140-6736(17)32336-X

Kozycki C.T, Umulisa N, Rulisa S, Mwikarago E.I, Musabyimana J.P, Habimana J.P, Karema C, Krogstad D.J. False-negative malaria rapid diagnostic tests in Rwanda: impact of Plasmodium falciparum isolates lacking hrp2 and declining malaria transmission. Malar J. 2017;16:123. DOI: 10.1186/s12936-017-1768-1

Nyandwi E, Veldkamp A, Amer S, Karema C, Umulisa I. Schistosomiasis mansoni incidence data in Rwanda can improve prevalence assessments, by providing high-resolution hotspot and risk factors identification. BMC Public Health. 2017;17:845. DOI: 10.1186/s12889-017-4816-4

Theiss-Nyland K, Koné D, Karema C, Ejersa W, Webster J, Lines J. The relative roles of ANC and EPI in the continuous distribution of LLINs: a qualitative study in four countries. Health Policy Plan. 2017;32(4):467-475. DOI: 10.1093/heapol/czw158

Zwang J, D'Alessandro U, Ndiaye J.L, Djimdé A.A, Dorsey G, Martensson A.A, Karema C, Olliaro P.L. Haemoglobin changes and risk of anaemia following treatment for uncomplicated falciparum malaria in sub-Saharan Africa. BMC Infect Dis. 2017;17:443. DOI: 10.1186/s12879-017-2530-6

Binagwaho A, Fawzi M.C, Agbonyitor M, Nsanzimana S, Karema C, Remera E, Mutabazi V, Shyirambere C, Cyamatare P, Nutt C, Wagner C, Condo J, Misago N, Kayiteshonga Y. Validating the children's depression inventory in the context of Rwanda. BMC Pediatr. 2016;16:29. DOI: 10.1186/s12887-016-0565-2

Gatera M, Bhatt S, Ngabo F, Utamuliza M, Sibomana H, Karema C, Mugeni C, Nutt C.T, Nsanzimana S, Wagner C.M, Binagwaho A. Successive introduction of four new vaccines in Rwanda: high coverage and rapid scale up of Rwanda's expanded immunization program from 2009 to 2013. Vaccine. 2016;34(29):3420-3426. DOI: 10.1016/j.vaccine.2015.11.076

GBD 2015 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016;388(10053):1545-1602. DOI: 10.1016/S0140-6736(16)31678-6

GBD 2015 Mortality and Causes of Death Collaborators. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016;388(10053):1459-1544. DOI: 10.1016/S0140-6736(16)31012-1

GBD 2015 SDG Collaborators. Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015. Lancet. 2016;388(10053):1813-1850. DOI: 10.1016/S0140-6736(16)31467-2

Hakizimana E, Karema C, Munyakanage D, Iranzi G, Githure J, Tongren J.E, Takken W, Binagwaho A, Koenraadt C.J. Susceptibility of Anopheles gambiae to insecticides used for malaria vector control in Rwanda. Malar J. 2016;15:582. DOI: 10.1186/s12936-016-1618-6

Ménard D, Khim N, Beghain J, Adegnika A.A, Shafiul-Alam M, Amodu O, Rahim-Awab G, Barnadas C, Berry A, Boum Y, Bustos M.D, Cao J, Chen J.H, Collet L, Cui L, Thakur G.D, Dieye A, Djalle D, Dorkenoo M.A, Eboumbou-Moukoko C.E, Espino F.E, Fandeur T, Ferreira-da-Cruz M.F, Fola A.A, Fuehrer H.P, Hassan A.M, Herrera S, Hongvanthong B, Houze S, Ibrahim M.L, Jahirul-Karim M, Jiang L, Kano S, Ali-Khan W, Khanthavong M, Kremsner P.G, Lacerda M, Leang R, Leelawong M, Li M, Lin K, Mazarati J.B, Menard S, Morlais I, Muhindo-Mavoko H, Musset L, Na-Bangchang K, Nambozi M, Niare K, Noedl H, Ouedraogo J.B, Pillai D.R, Pradines B, Quang-Phuc B, Ramharter M, Randrianarivelojosia M, Sattabongkot J, Sheikh-Omar A, Silue K.D, Sirima S.B, Sutherland C, Syafruddin D, Tahar R, Tang L.H, Toure O.A, Tshibangu-wa-Tshibangu P, Vigan-Womas I, Warsame M, Wini L, Zakeri S, Kim S, Eam R, Berne L, Khean C, Chy S, Ken M, Loch K, Canier L, Duru V, Legrand E, Barale J.C, Stokes B, Straimer J, Witkowski B, Fidock D.A, Rogier C, Ringwald P, Ariey F, Mercereau-Puijalon O, Karma Consortium. A worldwide map of Plasmodium falciparum K13-propeller polymorphisms. N Engl J Med. 2016;374(25):2453-2464. DOI: 10.1056/NEJMoa1513137

Sifft K.C, Geus D, Mukampunga C, Mugisha J.C, Habarugira F, Fraundorfer K, Bayingana C, Ndoli J, Umulisa I, Karema C, von Samson-Himmelstjerna G, Aebischer T, Martus P, Sendegeya A, Gahutu J.B, Mockenhaupt F.P. Asymptomatic only at first sight: malaria infection among schoolchildren in highland Rwanda. Malar J. 2016;15:553. DOI: 10.1186/s12936-016-1606-x

Theiss-Nyland K, Ejersa W, Karema C, Koné D, Koenker H, Cyaka Y, Lynch M, Webster J, Lines J. Operational challenges to continuous LLIN distribution: a qualitative rapid assessment in four countries. Malar J. 2016;15:131. DOI: 10.1186/s12936-016-1184-y

Thomson D.R, Semakula M, Hirschhorn L.R, Murray M, Ndahindwa V, Manzi A, Mukabutera A, Karema C, Condo J, Hedt-Gauthier B. Applied statistical training to strengthen analysis and health research capacity in Rwanda. Health Res Policy Syst. 2016;14(1):73. DOI: 10.1186/s12961-016-0144-x

WWARN Gametocyte Study Group. Gametocyte carriage in uncomplicated Plasmodium falciparum malaria following treatment with artemisinin combination therapy: a systematic review and meta-analysis of individual patient data. BMC Med. 2016;14:79. DOI: 10.1186/s12916-016-0621-7

Murray C.J, Ortblad K.F, Guinovart C, Lim S.S, Wolock T.M, Roberts D.A, Dansereau E.A, Graetz N, Barber R.M, Brown J.C, Wang H, Duber H.C, Naghavi M, Dicker D, Dandona L, Salomon J.A, Heuton K.R, Foreman K, Phillips D.E, Fleming T.D, Flaxman A.D, Phillips B.K, Johnson E.K, Coggeshall M.S, Abd-Allah F, Abera S.F, Abraham J.P, Abubakar I, Abu-Raddad L.J, Abu-Rmeileh N.M, Achoki T, Adeyemo A.O, Adou A.K, Adsuar J.C, Agardh E.E, Akena D, Al Kahbouri M.J, Alasfoor D, Albittar M.I, Alcala-Cerra G, Alegretti M.A, Alemu Z.A, Alfonso-Cristancho R, Alhabib S, Ali R, Alla F, Allen P.J, Alsharif U, Alvarez E, Alvis-Guzman N, Amankwaa A.A, Amare A.T, Amini H, Ammar W, Anderson B.O, Antonio C.A, Anwari P, Arnlov J, Arsenijevic V.S, Artaman A, Asghar R.J, Assadi R, Atkins L.S, Badawi A, Balakrishnan K, Banerjee A, Basu S, Beardsley J, Bekele T, Bell M.L, Bernabe E, Beyene T.J, Bhala N, Bhalla A, Bhutta Z.A, Abdulhak A.B, Binagwaho A, Blore J.D, Bose D, Brainin M, Breitborde N, Castaneda-Orjuela C.A, Catala-Lopez F, Chadha V.K, Chang J.C, Chiang P.P, Chuang T.W, Colomar M, Cooper L.T, Cooper C, Courville K.J, Cowie B.C, Criqui M.H, Dandona R, Dayama A, De Leo D, Degenhardt L, Del Pozo-Cruz B, Deribe K, Des Jarlais D.C, Dessalegn M, Dharmaratne S.D, Dilmen U, Ding E.L, Driscoll T.R, Durrani A.M, Ellenbogen R.G, Ermakov S.P, Esteghamati A, Faraon E.J, Farzadfar F, Fereshtehnejad S.M, Fijabi D.O, Forouzanfar M.H, Fra Paleo U, Gaffikin L, Gamkrelidze A, Gankpe F.G, Geleijnse J.M, Gessner B.D, Gibney K.B, Ginawi I.A, Glaser E.L, Gona P, Goto A, Gouda H.N, Gugnani H.C, Gupta R, Gupta R, Hafezi-Nejad N, Hamadeh R.R, Hammami M, Hankey G.J, Harb H.L, Haro J.M, Havmoeller R, Hay S.I, Hedayati M.T, Pi I.B, Hoek H.W, Hornberger J.C, Hosgood H.D, Hotez P.J, Hoy D.G, Huang J.J, Iburg K.M, Idrisov B.T, Innos K, Jacobsen K.H, Jeemon P, Jensen P.N, Jha V, Jiang G, Jonas J.B, Juel K, Kan H, Kankindi I, Karam N.E, Karch A, Karema C.K, Kaul A, Kawakami N, Kazi D.S, Kemp A.H, Kengne A.P, Keren A, Kereselidze M, Khader Y.S, Khalifa S.E, Khan E.A, Khang Y.H, Khonelidze I, Kinfu Y, Kinge J.M, Knibbs L, Kokubo Y, Kosen S, Defo B.K, Kulkarni V.S, Kulkarni C, Kumar K, Kumar R.B, Kumar G.A, Kwan G.F, Lai T, Balaji A.L, Lam H, Lan Q, Lansingh V.C, Larson H.J, Larsson A, Lee J.T, Leigh J, Leinsalu M, Leung R, Li Y, Li Y, de Lima G.M, Lin H.H, Lipshultz S.E, Liu S, Liu Y, Lloyd B.K, Lotufo P.A, Machado V.M, Maclachlan J.H, Magis-Rodriguez C, Majdan M, Mapoma C.C, Marcenes W, Marzan M.B, Masci J.R, Mashal M.T, Mason-Jones A.J, Mayosi B.M, Mazorodze T.T, Mckay A.C, Meaney P.A, Mehndiratta M.M, Mejia-Rodriguez F, Melaku Y.A, Memish Z.A, Mendoza W, Miller T.R, Mills E.J, Mohammad K.A, Mokdad A.H, Mola G.L, Monasta L, Montico M, Moore A.R, Mori R, Moturi W.N, Mukaigawara M, Murthy K.S, Naheed A, Naidoo K.S, Naldi L, Nangia V, Narayan K.M, Nash D, Nejjari C, Nelson R.G, Neupane S.P, Newton C.R, Ng M, Nisar M.I, Nolte S, Norheim O.F, Nowaseb V, Nyakarahuka L, Oh I.H, Ohkubo T, Olusanya B.O, Omer S.B. Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2014;384(9947):1005-1070. DOI: 10.1016/S0140-6736(14)60844-8