Automated high throughput analysis of antiretroviral drugs in dried blood spots (Publications)
For therapeutic drug monitoring (TDM) in remote settings, dried blood spots (DBS) are particularly advantageous, as blood sample collection and handling is uncomplicated. The aim of this study was to
Accuracy of diagnostic tests for <em>Schistosoma mansoni</em> infection in asymptomatic Eritrean refugees: serology and POC-CCA against stool... (Publications)
Background: The unprecedented increase in number of African refugees arriving in Europe is confronting clinicians and general practitioners with the question of whether or not and how to screen migran
Estimation of malaria parasite reservoir coverage using reactive case detection and active community fever screening from census data with rapid... (Publications)
BACKGROUND AND METHODS: In areas where malaria transmission has been suppressed by vector control interventions many malaria control and elimination programmes are actively seeking new interventions t
Clinical and laboratory predictors of death in African children with features of severe malaria: a systematic review and meta-analysis (Publications)
BACKGROUND: The criteria for defining severe malaria have evolved over the last 20 years. We aimed to assess the strength of association of death with features currently characterizing severe malaria
The antitrypanosomal and antitubercular activity of some nitro(triazole/imidazole)-based aromatic amines (Publications)
A limited number of novel 3-nitrotriazole- and 2-nitroimidazole-linked quinolines and quinazolines were synthesized and screened for in vitro antitrypanosomal and antitubercular activities as well as
Antimalarial inhibitors targeting serine hydroxymethyltransferase (SHMT) with <em>in vivo</em> efficacy and analysis of their binding mode based on... (Publications)
Target-based approaches toward new antimalarial treatments are highly valuable to prevent resistance development. We report several series of pyrazolopyran-based inhibitors targeting the enzyme serine
3-hydroxy-N'-arylidenepropanehydrazonamides with halo-substituted phenanthrene scaffolds cure <em>P. berghei</em> infected mice when administered... (Publications)
Structural optimization of 3-hydroxy-N'-arylidenepropanehydrazonamides provided new analogs with nanomolar to subnanomolar antiplasmodial activity against asexual blood stages of Plasmodium falciparum
Tracking development assistance and government health expenditures for 35 malaria-eliminating countries: 1990-2017 (Publications)
BACKGROUND: Donor financing for malaria has declined since 2010 and this trend is projected to continue for the foreseeable future. These reductions have a significant impact on lower burden countries