<em>In vitro</em> and<em> in vivo</em> activity of R- and S-praziquantel enantiomers and the main human metabolite trans-4-hydroxy-praziquantel... (Publications)
BACKGROUND: Praziquantel (PZQ) is the mainstay of schistosomiasis control and has been successfully used for decades. However, its mechanism of action is not fully understood. While the majority of st
Bifurcatriol, a new antiprotozoal acyclic diterpene from the brown alga <em>Bifurcaria bifurcata</em> (Publications)
Linear diterpenes that are commonly found in brown algae are of high chemotaxonomic and ecological importance. This study reports bifurcatriol (1), a new linear diterpene featuring two stereogenic cen
Childhood hospitalisation and related deaths in Hanoi, Vietnam: a tertiary hospital database analysis from 2007 to 2014 (Publications)
OBJECTIVE: To describe hospital admission and emergency visit rates and potential risk factors of prolonged hospitalisation and death among children in Hanoi. STUDY DESIGN: A retrospective study revie
Mixed Th1 and Th2 <em>Mycobacterium tuberculosis</em>-specific CD4 T cell responses in patients with active pulmonary tuberculosis from Tanzania (Publications)
Mycobacterium tuberculosis (Mtb) and helminth infections elicit antagonistic immune effector functions and are co-endemic in several regions of the world. We therefore hypothesized that helminth infec
Live and stillborn very low birthweight infants in Switzerland: comparison between hospital based birth registers and the national birth register (Publications)
Background and aim: Perinatal and infant mortality rates are considered key indicators of medical care. The aim of this investigation was to examine how representative and reliable the official nation
Preservation of sputum samples with cetylpyridinium chloride (CPC) for tuberculosis cultures and Xpert MTB/RIF in a low-income country (Publications)
BACKGROUND: Culture contamination with environmental bacteria is a major challenge in tuberculosis (TB) laboratories in hot and humid climate zones. We studied the effect of cetylpyridinium chloride (