Kyasanur forest disease: state-of-the-art review (Publications)
Kyasanur Forest Disease (KFD) virus is a flavivirus that can be transmitted to humans from monkeys or other mammals through hard ticks (Haemaphysalis spinigera). The disease is endemic to sixteen dist
<em>P. falciparum</em> and <em>P. vivax</em> orthologous coiled-coil candidates for a potential cross-protective vaccine (Publications)
Over the last four decades, significant efforts have been invested to develop vaccines against malaria. Although most efforts are focused on the development of P. falciparum vaccines, the current avai
HIV-associated neurocognitive impairment in stable people living with HIV on ART in rural Tanzania (Publications)
OBJECTIVES: Few studies have assessed cognitive impairment among healthy people living with HIV (PLWH) who are stable on antiretroviral treatment (ART) in sub-Saharan Africa. METHODS: We conducted a c
District health management and its association with health system performance in the Eastern Region of Ghana (Publications)
Introduction: Effective and efficient management and leadership play an important role in ensuring robust and responsive health systems worldwide. In many African countries, including Ghana, which is
Development of novel strategies to fill the empty drug pipeline for schistosomiasis: from drug sensitivity assay development to preclinical studies (Publications)
Schistosomiasis is a neglected tropical disease caused by Schistosoma spp. parasites. It affects more than 200 million people and 700 million more are at risk. Over 10’000 people die every year becaus
New methodological approaches to monitor long lasting insecticidal nets (LLINs) durability for sustained malaria control (Publications)
Long lasting insecticidal nets (LLINs) are the current primary vector control measure to prevent malaria transmission. They function by inhibiting mosquitoes from blood feeding and also killing mosqui
A high-throughput cell- and virus-free assay shows reduced neutralization of SARS-CoV-2 variants by COVID-19 convalescent plasma (Publications)
The detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific antibodies in the serum of an individual indicates prior infection or vaccination. However, it provides limited i
Common haplotypes at the <em>CFH </em>locus and low-frequency variants in <em>CFHR2 </em>and <em>CFHR5 </em>associate with systemic FHR concentrations... (Publications)
Age-related macular degeneration (AMD) is the principal cause of blindness in the elderly population. A strong effect on AMD risk has been reported for genetic variants at the CFH locus, encompassing
Two-target quantitative PCR to predict library composition for shallow shotgun sequencing (Publications)
When determining human microbiota composition, shotgun sequencing is a powerful tool that can generate high-resolution taxonomic and functional information at once. However, the technique is limited b