<em>In silico</em> prediction and experimental evaluation of furanoheliangolide sesquiterpene lactones as potent agents against <em>Trypanosoma brucei... (Publications)
In continuation of our earlier study on the in vitro antiprotozoal activity of 40 natural sesquiterpene lactones (STLs), we extended the set of tested compounds from our laboratories to 59. On the bas
Improved services to enrollees into an HIV rural care and treatment center in Tanzania [Short communication] (Publications)
Better quality of services is essential for the sustainability of HIV programs, in particular in rural Sub-Saharan Africa, to support the increasing number of individuals treated with combination anti
In vitro and in vivo characterization of the antimalarial lead compound SSJ-183 in <em>Plasmodium</em> models (Publications)
The objective of this work was to characterize the in vitro (Plasmodium falciparum) and in vivo (Plasmodium berghei) activity profile of the recently discovered lead compound SSJ-183. The molecule sho
Development of a glycoconjugate vaccine to prevent meningitis in Africa caused by meningococcal serogroup X (Publications)
Neisseria meningitidis is a major cause of bacterial meningitis worldwide, especially in the African meningitis belt, and has a high associated mortality. The meningococcal serogroups A, W, and X have
DMSO-mediated ligand dissociation: renaissance for biological activity of <em>N</em>-heterocyclic-[Ru(n6-arene)CI2] drug candidates (Publications)
Slipped under the radar? 1 H NMR spectroscopic examination revealed that [Ru(?6 -arene)Cl2 (L)] (L=N-heterocyclic ligands) complexes readily undergo ligand exchange reaction in DMSO, a popular medium
Pulsed radio-frequency electromagnetic fields: dose-dependent effects on sleep, the sleep EEG and cognitive performance (Publications)
To establish a dose-response relationship between the strength of electromagnetic fields (EMF) and previously reported effects on the brain, we investigated the influence of EMF exposure by varying th
Mental health litaracy and the experience of depression in a community sample of gay men (Publications)
BACKGROUND: Gay men are at higher risk of suffering from a variety of psychiatric disorders, yet the mental health literacy of this population has remained largely unknown. METHODS: In 2007 and 2011,