Health impacts of anthropogenic biomass burning in the developed world (Publications)
Climate change policies have stimulated a shift towards renewable energy sources such as biomass. The economic crisis of 2008 has also increased the practice of household biomass burning as it is ofte
Discovery of inhibitors of<em> Trypanosoma brucei</em> by phenotypic screening of a focused protein kinase library (Publications)
A screen of a focused kinase inhibitor library against Trypanosoma brucei rhodesiense led to the identification of seven series, totaling 121 compounds, which showed > 50 % inhibition at 5 muM. Screen
How do clinicians prefer cultural competence training? Findings from the DSM-5 cultural formulation interview field trial (Publications)
OBJECTIVE: This study's objective is to analyze training methods clinicians reported as most and least helpful during the DSM-5 Cultural Formulation Interview field trial, reasons why, and association
Matching comprehensive health insurance reimbursements to their real costs: the case of antenatal care visits in a region of Peru (Publications)
BACKGROUND: Prepaid contributory systems are increasingly being recognized as key mechanisms in achieving universal health coverage in low and middle-income countries. Peru created the Seguro Integral
Preparation of antimalarial endoperoxides by a formal [2 + 2 + 2] cycloaddition (Publications)
A formal [2 + 2 + 2] cycloaddition reaction between a 1,3-dione, an olefin, and molecular oxygen mediated by light is reported, which delivers endoperoxides in good yield through the formation of two
Highly antiplasmodial non-natural oxidative products of dioncophylline A: synthesis, absolute configuration, and conformational stability (Publications)
Four new compounds, the monomeric dioncotetralones A (6 a) and B (6 b) and the dimeric compounds jozimine A3 (7) and jozimine A4 (9), were semi-synthesized from the natural product dioncophylline A (4
Is <em>Caenorhabditis elegans</em> the magic bullet for anthelminthic drug discovery? (Publications)
Recent advances in handling and readout have facilitated high-throughput screens with Caenorhabditis elegans. A new study demonstrates that C. elegans is a useful tool in high-throughput anthelminthic
A novel isothermal microcalorimetry tool to assess drug effects on<em> Ancylostoma ceylanicum</em> and <em>Necator americanus</em> (Publications)
Soil-transmitted helminths, which affect the poorest communities, worldwide cause a range of symptoms and morbidity, yet few treatment options are available and drug resistance is a concern. To improv