Genetic diversity of expressed <em>Plasmodium falciparum</em> var genes from Tanzanian children with severe malaria (Publications)
BACKGROUND: Severe malaria has been attributed to the expression of a restricted subset of the var multigene family, which encodes for Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1). Pf
Cost implications of improving malaria diagnosis: findings from north-eastern Tanzania (Publications)
BACKGROUND: Over diagnosis of malaria contributes to improper treatment, wastage of drugs and resistance to the few available drugs. This paper attempts to estimate the rates of over diagnosis of mala
Malaria transmission after five years of vector control on Bioko Island, Equatorial Guinea (Publications)
ABSTRACT: BACKGROUND: Malaria is endemic with year-round transmission on Bioko Island. The Bioko Island Malaria Control Project (BIMCP) started in 2004 with the aim to reduce malaria transmission and
Molecular surveillance of drug resistance through imported isolates of <em>Plasmodium falciparum</em> in Europe (Publications)
BACKGROUND: Results from numerous studies point convincingly to correlations between mutations at selected genes and phenotypic resistance to antimalarials in Plasmodium falciparum isolates. In order
Genetic reconstruction of protozoan rRNA decoding sites provides a rationale for paromomycin activity against <em>Leishmania</em> and... (Publications)
Aminoglycoside antibiotics target the ribosomal decoding A-site and are active against a broad spectrum of bacteria. These compounds bind to a highly conserved stem-loop-stem structure in helix 44 of
Tick-borne diseases in Switzerland and climate change (Publications)
Tick-borne diseases are the most common vector-borne diseases in Europe. In Central Europe, the tick Ixodes ricinus is responsible for most tick bites. Next to tick borne encephalitis (TBE or in Germa