A community-randomised evaluation of the effect of IPTi on anti-malarial drug resistance in southern Tanzania (Publications)
Background: Intermittent Preventive Treatment in infants (IPTi) is the administration of sulphadoxine-pyrimethamine (SP) at 2, 3 and 9 months of age to prevent malaria. We investigated the influence o
Cord blood allergen-specific IgE is associated with reduced IFN-gamma production by cord blood cells: The Protection against Allergy-Study in Rural... (Publications)
BACKGROUND: It is currently discussed whether allergic sensitization may start in utero under the influence of the maternal immune system and environmental determinants. OBJECTIVE: To investigate the
Malaria-infected mice are cured by oral administration of new artemisinin derivatives (Publications)
In four or five chemical steps from the 1,2,4-trioxane artemisinin, a new series of 23 trioxane dimers has been prepared. Eleven of these new trioxane dimers cure malaria-infected mice via oral dosing
Novel 3-nitro-1H-1,2,4-triazole-based aliphatic and aromatic amines as anti-chagasic agents (Publications)
A series of novel 2-nitro-1H-imidazole- and 3-nitro-1H-1,2,4-triazole-based aromatic and aliphatic amines were screened for anti-trypanosomal activity and mammalian cytotoxicity by the Drugs for Negle
Strongyloidiasis - the most neglected of the neglected tropical diseases? (Publications)
Soil-transmitted helminths of the genus Strongyloides (S. fuelleborni and the more prevalent S. stercoralis) are currently believed to infect an estimated 30-100 million people worldwide. The health c