Compensatory Evolution and Epistasis in Multidrug-Resistant Mycobacterium (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/compensatory-evolution-and-epistasis-in-multidrug-resistant-mycobacterium
Multidrug-resistant bacteria are a global threat to public health and the economy. Studies in model organisms suggest compensatory evolution and epistatic interactions between drug resistance-conferri
External Mandate for the Swiss Intermediate Body (Fund Manager) of the Thematic Fund (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/external-mandate-for-the-swiss-intermediate-body-fund-manager-of-the-thematic-fund
The public health system in Romania faces major challenges, despite considerable progress in recent years. Switzerland’s contribution to the enlarged EU therefore supports ongoing health reforms in a
Early life adversity, biological adaptation, and human capital: evidence from an interrupted malaria control program in Zambia (Publications)
Growing evidence from evolutionary biology demonstrates how early life shocks trigger physiological changes designed to be adaptive in challenging environments. We examine the implications of one type
Risk profiling and efficacy of albendazole against the hookworms<em> Necator americanus </em>and <em>Ancylostoma ceylanicum</em> in Cambodia to... (Publications)
Background: Hookworm disease is endemic throughout many parts of the Asia Pacific, despite targeted control programs of at-risk populations. The success of these programs has been hindered by the limi
Nonrandom selection and multiple blood feeding of human hosts by <em>Anopheles </em>vectors: implications for malaria transmission in Papua New Guinea (Publications)
Nonrandom selection and multiple blood feeding of human hosts by Anopheles mosquitoes may exacerbate malaria transmission. Both patterns of blood feeding and their relationship to malaria epidemiology
Hygroline derivatives from <em>Schizanthus tricolor </em>and their anti-trypanosomatid and antiplasmodial activities (Publications)
Chemical investigation of the alkaloid extract of the aerial parts of Schizanthus tricolor led to the targeted isolation of 26 hygroline derivatives of which 20 were fully characterized. They have not
Preventing leprosy with retrospective active case finding combined with single-dose rifampicin for contacts in a low endemic setting: results of the... (Publications)
Post-exposure prophylaxis (PEP) with single-dose rifampicin (SDR) reduces the risk of developing leprosy among contacts of leprosy patients. Most evidence for the feasibility of the intervention is fr
A descriptive qualitative case study of the experiences, perceptions, and attitudes of pregnant women on Unguja island, Zanzibar, towards... (Publications)
Many countries exclude pregnant and lactating women from mass drug administration (MDA) programmes with praziquantel against schistosomiasis due to historic safety concerns over drug use during gestat
Cancer risk in adolescents and young adults living with HIV in South Africa: a nationwide cohort study (Publications)
BACKGROUND: Literature on cancer in adolescents and young adults (AYA; aged 15-24 years) living with HIV is scarce. We studied cancer incidence in AYA living with HIV in South Africa between 2004 and