Synthesis of antiprotozoal diamines by regioselective insertion of nitrogen into a bicyclic ring system (Publications)
The regioselective insertion of nitrogen in a bicyclic octanone skeleton is reported. The structure was established by a single crystal structure analysis. The antiprotozoal activities of lactames and
4-Aminobicyclo[2.2.2]octan-2-yl 4-aminobutanoates with antiprotozoal activity (Publications)
A new series of 4-aminobicyclo[2.2.2]octan-2-yl 4-aminobutanoates have been prepared. Their activities against the multiresistant K-1 strain of Plasmodium falciparum and Trypanosoma brucei rhodesiense
Residential distance to high voltage power lines and risk of neurodegenerative diseases: a Danish population-based case-control study (Publications)
The aim of this study was to investigate the possible association between residential distance to high-voltage power lines and neurodegenerative diseases, especially Alzheimer's disease. A Swiss study
1-Aryl-1,2,3,4-tetrahydroisoquinolines as potential antimalarials: synthesis, in vitro antiplasmodial activity and in silico pharmacokinetics... (Publications)
In the present study, twenty-one 1-aryl-6-hydroxy-1,2,3,4-tetrahydroisoquinoline (THIQ) analogues were synthesized by base-catalyzed Pictet-Spengler reaction, and tested in vitro against P. falciparum