<em>SERPINA1</em> gene variants in individuals from the general population with reduced {alpha}1-antitrypsin concentrations (Publications)
BACKGROUND: Individuals with severe deficiency in serum alpha1-antitrypsin (AAT) concentrations are at high risk for developing chronic obstructive pulmonary disease (COPD), whereas those carrying the
An automated, interactive analysis system for ultrasound sequences of the common carotid artery (Publications)
Structural parameters of the common carotid artery (CCA) have shown to correlate with the risk of cardiovascular disease, but their precise measurement is challenging. We developed an automatic detect
Long-term ambient air pollution and respiratory symptoms in adults (SAPALDIA study) (Publications)
The association between long-term exposure to ambient air pollution and respiratory symptoms was investigated in a cross-sectional study in random population samples of adults (aged 18 to 60 yr, n = 9
Clinical diagnosis of current asthma: predictive value of respiratory symptoms in the SAPALDIA study. Swiss Study on Air Pollution and Lung Diseases... (Publications)
Bronchial asthma is a very common disease which often remains underdiagnosed. The aim of this study was to determine the predictive value of the most common respiratory symptoms and to explore the bes
Exposure to motor vehicle traffic and allergic sensitization. The Swiss Study on Air Pollution and Lung Diseases in Adults (SAPALDIA) Team (Publications)
We examined the association between the presence of an allergic sensitization and seasonal allergic diseases or symptoms and the exposure to road traffic in Basel, Switzerland. Traffic counts at the d
The association of a variant in the cell cycle control gene CCND1 and obesity on the development of asthma in the Swiss SAPALDIA study (Publications)
Objective. The molecular mechanisms underlying the association between obesity (BMI > /= 30 kg/m(2)) and asthma are poorly understood. Since shifts in the fate of bronchial cells due to low-grade syst
Effects of filter choice in GT3X accelerometer assessments of free-living activity (Publications)
PURPOSE: Actigraph accelerometers are widely used devices to objectively assess physical activity. The GT3X version has two filter options to be selected prior to data assessment (normal and low frequ
Asthma and the menopause: a systematic review and meta-analysis (Publications)
OBJECTIVE: To review the available literature to determine whether the menopausal transition is associated with asthma incidence.METHODS: We performed a systematic review and meta-analysis of cohort a