Mortality along the continuum of HIV care in Rwanda: a model-based analysis (Publications)
BACKGROUND: HIV is the leading cause of death among adults in sub-Saharan Africa. However, mortality along the HIV care continuum is poorly described. We combine demographic, epidemiologic, and health
Excretory/secretory products from the gastrointestinal nematode <em>Trichuris muris</em> (Publications)
To better control gastrointestinal nematode infections in humans and animals, it is important to understand the strategies used by these parasites to modulate the host immune system. In this regard, m
Whole genome sequencing distinguishes between relapse and reinfection in recurrent leprosy cases (Publications)
BACKGROUND: Since leprosy is both treated and controlled by multidrug therapy (MDT) it is important to monitor recurrent cases for drug resistance and to distinguish between relapse and reinfection as
Effects of long-term exposure to air pollution on natural-cause mortality: an analysis of 22 European cohorts within the multicentre ESCAPE project (Publications)
BACKGROUND: Few studies on long-term exposure to air pollution and mortality have been reported from Europe. Within the multicentre European Study of Cohorts for Air Pollution Effects (ESCAPE), we aim
Environmental tobacco smoke exposure and diabetes in adult never-smokers (Publications)
BACKGROUND: Active smoking has been linked to type 2 diabetes mellitus (T2DM) but only few recent studies have shown environmental tobacco smoke (ETS) to be associated with DM in never-smokers. We ass
Hypertension, diabetes and lifestyle in the long-term - results from a Swiss population-based cohort (Publications)
Healthy lifestyles are integral in preventing and treating common cardiovascular and metabolic diseases. The aim of this study was to observe smoking habits, alcohol intake, physical activity and body
Haemoglobin changes and risk of anaemia following treatment for uncomplicated falciparum malaria in sub-Saharan Africa (Publications)
BACKGROUND: Anaemia is common in malaria. It is important to quantitate the risk of anaemia and to distinguish factors related to the natural history of disease from potential drug toxicity. METHODS:
The within-host population dynamics of <em>Mycobacterium tuberculosi</em>s vary with treatment efficacy (Publications)
BACKGROUND: Combination therapy is one of the most effective tools for limiting the emergence of drug resistance in pathogens. Despite the widespread adoption of combination therapy across diseases, d
Natural immune response to <em>Plasmodium vivax </em>alpha-helical coiled coil protein motifs and its association with the risk of <em>P. vivax</em>... (Publications)
Protein alpha-helical coiled coil structures are known to induce antibodies able to block critical functions in different pathogens. In a previous study, a total of 50 proteins of Plasmodium vivax ery