Structure and biosynthesis of xenoamicins from entomopathogenic <em>Xenorhabdus</em> (Publications)
During the search for novel natural products from entomopathogenic Xenorhabdus doucetiae DSM17909 and X. mauleonii DSM17908 novel peptides named xenoamicins were identified in addition to the already
Methodologicel difficulties in the conduct of neuroepidemiological studies in low- and middle-income countries (Publications)
Background: The majority of people with epilepsy (PWE) live in low- and middle-income countries (LMICs). However, they remain largely untreated and the bulk of resources are used to treat patients in
Mikrobielles Umfeld und allergische Erkrankungen im Kindesalter (Publications)
Asthma and allergies are among the most frequent chronic diseases in childhood. Their prevalence has increased during the second half of the twentieth century but seem to stabilize in recent years in
Antitrypanosomal structure-activity-relationship study of synthetic cynaropicrin derivatives (Publications)
Cynaropicrin is a guaianolide sesquiterpene lactone with a 5-7-5 tricyclic skeleton, four exo-olefins, and two hydroxyl groups. Recently, it was found that the compound is a potent in vitro and in viv
B-type natriuretic peptide in patients undergoing orthopaedic surgery: a prospective cohort study (Publications)
BACKGROUND AND OBJECTIVE: Postoperative cardiac complications pose a substantial risk to patients undergoing orthopaedic surgery. METHODS: B-type natriuretic peptide (BNP) was determined preoperativel
Predictive risk mapping of schistosomiasis in Brazil using Bayesian geostatistical models (Publications)
Schistosomiasis is one of the most common parasitic diseases in tropical and subtropical areas, including Brazil. A national control programme has been instigated in Brazil in the mid-1970s and proved
Priorities for research on meningococcal disease and the impact of serogroup A vaccination in the African meningitis belt (Publications)
For over 100 years, large epidemics of meningococcal meningitis have occurred every few years in areas of the African Sahel and sub-Sahel known as the African meningitis belt. Until recently, the main
Targeting <em>Plasmodium</em> PI(4)K to eliminate malaria (Publications)
Achieving the goal of malaria elimination will depend on targeting Plasmodium pathways essential across all life stages. Here we identify a lipid kinase, phosphatidylinositol-4-OH kinase (PI(4)K), as