Importance of routine viral load monitoring: higher levels of resistance at ART failure in Uganda and Lesotho compared with Switzerland (Publications)
Objectives: Emerging resistance to antiretroviral drugs may jeopardize the achievements of improved access to ART. We compared the prevalence of different resistance mutations in HIV-infected adults w
Can the use of digital algorithms improve quality care? An example from Afghanistan (Publications)
BACKGROUND: Quality of care is a difficult parameter to measure. With the introduction of digital algorithms based on the Integrated Management of Childhood Illness (IMCI), we are interested to unders
Spatial-temporal heterogeneity in malaria receptivity is best estimated by vector biting rates in areas nearing elimination (Publications)
BACKGROUND: Decisions on when vector control can be withdrawn after malaria is eliminated depend on the receptivity or potential of an area to support vector populations. To guide malaria control and
Diagnostic performance of conventional and ultrasensitive rapid diagnostic tests for malaria in febrile outpatients in Tanzania (Publications)
Background: A novel ultra-sensitive malaria RDT (us-RDT) has been developed for improved active P.falciparum case detection. The utility of this us-RDT in clinical diagnosis and fever management has n
Come, sweet death: targeting glycosomal protein import for antitrypanosomal drug development (Publications)
Glycosomes evolved as specialized system for glycolysis in trypanosomatids. These organelle rely on protein import to maintain function. A machinery of peroxin (PEX) proteins is responsible for recogn